 Endothelin-1
"Endothelin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
| Descriptor ID |
D019332
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| MeSH Number(s) |
D12.644.276.400.225 D12.776.467.400.225 D23.529.400.225
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| Concept/Terms |
Endothelin-1- Endothelin-1
- Endothelin 1
- Endothelin Type 1
- ET-1 (Endothelin-1)
Proendothelin (1-38)- Proendothelin (1-38)
- Big Endothelin
- Big Endothelin-1
- Big Endothelin 1
- Endothelin-1, Big
- Endothelin, Big
Preproendothelin-1- Preproendothelin-1
- Preproendothelin 1
- Preproendothelin
- Proendothelin-1 Precursor
- Precursor, Proendothelin-1
- Proendothelin 1 Precursor
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Below are MeSH descriptors whose meaning is more general than "Endothelin-1".
Below are MeSH descriptors whose meaning is more specific than "Endothelin-1".
This graph shows the total number of publications written about "Endothelin-1" by people in UAMS Profiles by year, and whether "Endothelin-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2007 | 1 | 3 | 4 | | 2006 | 2 | 0 | 2 | | 2005 | 2 | 1 | 3 | | 2004 | 3 | 0 | 3 | | 2002 | 1 | 2 | 3 | | 1996 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Endothelin-1" by people in Profiles over the past ten years.
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Rezaei M, Mehta JL, Zadeh GM, Khedri A, Rezaei HB. Myosin light chain phosphatase is a downstream target of Rho-kinase in endothelin-1-induced transactivation of the TGF-? receptor. Cell Biochem Biophys. 2024 Jun; 82(2):1109-1120.
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Babaahmadi-Rezaei H, Rezaei M, Ghaderi-Zefrehi H, Azizi M, Beheshti-Nasab H, Mehta JL. Reducing Proteoglycan Synthesis and NOX Activity by ROCK Inhibitors: Therapeutic Targets in Atherosclerosis. Endocr Metab Immune Disord Drug Targets. 2022; 22(12):1191-1200.
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Yammine L, Frazier L, Padhye NS, Sanner JE, Burg MM. Two-year prognosis after acute coronary syndrome in younger patients: Association with feeling depressed in the prior year, and BDI-II score and Endothelin-1. J Psychosom Res. 2017 08; 99:8-12.
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Lai H, Stitzer M, Treisman G, Moore R, Brinker J, Gerstenblith G, Kickler TS, Li J, Chen S, Fishman E, Lai S. Cocaine Abstinence and Reduced Use Associated With Lowered Marker of Endothelial Dysfunction in African Americans: A Preliminary Study. J Addict Med. 2015 Jul-Aug; 9(4):331-9.
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Wang X, Guo Z, Ding Z, Khaidakov M, Lin J, Xu Z, Sharma SG, Jiwani S, Mehta JL. Endothelin-1 upregulation mediates aging-related cardiac fibrosis. J Mol Cell Cardiol. 2015 Mar; 80:101-9.
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