Encephalomyelitis, Autoimmune, Experimental
"Encephalomyelitis, Autoimmune, Experimental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
Descriptor ID |
D004681
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MeSH Number(s) |
C10.114.703.300 C10.228.140.695.562.250 C10.228.518.562.250 C10.314.350.250 C20.111.258.625.300 E05.598.500.500.500
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Concept/Terms |
Encephalomyelitis, Autoimmune, Experimental- Encephalomyelitis, Autoimmune, Experimental
- Allergic Encephalomyelitis, Experimental
- Encephalomyelitis, Experimental Allergic
- Experimental Allergic Encephalomyelitides
- Autoimmune Encephalomyelitis, Experimental
- Experimental Autoimmune Encephalomyelitis
- Encephalomyelitis, Allergic
- Encephalomyelitis, Experimental Autoimmune
- Experimental Allergic Encephalomyelitis
- Allergic Encephalomyelitis
- Autoimmune Experimental Encephalomyelitis
- Encephalomyelitis, Autoimmune Experimental
- Experimental Encephalomyelitis, Autoimmune
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Below are MeSH descriptors whose meaning is more general than "Encephalomyelitis, Autoimmune, Experimental".
- Diseases [C]
- Nervous System Diseases [C10]
- Autoimmune Diseases of the Nervous System [C10.114]
- Nervous System Autoimmune Disease, Experimental [C10.114.703]
- Encephalomyelitis, Autoimmune, Experimental [C10.114.703.300]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Leukoencephalopathies [C10.228.140.695]
- Demyelinating Autoimmune Diseases, CNS [C10.228.140.695.562]
- Encephalomyelitis, Autoimmune, Experimental [C10.228.140.695.562.250]
- Leukoencephalopathies [C10.228.518]
- Demyelinating Autoimmune Diseases, CNS [C10.228.518.562]
- Encephalomyelitis, Autoimmune, Experimental [C10.228.518.562.250]
- Demyelinating Diseases [C10.314]
- Demyelinating Autoimmune Diseases, CNS [C10.314.350]
- Encephalomyelitis, Autoimmune, Experimental [C10.314.350.250]
- Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]
- Autoimmune Diseases of the Nervous System [C20.111.258]
- Nervous System Autoimmune Disease, Experimental [C20.111.258.625]
- Encephalomyelitis, Autoimmune, Experimental [C20.111.258.625.300]
- Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
- Investigative Techniques [E05]
- Models, Animal [E05.598]
- Disease Models, Animal [E05.598.500]
- Nervous System Autoimmune Disease, Experimental [E05.598.500.500]
- Encephalomyelitis, Autoimmune, Experimental [E05.598.500.500.500]
Below are MeSH descriptors whose meaning is more specific than "Encephalomyelitis, Autoimmune, Experimental".
This graph shows the total number of publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in UAMS Profiles by year, and whether "Encephalomyelitis, Autoimmune, Experimental" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2021 | 1 | 0 | 1 | 2019 | 0 | 2 | 2 | 2014 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2012 | 2 | 0 | 2 | 2009 | 3 | 1 | 4 | 2007 | 0 | 1 | 1 | 2004 | 2 | 0 | 2 | 2003 | 0 | 1 | 1 | 2002 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in Profiles over the past ten years.
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Candadai AA, Liu F, Fouda AY, Alfarhan M, Palani CD, Xu Z, Caldwell RB, Narayanan SP. Deletion of arginase 2 attenuates neuroinflammation in an experimental model of optic neuritis. PLoS One. 2021; 16(3):e0247901.
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Palani CD, Fouda AY, Liu F, Xu Z, Mohamed E, Giri S, Smith SB, Caldwell RB, Narayanan SP. Deletion of Arginase 2 Ameliorates Retinal Neurodegeneration in a Mouse Model of Multiple Sclerosis. Mol Neurobiol. 2019 Dec; 56(12):8589-8602.
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Cho JJ, Xu Z, Parthasarathy U, Drashansky TT, Helm EY, Zuniga AN, Lorentsen KJ, Mansouri S, Cho JY, Edelmann MJ, Duong DM, Gehring T, Seeholzer T, Krappmann D, Uddin MN, Califano D, Wang RL, Jin L, Li H, Lv D, Zhou D, Zhou L, Avram D. Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation. Nat Commun. 2019 02 11; 10(1):701.
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Mangan PR, Su LJ, Jenny V, Tatum AL, Picarillo C, Skala S, Ditto N, Lin Z, Yang X, Cotter PZ, Shuster DJ, Song Y, Borowski V, Thomas RL, Heimrich EM, Devaux B, Das Gupta R, Carvajal I, McIntyre KW, Xie J, Zhao Q, Struthers M, Salter-Cid LM. Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity. J Pharmacol Exp Ther. 2015 Aug; 354(2):152-65.
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