 Wiskott-Aldrich Syndrome Protein Family
"Wiskott-Aldrich Syndrome Protein Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
| Descriptor ID |
D051300
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| MeSH Number(s) |
D05.750.078.730.912 D12.776.220.525.912
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Wiskott-Aldrich Syndrome Protein Family".
Below are MeSH descriptors whose meaning is more specific than "Wiskott-Aldrich Syndrome Protein Family".
This graph shows the total number of publications written about "Wiskott-Aldrich Syndrome Protein Family" by people in UAMS Profiles by year, and whether "Wiskott-Aldrich Syndrome Protein Family" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Wiskott-Aldrich Syndrome Protein Family" by people in Profiles over the past ten years.
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Shao L, Chang J, Feng W, Wang X, Williamson EA, Li Y, Schajnovitz A, Scadden D, Mortensen LJ, Lin CP, Li L, Paulson A, Downing J, Zhou D, Hromas RA. The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow. Nat Commun. 2018 06 18; 9(1):2377.
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