 Procollagen-Proline Dioxygenase
"Procollagen-Proline Dioxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl-containing-peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES.
| Descriptor ID |
D011393
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| MeSH Number(s) |
D08.811.682.690.708.673
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| Concept/Terms |
Procollagen-Proline Dioxygenase- Procollagen-Proline Dioxygenase
- Dioxygenase, Procollagen-Proline
- Procollagen Proline Dioxygenase
- Procollagen Prolyl 4-Hydroxylase
- 4-Hydroxylase, Procollagen Prolyl
- Procollagen Prolyl 4 Hydroxylase
- Prolyl 4-Hydroxylase, Procollagen
- Protocollagen Prolyl Hydroxylase
- Hydroxylase, Protocollagen Prolyl
- Prolyl Hydroxylase, Protocollagen
- Proline,2-Oxoglutarate 4-Dioxygenase
- 4-Dioxygenase, Proline,2-Oxoglutarate
- Proline,2 Oxoglutarate 4 Dioxygenase
- Prolyl 4-Hydroxylase
- 4-Hydroxylase, Prolyl
- Prolyl 4 Hydroxylase
- Prolyl Hydroxylase
- Hydroxylase, Prolyl
- Peptidyl Prolyl Hydroxylase
- Hydroxylase, Peptidyl Prolyl
- Prolyl Hydroxylase, Peptidyl
- Proline Hydroxylase
- Hydroxylase, Proline
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Below are MeSH descriptors whose meaning is more general than "Procollagen-Proline Dioxygenase".
Below are MeSH descriptors whose meaning is more specific than "Procollagen-Proline Dioxygenase".
This graph shows the total number of publications written about "Procollagen-Proline Dioxygenase" by people in UAMS Profiles by year, and whether "Procollagen-Proline Dioxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Procollagen-Proline Dioxygenase" by people in Profiles over the past ten years.
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Hudson DM, Weis M, Rai J, Joeng KS, Dimori M, Lee BH, Morello R, Eyre DR. P3h3-null and Sc65-null Mice Phenocopy the Collagen Lysine Under-hydroxylation and Cross-linking Abnormality of Ehlers-Danlos Syndrome Type VIA. J Biol Chem. 2017 03 03; 292(9):3877-3887.
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