 RNA Splicing
"RNA Splicing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ultimate exclusion of nonsense sequences or intervening sequences (introns) before the final RNA transcript is sent to the cytoplasm.
| Descriptor ID |
D012326
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| MeSH Number(s) |
G02.111.087.750.700 G02.149.115.750.700 G03.495.839.700 G05.355.315.700.700
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| Concept/Terms |
RNA Splicing- RNA Splicing
- Splicing, RNA
- RNA Splicings
- Splicings, RNA
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Below are MeSH descriptors whose meaning is more general than "RNA Splicing".
Below are MeSH descriptors whose meaning is more specific than "RNA Splicing".
This graph shows the total number of publications written about "RNA Splicing" by people in UAMS Profiles by year, and whether "RNA Splicing" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 1 | 0 | 1 | | 2022 | 1 | 1 | 2 | | 2021 | 0 | 1 | 1 | | 2020 | 1 | 2 | 3 | | 2017 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2013 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1994 | 0 | 1 | 1 | | 1992 | 0 | 2 | 2 | | 1991 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "RNA Splicing" by people in Profiles over the past ten years.
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Islam MR, Nagar P, Neetole ST, Wan L, Rahman MA. RNA Splicing in Cancer and Targeted Therapies. Genes (Basel). 2023 10 29; 14(11).
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Chen PC, Han X, Shaw TI, Fu Y, Sun H, Niu M, Wang Z, Jiao Y, Teubner BJW, Eddins D, Beloate LN, Bai B, Mertz J, Li Y, Cho JH, Wang X, Wu Z, Liu D, Poudel S, Yuan ZF, Mancieri A, Low J, Lee HM, Patton MH, Earls LR, Stewart E, Vogel P, Hui Y, Wan S, Bennett DA, Serrano GE, Beach TG, Dyer MA, Smeyne RJ, Moldoveanu T, Chen T, Wu G, Zakharenko SS, Yu G, Peng J. Alzheimer's disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment. Nat Aging. 2022 10; 2(10):923-940.
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Gao Y, Lin KT, Jiang T, Yang Y, Rahman MA, Gong S, Bai J, Wang L, Sun J, Sheng L, Krainer AR, Hua Y. Systematic characterization of short intronic splicing-regulatory elements in SMN2 pre-mRNA. Nucleic Acids Res. 2022 01 25; 50(2):731-749.
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Bauer MA, Ashby C, Wardell C, Boyle EM, Ortiz M, Flynt E, Thakurta A, Morgan G, Walker BA. Differential RNA splicing as a potentially important driver mechanism in multiple myeloma. Haematologica. 2021 03 01; 106(3):736-745.
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Schultz-Rogers L, Masuho I, Pinto E Vairo F, Schmitz CT, Schwab TL, Clark KJ, Gunderson L, Pichurin PN, Wierenga K, Martemyanov KA, Klee EW. Haploinsufficiency as a disease mechanism in GNB1-associated neurodevelopmental disorder. Mol Genet Genomic Med. 2020 11; 8(11):e1477.
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Rahman MA, Lin KT, Bradley RK, Abdel-Wahab O, Krainer AR. Recurrent SRSF2 mutations in MDS affect both splicing and NMD. Genes Dev. 2020 03 01; 34(5-6):413-427.
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Rahman MA, Krainer AR, Abdel-Wahab O. SnapShot: Splicing Alterations in Cancer. Cell. 2020 01 09; 180(1):208-208.e1.
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Fausther M, G Lavoie E, Dranoff JA. Liver myofibroblasts of murine origins express mesothelin: Identification of novel rat mesothelin splice variants. PLoS One. 2017; 12(9):e0184499.
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Gu Z, Xia J, Xu H, Frech I, Tricot G, Zhan F. NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase. J Hematol Oncol. 2017 01 13; 10(1):17.
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Shibata A, Okuno T, Rahman MA, Azuma Y, Takeda J, Masuda A, Selcen D, Engel AG, Ohno K. IntSplice: prediction of the splicing consequences of intronic single-nucleotide variations in the human genome. J Hum Genet. 2016 Jul; 61(7):633-40.
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Bright MD, Itzhak DN, Wardell CP, Morgan GJ, Davies FE. Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress. Mol Cell Biol. 2015 Jun; 35(12):2186-202.
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