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University of Arkansas for Medical Sciences
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4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas.
Sharma R, Sharma A, Dwivedi S, Zimniak P, Awasthi S, Awasthi YC. 4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas. Biochemistry. 2008 Jan 08; 47(1):143-56.
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PubMed
subject areas
Adaptor Proteins, Signal Transducing
Aldehydes
Anthracenes
Apoptosis
Blotting, Western
Caspase 3
Caspase 8
Cell Line
Cell Nucleus
Cell Survival
Co-Repressor Proteins
Cytosol
Death Domain Receptor Signaling Adaptor Proteins
DNA-Binding Proteins
Dose-Response Relationship, Drug
Fas Ligand Protein
HSP70 Heat-Shock Proteins
Humans
Immunoprecipitation
JNK Mitogen-Activated Protein Kinases
Jurkat Cells
MAP Kinase Kinase Kinase 5
Microscopy, Fluorescence
Models, Biological
Molecular Chaperones
Nuclear Proteins
Protein Transport
RNA, Small Interfering
Transcription Factors
authors with profiles
Piotr Zimniak