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Sam Lee

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentCOM | Peds Cardiology
DivisionPeds Cardiology
Address4301 W. Markham
Mail Slot # 512-3
Little Rock AR 72205
ORCID ORCID Icon0009-0003-1209-8180 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Leasure JW, Lee SM, Yerlioglu KL, Castellon M, Li H, Fantauzzi A, Chen S, Muslmani SB, Sharma A, Chen J, Minshall RD. Transcriptomic profiling of the sex-linked biological pathways of severe pulmonary arterial hypertension associated with endothelial cell caveolin-1 depletion and chronic hypoxia. Front Physiol. 2026; 17:1794886. PMID: 42180844.
      View in: PubMed
    2. Hawro I, Lee SM, Kineman RD, Cordoba-Chacon J. PPAR?-dependent and -independent regulation of methionine metabolism by diet-induced obesity and fasting in male mice. bioRxiv. 2026 Mar 27. PMID: 41929038.
      View in: PubMed
    3. Sierra-Cruz M, Hawro I, Lee SM, Muratalla J, Cordoba-Chacon J. Sex- and hepatocyte PPAR?-dependent effects of an obesogenic dietary approach to induce MASH with fibrosis in mice. bioRxiv. 2026 Mar 16. PMID: 41889940.
      View in: PubMed
    4. Isbatan A, Lee SM, Sarwar AI, Yuan Y, Chen S, Castellon M, Marian DA, Minshall RD, Tian J, Levitan I, Chen J. Age-Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice. Pediatr Discov. 2026 Mar; 4(1):e2525. PMID: 42021960.
      View in: PubMed
    5. Song Q, Hwang CL, Li Y, Wang J, Park J, Lee SM, Sun Z, Sun J, Xia Y, Nieto N, Cordoba-Chacon J, Jiang Y, Dou X, Song Z. Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis activation. Metabolism. 2024 Feb; 151:155740. PMID: 37995805.
      View in: PubMed
    6. Song Q, Wang J, Griffiths A, Lee SM, Iyamu ID, Huang R, Cordoba-Chacon J, Song Z. Nicotinamide N-methyltransferase upregulation contributes to palmitate-elicited peroxisome proliferator-activated receptor transactivation in hepatocytes. Am J Physiol Cell Physiol. 2023 07 01; 325(1):C29-C41. PMID: 37212549.
      View in: PubMed
    7. Lee SM, Muratalla J, Sierra-Cruz M, Cordoba-Chacon J. Role of hepatic peroxisome proliferator-activated receptor ? in non-alcoholic fatty liver disease. J Endocrinol. 2023 04 01; 257(1). PMID: 36688873.
      View in: PubMed
    8. Griffiths A, Wang J, Song Q, Lee SM, Cordoba-Chacon J, Song Z. ATF4-mediated CD36 upregulation contributes to palmitate-induced lipotoxicity in hepatocytes. Am J Physiol Gastrointest Liver Physiol. 2023 05 01; 324(5):G341-G353. PMID: 36852918.
      View in: PubMed
    9. Lee SM, Muratalla J, Karimi S, Diaz-Ruiz A, Frutos MD, Guzman G, Ramos-Molina B, Cordoba-Chacon J. Hepatocyte PPAR? contributes to the progression of non-alcoholic steatohepatitis in male and female obese mice. Cell Mol Life Sci. 2023 Jan 11; 80(2):39. PMID: 36629912.
      View in: PubMed
    10. Lee SM, Muratalla J, Diaz-Ruiz A, Remon-Ruiz P, McCann M, Liew CW, Kineman RD, Cordoba-Chacon J. Rosiglitazone Requires Hepatocyte PPAR? Expression to Promote Steatosis in Male Mice With Diet-Induced Obesity. Endocrinology. 2021 11 01; 162(11). PMID: 34417811.
      View in: PubMed
    11. Lee SM, Pusec CM, Norris GH, De Jesus A, Diaz-Ruiz A, Muratalla J, Sarmento-Cabral A, Guzman G, Layden BT, Cordoba-Chacon J. Hepatocyte-Specific Loss of PPAR? Protects Mice From NASH and Increases the Therapeutic Effects of Rosiglitazone in the Liver. Cell Mol Gastroenterol Hepatol. 2021; 11(5):1291-1311. PMID: 33444819.
      View in: PubMed
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