The a?a? flavonoid velutin is a potent anti-inflammatory agent: blockade of LPS-mediated TNF-a and IL-6 production through inhibiting NF-?B activation and MAPK pathway.
Xie C, Kang J, Li Z, Schauss AG, Badger TM, Nagarajan S, Wu T, Wu X. The a?a? flavonoid velutin is a potent anti-inflammatory agent: blockade of LPS-mediated TNF-a and IL-6 production through inhibiting NF-?B activation and MAPK pathway. J Nutr Biochem. 2012 Sep; 23(9):1184-91.