A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)

Descriptor ID	D000584
MeSH Number(s)	D03.383.679.149
Concept/Terms	Amiloride Amiloride Amiduret Trom Amiduret Trom Trom, Amiduret Trommsdorff Brand of Amiloride Hydrochloride Amiloberag Amiloberag Berolina Brand of Amiloride Hydrochloride Midoride Midoride Amrad Brand of Amiloride Hydrochloride Amiloride Hydrochloride, Anhydrous Amiloride Hydrochloride, Anhydrous Anhydrous Amiloride Hydrochloride Hydrochloride, Anhydrous Amiloride Kaluril Kaluril Alphapharm Brand of Amiloride Hydrochloride Midamor Midamor Modamide Merck Sharp & Dohme Brand of Amiloride Hydrochloride Cahill May Roberts Brand of Amiloride Hydrochloride Merck Brand of Amiloride Hydrochloride Amidal Amidal Douglas Brand of Amiloride Hydrochloride Amiloride Hydrochloride Amiloride Hydrochloride Hydrochloride, Amiloride

Below are MeSH descriptors whose meaning is more general than "Amiloride".

Below are MeSH descriptors whose meaning is related to "Amiloride".

Below are MeSH descriptors whose meaning is more specific than "Amiloride".