 Endocrine Disruptors
"Endocrine Disruptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
| Descriptor ID |
D052244
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| MeSH Number(s) |
D27.505.696.353 D27.888.284.295
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| Concept/Terms |
Endocrine Disruptors- Endocrine Disruptors
- Disruptors, Endocrine
- Endocrine Disrupting Chemicals
- Chemicals, Endocrine Disrupting
Endocrine Disruptor Effect- Endocrine Disruptor Effect
- Disruptor Effect, Endocrine
- Effect, Endocrine Disruptor
- Endocrine Disruptor Effects
- Disruptor Effects, Endocrine
- Effects, Endocrine Disruptor
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Below are MeSH descriptors whose meaning is more general than "Endocrine Disruptors".
Below are MeSH descriptors whose meaning is more specific than "Endocrine Disruptors".
This graph shows the total number of publications written about "Endocrine Disruptors" by people in UAMS Profiles by year, and whether "Endocrine Disruptors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 | | 2020 | 2 | 0 | 2 | | 2018 | 2 | 0 | 2 | | 2016 | 5 | 1 | 6 | | 2015 | 3 | 0 | 3 | | 2014 | 2 | 0 | 2 | | 2011 | 1 | 1 | 2 | | 2010 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Endocrine Disruptors" by people in Profiles over the past ten years.
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Cortes-Ramirez SA, Ho SM, Leung YK. Endocrine-Disrupting Chemicals: A Looming Threat to Current and Future Generations. Int J Mol Sci. 2024 Jul 27; 25(15).
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Leung YK. A Silent Threat: Exploring the Impact of Endocrine Disruption on Human Health. Int J Mol Sci. 2023 Jun 06; 24(12).
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Merii MH, Fardoun MM, El Asmar K, Khalil MI, Eid AH, Dhaini HR. Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain. Neurotoxicol Teratol. 2022 Jul-Aug; 92:107095.
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Ho SM, Rao R, Ouyang B, Tam NNC, Schoch E, Song D, Ying J, Leung YK, Govindarajah V, Tarapore P. Three-Generation Study of Male Rats Gestationally Exposed to High Butterfat and Bisphenol A: Impaired Spermatogenesis, Penetrance with Reduced Severity. Nutrients. 2021 Oct 17; 13(10).
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Heindel JJ, Belcher S, Flaws JA, Prins GS, Ho SM, Mao J, Patisaul HB, Ricke W, Rosenfeld CS, Soto AM, Vom Saal FS, Zoeller RT. Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies. Reprod Toxicol. 2020 12; 98:29-60.
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Williams AE, Watt J, Robertson LW, Gadupudi G, Osborn ML, Soares MJ, Iqbal K, Pedersen KB, Shankar K, Littleton S, Maimone C, Eti NA, Suva LJ, Ronis MJJ. Skeletal Toxicity of Coplanar Polychlorinated Biphenyl Congener 126 in the Rat Is Aryl Hydrocarbon Receptor Dependent. Toxicol Sci. 2020 05 01; 175(1):113-125.
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Cheong A, Johnson SA, Howald EC, Ellersieck MR, Camacho L, Lewis SM, Vanlandingham MM, Ying J, Ho SM, Rosenfeld CS. Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study. Epigenetics. 2018; 13(7):704-720.
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He P, Matich EK, Yonkos LT, Friedman AE, Atilla-Gokcumen GE, Aga DS. Mass spectrometry based detection of common vitellogenin peptides across fish species for assessing exposure to estrogenic compounds in aquatic environments. Sci Total Environ. 2019 Jan 01; 646:400-408.
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Ho SM, Rao R, To S, Schoch E, Tarapore P. Bisphenol A and its analogues disrupt centrosome cycle and microtubule dynamics in prostate cancer. Endocr Relat Cancer. 2017 02; 24(2):83-96.
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Slavov SH, Beger RD. Rigorous 3-dimensional spectral data activity relationship approach modeling strategy for ToxCast estrogen receptor data classification, validation, and feature extraction. Environ Toxicol Chem. 2017 03; 36(3):823-830.
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Ehrlich S, Lambers D, Baccarelli A, Khoury J, Macaluso M, Ho SM. Endocrine Disruptors: A Potential Risk Factor for Gestational Diabetes Mellitus. Am J Perinatol. 2016 11; 33(13):1313-1318.
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Ho SM, Cheong A, Adgent MA, Veevers J, Suen AA, Tam NNC, Leung YK, Jefferson WN, Williams CJ. Environmental factors, epigenetics, and developmental origin of reproductive disorders. Reprod Toxicol. 2017 03; 68:85-104.
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Wang Q, Trevino LS, Wong RL, Medvedovic M, Chen J, Ho SM, Shen J, Foulds CE, Coarfa C, O'Malley BW, Shilatifard A, Walker CL. Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk. Mol Endocrinol. 2016 Aug; 30(8):856-71.
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Mansouri K, Abdelaziz A, Rybacka A, Roncaglioni A, Tropsha A, Varnek A, Zakharov A, Worth A, Richard AM, Grulke CM, Trisciuzzi D, Fourches D, Horvath D, Benfenati E, Muratov E, Wedebye EB, Grisoni F, Mangiatordi GF, Incisivo GM, Hong H, Ng HW, Tetko IV, Balabin I, Kancherla J, Shen J, Burton J, Nicklaus M, Cassotti M, Nikolov NG, Nicolotti O, Andersson PL, Zang Q, Politi R, Beger RD, Todeschini R, Huang R, Farag S, Rosenberg SA, Slavov S, Hu X, Judson RS. CERAPP: Collaborative Estrogen Receptor Activity Prediction Project. Environ Health Perspect. 2016 07; 124(7):1023-33.
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Stevenson M, Alexander B, Baxter CS, Leung YK. Evaluating Endocrine Disruption Activity of Deposits on Firefighting Gear Using a Sensitive and High Throughput Screening Method. J Occup Environ Med. 2015 Dec; 57(12):e153-7.
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Lam HM, Ho SM, Chen J, Medvedovic M, Tam NN. Bisphenol A Disrupts HNF4a-Regulated Gene Networks Linking to Prostate Preneoplasia and Immune Disruption in Noble Rats. Endocrinology. 2016 Jan; 157(1):207-19.
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Seachrist DD, Bonk KW, Ho SM, Prins GS, Soto AM, Keri RA. A review of the carcinogenic potential of bisphenol A. Reprod Toxicol. 2016 Jan; 59:167-82.
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