Multiple Sclerosis
"Multiple Sclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Descriptor ID |
D009103
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MeSH Number(s) |
C10.114.375.500 C10.314.350.500 C20.111.258.250.500
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Concept/Terms |
Multiple Sclerosis- Multiple Sclerosis
- Sclerosis, Multiple
- Sclerosis, Disseminated
- Disseminated Sclerosis
- MS (Multiple Sclerosis)
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Below are MeSH descriptors whose meaning is more general than "Multiple Sclerosis".
Below are MeSH descriptors whose meaning is more specific than "Multiple Sclerosis".
This graph shows the total number of publications written about "Multiple Sclerosis" by people in UAMS Profiles by year, and whether "Multiple Sclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2024 | 0 | 1 | 1 | 2022 | 2 | 0 | 2 | 2021 | 4 | 0 | 4 | 2019 | 1 | 1 | 2 | 2016 | 1 | 0 | 1 | 2013 | 4 | 0 | 4 | 2012 | 2 | 0 | 2 | 2006 | 1 | 1 | 2 | 2005 | 2 | 0 | 2 | 2003 | 4 | 0 | 4 | 2002 | 2 | 0 | 2 | 2000 | 0 | 1 | 1 | 1995 | 1 | 0 | 1 | 1994 | 0 | 1 | 1 |
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Below are the most recent publications written about "Multiple Sclerosis" by people in Profiles over the past ten years.
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Duque C, Mahinrad S, Sedaghat S, Higgins J, Milstead A, Sargento-Freitas J, Balabanov R, Cohen B, Sorond FA. Cerebrovascular hemodynamics association with brain structure and function in Multiple Sclerosis. Mult Scler Relat Disord. 2024 Nov; 91:105882.
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Ashrafzadeh-Kian S, Figdore D, Larson B, Deters R, Abou-Diwan C, Bornhorst J, Algeciras-Schimnich A. Head-to-head comparison of four plasma neurofilament light chain (NfL) immunoassays. Clin Chim Acta. 2024 Jul 15; 561:119817.
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Wotipka E, Mortensen P, Charoenkijkajorn C, Pakravan M, Lee AG. Apraxia of lid opening in multiple sclerosis. Can J Ophthalmol. 2023 06; 58(3):e139-e141.
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Sidarous GK, Roy AM, Sasapu A. Acquired Hemophilia A in a Patient With Multiple Sclerosis. Perm J. 2022 06 29; 26(2):153-157.
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Pike AR, James GA, Drew PD, Archer RL. Neuroimaging predictors of longitudinal disability and cognition outcomes in multiple sclerosis patients: A systematic review and meta-analysis. Mult Scler Relat Disord. 2022 Jan; 57:103452.
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Chauhan MZ, Chacko JG, Phillips PH, Siddiqui MZ, Uwaydat SH. Association of Acute Zonal Occult Outer Retinopathy With Multiple Sclerosis: A Report of 2 Cases. J Neuroophthalmol. 2022 03 01; 42(1):e377-e380.
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Chacko JA, Strati P, Stout PW, Archer RL, Baltz BP, Chacko JG. Primary mediastinal large B-cell lymphoma in a patient on Fingolimod for relapsing-remitting multiple sclerosis. Mult Scler Relat Disord. 2021 Apr; 49:102776.
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Erramuzpe A, Schurr R, Yeatman JD, Gotlib IH, Sacchet MD, Travis KE, Feldman HM, Mezer AA. A Comparison of Quantitative R1 and Cortical Thickness in Identifying Age, Lifespan Dynamics, and Disease States of the Human Cortex. Cereb Cortex. 2021 01 05; 31(2):1211-1226.
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Vattoth S, Kadam GH, Gaddikeri S. Revised McDonald Criteria, MAGNIMS Consensus and Other Relevant Guidelines for Diagnosis and Follow Up of MS: What Radiologists Need to Know? Curr Probl Diagn Radiol. 2021 May-Jun; 50(3):389-400.
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Palani CD, Fouda AY, Liu F, Xu Z, Mohamed E, Giri S, Smith SB, Caldwell RB, Narayanan SP. Deletion of Arginase 2 Ameliorates Retinal Neurodegeneration in a Mouse Model of Multiple Sclerosis. Mol Neurobiol. 2019 Dec; 56(12):8589-8602.
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Cho JJ, Xu Z, Parthasarathy U, Drashansky TT, Helm EY, Zuniga AN, Lorentsen KJ, Mansouri S, Cho JY, Edelmann MJ, Duong DM, Gehring T, Seeholzer T, Krappmann D, Uddin MN, Califano D, Wang RL, Jin L, Li H, Lv D, Zhou D, Zhou L, Avram D. Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation. Nat Commun. 2019 02 11; 10(1):701.
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Mock DM. Biotin: From Nutrition to Therapeutics. J Nutr. 2017 08; 147(8):1487-1492.
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Torres C, Hogan M, Patro S, Chakraborty S, Nguyen T, Thornhill R, Freedman M, Bussiere M, Dabirzadeh H, Schwarz BA, Belanger S, Legault-Kingstone L, Schweitzer M, Lum C. Extracranial Venous abnormalities: A true pathological finding in patients with multiple sclerosis or an anatomical variant? Eur Radiol. 2017 Jan; 27(1):239-246.
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Peyro Saint Paul L, Debruyne D, Bernard D, Mock DM, Defer GL. Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis. Expert Opin Drug Metab Toxicol. 2016; 12(3):327-44.
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Stuifbergen AK, Blozis S, Becker H, Harrison T, Kullberg V. Selected health behaviors moderate the progression of functional limitations in persons with multiple sclerosis: Eleven years of annual?follow-up. Disabil Health J. 2016 07; 9(3):472-8.
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