 GATA4 Transcription Factor
"GATA4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GATA transcription factor that is expressed in the MYOCARDIUM of developing heart and has been implicated in the differentiation of CARDIAC MYOCYTES. GATA4 is activated by PHOSPHORYLATION and regulates transcription of cardiac-specific genes.
| Descriptor ID |
D050991
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| MeSH Number(s) |
D12.776.260.257.400 D12.776.930.321.400
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| Concept/Terms |
GATA4 Transcription Factor- GATA4 Transcription Factor
- Transcription Factor, GATA4
- Transcription Factor GATA-4
- Factor GATA-4, Transcription
- GATA-4, Transcription Factor
- Transcription Factor GATA 4
- Transcription Factor GATA4
- Factor GATA4, Transcription
- GATA4, Transcription Factor
- GATA-4 Transcription Factor
- GATA 4 Transcription Factor
- Transcription Factor, GATA-4
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Below are MeSH descriptors whose meaning is more general than "GATA4 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GATA4 Transcription Factor".
This graph shows the total number of publications written about "GATA4 Transcription Factor" by people in UAMS Profiles by year, and whether "GATA4 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "GATA4 Transcription Factor" by people in Profiles over the past ten years.
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de Andr?s MP, Jackson RJ, Felipe I, Zagorac S, Pilarsky C, Schlitter AM, Martinez de Villareal J, Jang GH, Costello E, Gallinger S, Ghaneh P, Greenhalf W, Kn?sel T, Palmer DH, Ruemmele P, Weichert W, Buechler M, Hackert T, Neoptolemos JP, Notta F, Malats N, Martinelli P, Real FX. GATA4 and GATA6 loss-of-expression is associated with extinction of the classical programme and poor outcome in pancreatic ductal adenocarcinoma. Gut. 2023 03; 72(3):535-548.
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Riching AS, Danis E, Zhao Y, Cao Y, Chi C, Bagchi RA, Klein BJ, Xu H, Kutateladze TG, McKinsey TA, Buttrick PM, Song K. Suppression of canonical TGF-? signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis. J Mol Cell Cardiol. 2021 04; 153:44-59.
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Musfee FI, Guo D, Pinard AC, Hostetler EM, Blue EE, Nickerson DA, Bamshad MJ, Milewicz DM, Prakash SK. Rare deleterious variants of NOTCH1, GATA4, SMAD6, and ROBO4 are enriched in BAV with early onset complications but not in BAV with heritable thoracic aortic disease. Mol Genet Genomic Med. 2020 10; 8(10):e1406.
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Mauro KL, Helton SG, Rosoff DB, Luo A, Schwandt M, Jung J, Lee J, Muench C, Lohoff FW. Association Analysis Between Genetic Variation in GATA Binding Protein 4 (GATA4) and Alcohol Use Disorder. Alcohol Alcohol. 2018 Jul 01; 53(4):361-367.
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Kim HN, Chang J, Shao L, Han L, Iyer S, Manolagas SC, O'Brien CA, Jilka RL, Zhou D, Almeida M. DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age. Aging Cell. 2017 08; 16(4):693-703.
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