 Acetylcholinesterase
"Acetylcholinesterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.
| Descriptor ID |
D000110
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| MeSH Number(s) |
D08.811.277.352.100.170.176
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acetylcholinesterase".
Below are MeSH descriptors whose meaning is more specific than "Acetylcholinesterase".
This graph shows the total number of publications written about "Acetylcholinesterase" by people in UAMS Profiles by year, and whether "Acetylcholinesterase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 2 | 2 | | 2017 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 | | 2006 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2002 | 2 | 0 | 2 | | 1999 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1996 | 2 | 0 | 2 | | 1992 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetylcholinesterase" by people in Profiles over the past ten years.
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Alshehri S, Imam SS. Rosinidin Attenuates Lipopolysaccharide-Induced Memory Impairment in Rats: Possible Mechanisms of Action Include Antioxidant and Anti-Inflammatory Effects. Biomolecules. 2021 11 23; 11(12).
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Bowroju SK, Penthala NR, Lakkaniga NR, Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ, Crooks PA. Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease. Bioorg Med Chem. 2021 09 01; 45:116311.
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Moo LR, Martinez E, Padala K, Dunay MA, Scali RR, Chen S, Thielke SM. Unexpected Findings During Double-blind Discontinuation of Acetylcholinesterase Inhibitor Medications. Clin Ther. 2021 06; 43(6):942-952.
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Nazim M, Masuda A, Rahman MA, Nasrin F, Takeda JI, Ohe K, Ohkawara B, Ito M, Ohno K. Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms. Nucleic Acids Res. 2017 02 17; 45(3):1455-1468.
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Wang W, Qin Z, Zhu D, Wei Y, Li S, Duan L. Synthesis, Bioactivity Evaluation, and Toxicity Assessment of Novel Salicylanilide Ester Derivatives as Cercaricides against Schistosoma japonicum and Molluscicides against Oncomelania hupensis. Antimicrob Agents Chemother. 2016 01; 60(1):323-31.
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Rahman MA, Azuma Y, Nasrin F, Takeda J, Nazim M, Bin Ahsan K, Masuda A, Engel AG, Ohno K. SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndrome. Sci Rep. 2015 Aug 18; 5:13208.
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