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University of Arkansas for Medical Sciences
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Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter.
McConathy J, Owens MJ, Kilts CD, Malveaux EJ, Camp VM, Votaw JR, Nemeroff CB, Goodman MM. Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter. Nucl Med Biol. 2004 Aug; 31(6):705-18.
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PubMed
subject areas
Alkylation
Animals
Benzofurans
Binding, Competitive
Chromatography, High Pressure Liquid
Dopamine Plasma Membrane Transport Proteins
Indicators and Reagents
Ligands
Macaca mulatta
Male
Membrane Glycoproteins
Membrane Transport Proteins
Nerve Tissue Proteins
Norepinephrine Plasma Membrane Transport Proteins
Positron-Emission Tomography
Propylamines
Radiopharmaceuticals
Serotonin Plasma Membrane Transport Proteins
Spectrophotometry, Ultraviolet
Stereoisomerism
Symporters
Thiophenes
Tissue Distribution