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University of Arkansas for Medical Sciences
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The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine.
Fan M, Goodwin ME, Birrer MJ, Chambers TC. The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine. Cancer Res. 2001 Jun 01; 61(11):4450-8.
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PubMed
subject areas
Activating Transcription Factor 2
Antineoplastic Agents, Phytogenic
Apoptosis
Cyclic AMP Response Element-Binding Protein
Cyclin-Dependent Kinase Inhibitor p21
Cyclins
Down-Regulation
Drug Resistance, Neoplasm
Gene Expression Regulation, Neoplastic
Humans
JNK Mitogen-Activated Protein Kinases
KB Cells
Mitogen-Activated Protein Kinases
Mitosis
Phosphorylation
Protein Structure, Tertiary
Signal Transduction
Transcription Factor AP-1
Transcription Factors
Transfection
Tumor Suppressor Protein p53
Vinblastine
authors with profiles
Michael Birrer