 Insulin Resistance
"Insulin Resistance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Descriptor ID |
D007333
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| MeSH Number(s) |
C18.452.394.968.500 G07.690.320.617
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Insulin Resistance".
Below are MeSH descriptors whose meaning is more specific than "Insulin Resistance".
This graph shows the total number of publications written about "Insulin Resistance" by people in UAMS Profiles by year, and whether "Insulin Resistance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 3 | 2 | 5 | | 2023 | 1 | 0 | 1 | | 2022 | 5 | 0 | 5 | | 2021 | 4 | 2 | 6 | | 2020 | 2 | 2 | 4 | | 2019 | 2 | 3 | 5 | | 2018 | 3 | 1 | 4 | | 2017 | 2 | 4 | 6 | | 2016 | 5 | 3 | 8 | | 2015 | 5 | 2 | 7 | | 2014 | 2 | 1 | 3 | | 2013 | 8 | 4 | 12 | | 2012 | 3 | 6 | 9 | | 2011 | 2 | 5 | 7 | | 2010 | 6 | 9 | 15 | | 2009 | 2 | 3 | 5 | | 2008 | 2 | 1 | 3 | | 2007 | 7 | 5 | 12 | | 2006 | 6 | 3 | 9 | | 2005 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2003 | 2 | 0 | 2 | | 2001 | 1 | 2 | 3 | | 2000 | 1 | 1 | 2 | | 1999 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 |
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Below are the most recent publications written about "Insulin Resistance" by people in Profiles over the past ten years.
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Wyler SC, Gahlot S, Bideyan L, Yip C, Dushime J, Chen B, Lee JJ, Tinajero A, Limboy C, Bordash S, Heaselgrave SR, Nguyen TN, Lee S, Bookout A, Lantier L, Fowlkes JL, You YJ, Fujikawa T, Elmquist JK. LCoRL Regulates Growth and Metabolism. Endocrinology. 2024 Oct 30; 165(12).
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Pinho ACO, Barbosa P, Lazaro A, Tralh?o JG, Pereira MJ, Paiva A, Laranjeira P, Carvalho E. Identification and characterization of circulating and adipose tissue infiltrated CD20+T cells from subjects with obesity that undergo bariatric surgery. Immunol Lett. 2024 10; 269:106911.
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Park S, Cha HN, Shin MG, Park S, Kim Y, Kim MS, Shin KH, Thoudam T, Lee EJ, Wolfe RR, Dan J, Koh JH, Kim IY, Choi I, Lee IK, Sung HK, Park SY. Inhibitory Regulation of FOXO1 in PPARd Expression Drives Mitochondrial Dysfunction and Insulin Resistance. Diabetes. 2024 Jul 01; 73(7):1084-1098.
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Fordham TM, Morelli NS, Garcia-Reyes Y, Ware MA, Rahat H, Sundararajan D, Fuller KNZ, Severn C, Pyle L, Malloy CR, Jin ES, Parks EJ, Wolfe RR, Cree MG. Metabolic effects of an essential amino acid supplement in adolescents with PCOS and obesity. Obesity (Silver Spring). 2024 04; 32(4):678-690.
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Pinho ACO, Laranjeira P, Carvalho E. Role of CD20+ T cells in cancer, autoimmunity and obesity. J Endocrinol. 2024 03 01; 260(3).
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Hulett NA, Knaub LA, Hull SE, Pott GB, Peelor R, Miller BF, Shankar K, Rudolph MC, Reusch JEB, Scalzo RL. Sex Differences in the Skeletal Muscle Response to a High Fat, High Sucrose Diet in Rats. Nutrients. 2023 Oct 19; 15(20).
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Santos D, Porter-Gill P, Goode G, Delhey L, S?rensen AE, Rose S, B?rsheim E, Dalgaard LT, Carvalho E. Circulating microRNA levels differ in the early stages of insulin resistance in prepubertal children with obesity. Life Sci. 2023 Jan 01; 312:121246.
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Jang J, Koh JH, Kim Y, Kim HJ, Park S, Chang Y, Jung J, Wolfe RR, Kim IY. Balanced Free Essential Amino Acids and Resistance Exercise Training Synergistically Improve Dexamethasone-Induced Impairments in Muscle Strength, Endurance, and Insulin Sensitivity in Mice. Int J Mol Sci. 2022 Aug 27; 23(17).
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Barbosa P, Landes RD, Graw S, Byrum SD, Bennuri S, Delhey L, Randolph C, MacLeod S, Reis A, B?rsheim E, Rose S, Carvalho E. Effect of excess weight and insulin resistance on DNA methylation in prepubertal children. Sci Rep. 2022 05 19; 12(1):8430.
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Li Y, Talbot CL, Chandravanshi B, Ksiazek A, Sood A, Chowdhury KH, Maschek JA, Cox J, Babu AKS, Paz HA, Babu PVA, Meyerholz DK, Wankhade UD, Holland W, Shyong Tai E, Summers SA, Chaurasia B. Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis. Sci Rep. 2022 05 04; 12(1):7273.
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Lin H, Mercer KE, Ou X, Mansfield K, Buchmann R, B?rsheim E, Tas E. Circulating microRNAs Are Associated With Metabolic Markers in Adolescents With Hepatosteatosis. Front Endocrinol (Lausanne). 2022; 13:856973.
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Diaz EC, Weber JL, Adams SH, Young CG, Bai S, B?rsheim E. Cardiorespiratory Fitness Associates with Blood Pressure and Metabolic Health of Children-The Arkansas Active Kids Study. Med Sci Sports Exerc. 2021 11 01; 53(11):2225-2232.
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Cohen CC, Perng W, Sundaram SS, Scherzinger A, Shankar K, Dabelea D. Hepatic Fat in Early Childhood Is Independently Associated With Estimated Insulin Resistance: The Healthy Start Study. J Clin Endocrinol Metab. 2021 10 21; 106(11):3140-3150.
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Watson KT, Simard JF, Henderson VW, Nutkiewicz L, Lamers F, Nasca C, Rasgon N, Penninx BWJH. Incident Major Depressive Disorder Predicted by Three Measures of Insulin Resistance: A Dutch Cohort Study. Am J Psychiatry. 2021 10 01; 178(10):914-920.
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Watson KT, Simard JF, Henderson VW, Nutkiewicz L, Lamers F, Rasgon N, Penninx B. Association of Insulin Resistance With Depression Severity and Remission Status: Defining a Metabolic Endophenotype of Depression. JAMA Psychiatry. 2021 04 01; 78(4):439-441.
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Mercer KE, Maurer A, Pack LM, Ono-Moore K, Spray BJ, Campbell C, Chandler CJ, Burnett D, Souza E, Casazza G, Keim N, Newman J, Hunter G, Fernadez J, Garvey WT, Harper ME, Hoppel C, Adams SH, Thyfault J. Exercise training and diet-induced weight loss increase markers of hepatic bile acid (BA) synthesis and reduce serum total BA concentrations in obese women. Am J Physiol Endocrinol Metab. 2021 05 01; 320(5):E864-E873.
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Allman BR, Spray BJ, Mercer KE, Andres A, B?rsheim E. Markers of branched-chain amino acid catabolism are not affected by exercise training in pregnant women with obesity. J Appl Physiol (1985). 2021 03 01; 130(3):651-659.
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Kim IY, Park S, Kim Y, Chang Y, Choi CS, Suh SH, Wolfe RR. In Vivo and In Vitro Quantification of Glucose Kinetics: From Bedside to Bench. Endocrinol Metab (Seoul). 2020 12; 35(4):733-749.
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Grapov D, Fiehn O, Campbell C, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Keim NL, Hunter GR, Fernandez JR, Garvey WT, Hoppel CL, Harper ME, Newman JW, Adams SH. Impact of a weight loss and fitness intervention on exercise-associated plasma oxylipin patterns in obese, insulin-resistant, sedentary women. Physiol Rep. 2020 09; 8(17):e14547.
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Maurer A, Ward JL, Dean K, Billinger SA, Lin H, Mercer KE, Adams SH, Thyfault JP. Divergence in aerobic capacity impacts bile acid metabolism in young women. J Appl Physiol (1985). 2020 10 01; 129(4):768-778.
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Blackburn ML, Ono-Moore KD, Sobhi HF, Adams SH. Carnitine palmitoyltransferase 2 knockout potentiates palmitate-induced insulin resistance in C2C12 myotubes. Am J Physiol Endocrinol Metab. 2020 08 01; 319(2):E265-E275.
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Allman BR, Williams DK, B?rsheim E, Andres A. Dietary Protein Intake during Pregnancy Is Not Associated with Offspring Insulin Sensitivity during the First Two Years of Life. Nutrients. 2020 May 08; 12(5).
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Davidson CQ, Tharmalingam S, Niccoli S, Nemec-Bakk A, Khurana S, Murray A, Tai TC, Boreham DR, Khaper N, Lees SJ. Dose threshold for radiation induced fetal programming in a mouse model at 4 months of age: Hepatic expression of genes and proteins involved in glucose metabolism and glucose uptake in brown adipose tissue. PLoS One. 2020; 15(4):e0231650.
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de Conti A, Tryndyak V, Willett RA, Borowa-Mazgaj B, Watson A, Patton R, Khare S, Muskhelishvili L, Olson GR, Avigan MI, Cerniglia CE, Ross SA, Sanyal AJ, Beland FA, Rusyn I, Pogribny IP. Characterization of the variability in the extent of nonalcoholic fatty liver induced by a high-fat diet in the genetically diverse Collaborative Cross mouse model. FASEB J. 2020 06; 34(6):7773-7785.
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Lowry JE, Tumurbaatar B, D'Agostino C, Main E, Wright TJ, Dillon EL, Saito TB, Porter C, Andersen CR, Brining DL, Endsley JJ, Sheffield-Moore M, Volpi E, Fang R, Abate N, Tuvdendorj DR. Effect of high-fat diet on peripheral blood mononuclear cells and adipose tissue in early stages of diet-induced weight gain. Br J Nutr. 2019 12 28; 122(12):1359-1367.
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Solverson PM, Henderson TR, Debelo H, Ferruzzi MG, Baer DJ, Novotny JA. An Anthocyanin-Rich Mixed-Berry Intervention May Improve Insulin Sensitivity in a Randomized Trial of Overweight and Obese Adults. Nutrients. 2019 Nov 25; 11(12).
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Najjar RS, Feresin RG. Plant-Based Diets in the Reduction of Body Fat: Physiological Effects and Biochemical Insights. Nutrients. 2019 Nov 08; 11(11).
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Allman BR, Diaz Fuentes E, Williams DK, Turner DE, Andres A, B?rsheim E. Obesity Status Affects the Relationship Between Protein Intake and Insulin Sensitivity in Late Pregnancy. Nutrients. 2019 Sep 11; 11(9).
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Diaz EC, B?rsheim E, Shankar K, Cleves MA, Andres A. Prepregnancy Fat Free Mass and Associations to Glucose Metabolism Before and During Pregnancy. J Clin Endocrinol Metab. 2019 05 01; 104(5):1394-1403.
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Morris EM, Meers GME, Ruegsegger GN, Wankhade UD, Robinson T, Koch LG, Britton SL, Rector RS, Shankar K, Thyfault JP. Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance. Endocrinology. 2019 05 01; 160(5):1179-1192.
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Kulas JA, Franklin WF, Smith NA, Manocha GD, Puig KL, Nagamoto-Combs K, Hendrix RD, Taglialatela G, Barger SW, Combs CK. Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues. Am J Physiol Endocrinol Metab. 2019 01 01; 316(1):E106-E120.
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Clayton RP, Herndon DN, Abate N, Porter C. The Effect of Burn Trauma on Lipid and Glucose Metabolism: Implications for Insulin Sensitivity. J Burn Care Res. 2018 08 17; 39(5):713-723.
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Solverson PM, Rumpler WV, Leger JL, Redan BW, Ferruzzi MG, Baer DJ, Castonguay TW, Novotny JA. Blackberry Feeding Increases Fat Oxidation and Improves Insulin Sensitivity in Overweight and Obese Males. Nutrients. 2018 Aug 09; 10(8).
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D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC. Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. J Lipid Res. 2018 10; 59(10):1805-1817.
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Krishnan S, Adams SH, Allen LH, Laugero KD, Newman JW, Stephensen CB, Burnett DJ, Witbracht M, Welch LC, Que ES, Keim NL. A randomized controlled-feeding trial based on the Dietary Guidelines for Americans on cardiometabolic health indexes. Am J Clin Nutr. 2018 08 01; 108(2):266-278.
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Park YM, Choi MK, Lee SS, Shivappa N, Han K, Steck SE, H?bert JR, Merchant AT, Sandler DP. Dietary inflammatory potential and risk of mortality in metabolically healthy and unhealthy phenotypes among overweight and obese adults. Clin Nutr. 2019 04; 38(2):682-688.
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Arroyo E, Wells AJ, Gordon JA, Varanoske AN, Gepner Y, Coker NA, Church DD, Fukuda DH, Stout JR, Hoffman JR. Tumor necrosis factor-alpha and soluble TNF-alpha receptor responses in young vs. middle-aged males following eccentric exercise. Exp Gerontol. 2017 12 15; 100:28-35.
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Stuart CA, Lee ML, South MA, Howell MEA, Stone MH. Muscle hypertrophy in prediabetic men after 16 wk of resistance training. J Appl Physiol (1985). 2017 Oct 01; 123(4):894-901.
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Burgeiro A, Cerqueira MG, Varela-Rodr?guez BM, Nunes S, Neto P, Pereira FC, Reis F, Carvalho E. Glucose and Lipid Dysmetabolism in a Rat Model of Prediabetes Induced by a High-Sucrose Diet. Nutrients. 2017 Jun 21; 9(6).
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Gangadhariah MH, Dieckmann BW, Lantier L, Kang L, Wasserman DH, Chiusa M, Caskey CF, Dickerson J, Luo P, Gamboa JL, Capdevila JH, Imig JD, Yu C, Pozzi A, Luther JM. Cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids contribute to insulin sensitivity in mice and in humans. Diabetologia. 2017 06; 60(6):1066-1075.
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Park YM, Zhang J, Steck SE, Fung TT, Hazlett LJ, Han K, Ko SH, Merchant AT. Obesity Mediates the Association between Mediterranean Diet Consumption and Insulin Resistance and Inflammation in US Adults. J Nutr. 2017 04; 147(4):563-571.
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Chan KL, Tam TH, Boroumand P, Prescott D, Costford SR, Escalante NK, Fine N, Tu Y, Robertson SJ, Prabaharan D, Liu Z, Bilan PJ, Salter MW, Glogauer M, Girardin SE, Philpott DJ, Klip A. Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance. Cell Rep. 2017 03 07; 18(10):2415-2426.
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Bloom K, Mohsen AW, Karunanidhi A, El Demellawy D, Reyes-M?gica M, Wang Y, Ghaloul-Gonzalez L, Otsubo C, Tobita K, Muzumdar R, Gong Z, Tas E, Basu S, Chen J, Bennett M, Hoppel C, Vockley J. Investigating the link of ACAD10 deficiency to type 2 diabetes mellitus. J Inherit Metab Dis. 2018 01; 41(1):49-57.
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Zhang J, Light AR, Hoppel CL, Campbell C, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Hughen RW, Keim NL, Newman JW, Hunter GR, Fernandez JR, Garvey WT, Harper ME, Fiehn O, Adams SH. Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons. Exp Physiol. 2017 01 01; 102(1):48-69.
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Garc?a-Casarrubios E, de Moura C, Arroba AI, Pescador N, Calderon-Dominguez M, Garcia L, Herrero L, Serra D, Cadenas S, Reis F, Carvalho E, Obregon MJ, Valverde ?M. Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes. Biochim Biophys Acta. 2016 12; 1861(12 Pt A):1929-1941.
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Barazzoni R, Deutz NEP, Biolo G, Bischoff S, Boirie Y, Cederholm T, Cuerda C, Delzenne N, Leon Sanz M, Ljungqvist O, Muscaritoli M, Pichard C, Preiser JC, Sbraccia P, Singer P, Tappy L, Thorens B, Van Gossum A, Vettor R, Calder PC. Carbohydrates and insulin resistance in clinical nutrition: Recommendations from the ESPEN expert group. Clin Nutr. 2017 04; 36(2):355-363.
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Park YM, Steck SE, Fung TT, Zhang J, Hazlett LJ, Han K, Lee SH, Kwon HS, Merchant AT. Mediterranean diet, Dietary Approaches to Stop Hypertension (DASH) style diet, and metabolic health in U.S. adults. Clin Nutr. 2017 10; 36(5):1301-1309.
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Song IS, Han K, Park YM, Ji S, Jun SH, Ryu JJ, Park JB. Severe Periodontitis Is Associated with Insulin Resistance in Non-abdominal Obese Adults. J Clin Endocrinol Metab. 2016 11; 101(11):4251-4259.
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Eguchi A, Lazic M, Armando AM, Phillips SA, Katebian R, Maraka S, Quehenberger O, Sears DD, Feldstein AE. Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress. J Mol Med (Berl). 2016 11; 94(11):1241-1253.
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Heard ME, Melnyk SB, Simmen FA, Yang Y, Pabona JM, Simmen RC. High-Fat Diet Promotion of Endometriosis in an Immunocompetent Mouse Model is Associated With Altered Peripheral and Ectopic Lesion Redox and Inflammatory Status. Endocrinology. 2016 07; 157(7):2870-82.
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Yun KJ, Han K, Kim MK, Park YM, Baek KH, Song KH, Kwon HS. Insulin Resistance Distribution and Cut-Off Value in Koreans from the 2008-2010 Korean National Health and Nutrition Examination Survey. PLoS One. 2016; 11(4):e0154593.
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de Matos MA, Duarte TC, Ottone Vde O, Sampaio PF, Costa KB, de Oliveira MF, Moseley PL, Schneider SM, Coimbra CC, Brito-Melo GE, Magalh?es Fde C, Amorim FT, Rocha-Vieira E. The effect of insulin resistance and exercise on the percentage of CD16(+) monocyte subset in obese individuals. Cell Biochem Funct. 2016 Jun; 34(4):209-16.
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Kirby TJ, Walton RG, Finlin B, Zhu B, Unal R, Rasouli N, Peterson CA, Kern PA. Integrative mRNA-microRNA analyses reveal novel interactions related to insulin sensitivity in human adipose tissue. Physiol Genomics. 2016 Feb; 48(2):145-53.
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Lee SH, Rhee M, Yang HK, Ha HS, Lee JH, Kwon HS, Park YM, Yim HW, Kang MI, Lee WC, Son HY, Yoon KH. Serum preadipocyte factor 1 concentrations and risk of developing diabetes: a nested case-control study. Diabet Med. 2016 May; 33(5):631-8.
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