 Fibroblast Growth Factor 2
"Fibroblast Growth Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).
| Descriptor ID |
D016222
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| MeSH Number(s) |
D12.644.276.624.120 D12.776.467.624.120 D23.529.624.120
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| Concept/Terms |
Fibroblast Growth Factor 2- Fibroblast Growth Factor 2
- Cartilage-Derived Growth Factor
- Cartilage Derived Growth Factor
- Class II Heparin-Binding Growth Factor
- FGF-2
- FGF 2
- Prostatropin
- Fibroblast Growth Factor, Basic
- Fibroblast Growth Factor-2
- HBGF-2
- Heparin-Binding Growth Factor Class II
- Prostate Epithelial Cell Growth Factor
- Basic Fibroblast Growth Factor
- FGF2
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Below are MeSH descriptors whose meaning is more general than "Fibroblast Growth Factor 2".
Below are MeSH descriptors whose meaning is more specific than "Fibroblast Growth Factor 2".
This graph shows the total number of publications written about "Fibroblast Growth Factor 2" by people in UAMS Profiles by year, and whether "Fibroblast Growth Factor 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 | | 2015 | 2 | 1 | 3 | | 2013 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2010 | 1 | 0 | 1 | | 2005 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2002 | 1 | 1 | 2 | | 2001 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 1999 | 1 | 1 | 2 | | 1996 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fibroblast Growth Factor 2" by people in Profiles over the past ten years.
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Makhoul I, Todorova VK, Siegel ER, Erickson SW, Dhakal I, Raj VR, Lee JY, Orloff MS, Griffin RJ, Henry-Tillman RS, Klimberg S, Hutchins LF, Kadlubar SA. Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients. PLoS One. 2017; 12(1):e0168550.
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D'Mello S, Atluri K, Geary SM, Hong L, Elangovan S, Salem AK. Bone Regeneration Using Gene-Activated Matrices. AAPS J. 2017 01; 19(1):43-53.
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Makhoul I, Griffin RJ, Siegel E, Lee J, Dhakal I, Raj V, Jamshidi-Parsian A, Klimberg S, Hutchins LF, Kadlubar S. High-circulating Tie2 Is Associated With Pathologic Complete Response to Chemotherapy and Antiangiogenic Therapy in Breast Cancer. Am J Clin Oncol. 2016 06; 39(3):248-54.
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Erdem H, Gundogdu B, Ankarali H, Yasar M, Sener E, Oktay M, Bahadir A, Uzunlar AK, Gursan N, Ozaydin I, Sahiner C. Correlation of astrocyte elevated gene-1, basic-fibroblast growth factor, beta-catenin, Ki-67, tumor necrosis factor-alfa with prognostic parameters in ductal carcinomas and ductal intraepithelial neoplasms. Niger J Clin Pract. 2015 Sep-Oct; 18(5):638-43.
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Atluri K, Seabold D, Hong L, Elangovan S, Salem AK. Nanoplex-Mediated Codelivery of Fibroblast Growth Factor and Bone Morphogenetic Protein Genes Promotes Osteogenesis in Human Adipocyte-Derived Mesenchymal Stem Cells. Mol Pharm. 2015 Aug 03; 12(8):3032-42.
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Dow AL, Lin TV, Chartoff EH, Potter D, McPhie DL, Van't Veer AV, Knoll AT, Lee KN, Neve RL, Patel TB, Ongur D, Cohen BM, Carlezon WA. Sprouty2 in the dorsal hippocampus regulates neurogenesis and stress responsiveness in rats. PLoS One. 2015; 10(3):e0120693.
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