 Caspase 8
"Caspase 8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.
| Descriptor ID |
D053181
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| MeSH Number(s) |
D08.811.277.656.262.500.126.550.800 D08.811.277.656.300.200.126.550.800 D12.644.360.075.405.550.800 D12.776.476.075.405.550.800
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| Concept/Terms |
Caspase 8- Caspase 8
- MACH Protein
- Caspase-8
- FLICE Protein
- Mch5 Protease
- CAP4 Protease
Procaspase-8- Procaspase-8
- Procaspase 8
- Pro-Caspase-8
- Pro Caspase 8
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Below are MeSH descriptors whose meaning is more general than "Caspase 8".
Below are MeSH descriptors whose meaning is more specific than "Caspase 8".
This graph shows the total number of publications written about "Caspase 8" by people in UAMS Profiles by year, and whether "Caspase 8" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2006 | 0 | 2 | 2 | | 2005 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Caspase 8" by people in Profiles over the past ten years.
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Zhang Y, Liu C, Barbier O, Smalling R, Tsuchiya H, Lee S, Delker D, Zou A, Hagedorn CH, Wang L. Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function. Sci Rep. 2016 Feb 03; 6:20559.
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Mohamed RH, Karam RA, Hagrass HA, Amer MG, Abd El-Haleem MR. Anti-apoptotic effect of spermatogonial stem cells on doxorubicin-induced testicular toxicity in rats. Gene. 2015 Apr 25; 561(1):107-14.
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Haverkamp JM, Smith AM, Weinlich R, Dillon CP, Qualls JE, Neale G, Koss B, Kim Y, Bronte V, Herold MJ, Green DR, Opferman JT, Murray PJ. Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways. Immunity. 2014 Dec 18; 41(6):947-59.
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