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Endothelin-1 upregulation mediates aging-related cardiac fibrosis.
Wang X, Guo Z, Ding Z, Khaidakov M, Lin J, Xu Z, Sharma SG, Jiwani S, Mehta JL. Endothelin-1 upregulation mediates aging-related cardiac fibrosis. J Mol Cell Cardiol. 2015 Mar; 80:101-9.
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PubMed
subject areas
Aging
Animals
Aspartic Acid Endopeptidases
beta-Galactosidase
Endothelin-1
Enzyme Activation
Estrogen Receptor alpha
Female
Fibroblasts
Fibrosis
Gene Expression Regulation
Gene Knockdown Techniques
Humans
Metalloendopeptidases
Mice
Myocardium
RNA Interference
Signal Transduction
Up-Regulation
authors with profiles
Jawahar Mehta
Shree Sharma