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Search Results to Stavros Manolagas

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One or more keywords matched the following items that are connected to Manolagas, Stavros

Item TypeName
Academic Article Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids.
Academic Article Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.
Academic Article Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism.
Academic Article Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis.
Academic Article Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation.
Academic Article Induction of osteoblast differentiation by selective activation of kinase-mediated actions of the estrogen receptor.
Academic Article Nongenotropic, anti-apoptotic signaling of 1alpha,25(OH)2-vitamin D3 and analogs through the ligand binding domain of the vitamin D receptor in osteoblasts and osteocytes. Mediation by Src, phosphatidylinositol 3-, and JNK kinases.
Academic Article Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens.
Academic Article Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha.
Academic Article Glucocorticoids and tumor necrosis factor a increase oxidative stress and suppress Wnt protein signaling in osteoblasts.
Academic Article A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction.
Academic Article Transduction of cell survival signals by connexin-43 hemichannels.
Academic Article Perspective: nonreproductive sites of action of reproductive hormones.
Academic Article Kinase-mediated transcription, activators of nongenotropic estrogen-like signaling (ANGELS), and osteoporosis: a different perspective on the HRT dilemma.
Academic Article Intermittent PTH stimulates periosteal bone formation by actions on post-mitotic preosteoblasts.
Academic Article Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc signaling cascade: counter regulation by estrogens or androgens.
Concept Protein Kinase C
Concept Phosphotransferases
Concept Ribosomal Protein S6 Kinases, 90-kDa
Concept MAP Kinase Signaling System
Concept MAP Kinase Kinase 4
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept JNK Mitogen-Activated Protein Kinases
Concept Extracellular Signal-Regulated MAP Kinases
Concept Phosphatidylinositol 3-Kinases
Concept Thymidine Kinase
Concept Mitogen-Activated Protein Kinase Kinases
Concept src-Family Kinases
Concept Mitogen-Activated Protein Kinase 1
Concept Mitogen-Activated Protein Kinases
Concept Focal Adhesion Kinase 1
Concept Focal Adhesion Kinase 2
Concept Cyclic AMP-Dependent Protein Kinases
Academic Article Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs.
Academic Article DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age.
Grant OSTEOBLAST COMMITMENT AND DIFFERENTIATION BY ANGELS

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  • Phosphotransferases