Ribonucleoprotein, U1 Small Nuclear
"Ribonucleoprotein, U1 Small Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.
Descriptor ID |
D017412
|
MeSH Number(s) |
D12.776.157.725.500.875.600 D12.776.664.962.500.875.600
|
Concept/Terms |
Ribonucleoprotein, U1 Small Nuclear- Ribonucleoprotein, U1 Small Nuclear
- U1 Small Nuclear Ribonucleoproteins
- Ribonucleoproteins, Small, U1
- Small Nuclear Ribonucleoproteins, U1
- U1 snRNP
|
Below are MeSH descriptors whose meaning is more general than "Ribonucleoprotein, U1 Small Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Ribonucleoprotein, U1 Small Nuclear".
This graph shows the total number of publications written about "Ribonucleoprotein, U1 Small Nuclear" by people in UAMS Profiles by year, and whether "Ribonucleoprotein, U1 Small Nuclear" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
---|
2022 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Ribonucleoprotein, U1 Small Nuclear" by people in Profiles over the past ten years.
-
Chen PC, Han X, Shaw TI, Fu Y, Sun H, Niu M, Wang Z, Jiao Y, Teubner BJW, Eddins D, Beloate LN, Bai B, Mertz J, Li Y, Cho JH, Wang X, Wu Z, Liu D, Poudel S, Yuan ZF, Mancieri A, Low J, Lee HM, Patton MH, Earls LR, Stewart E, Vogel P, Hui Y, Wan S, Bennett DA, Serrano GE, Beach TG, Dyer MA, Smeyne RJ, Moldoveanu T, Chen T, Wu G, Zakharenko SS, Yu G, Peng J. Alzheimer's disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment. Nat Aging. 2022 10; 2(10):923-940.
|
People People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|