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G-Quadruplex loops regulate PARP-1 enzymatic activation.
Edwards AD, Marecki JC, Byrd AK, Gao J, Raney KD. G-Quadruplex loops regulate PARP-1 enzymatic activation. Nucleic Acids Res. 2021 01 11; 49(1):416-431.
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PubMed
subject areas
Catalysis
DNA Damage
Enzyme Activation
G-Quadruplexes
Guanine
Humans
Oxidation-Reduction
Promoter Regions, Genetic
Proto-Oncogene Proteins c-kit
Recombinant Proteins
Structure-Activity Relationship
Substrate Specificity
authors with profiles
Alicia Byrd
Kevin Raney
Jun Gao
John Marecki