 Norepinephrine
"Norepinephrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
| Descriptor ID |
D009638
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| MeSH Number(s) |
D02.033.100.291.502 D02.092.063.480 D02.092.211.215.311.560 D02.092.311.461.484
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| Concept/Terms |
Norepinephrine- Norepinephrine
- Noradrenaline
- Levarterenol
- Levonorepinephrine
Levophed- Levophed
- Levophed Bitartrate
- Bitartrate, Levophed
- Abbott Brand of Levophed Bitartrate
Noradrénaline tartrate renaudin- Noradrénaline tartrate renaudin
- renaudin, Noradrénaline tartrate
- tartrate renaudin, Noradrénaline
- Renaudin Brand of Norepinephrine Bitartrate
Norepinephrine Bitartrate- Norepinephrine Bitartrate
- Bitartrate, Norepinephrine
- Norepinephrine l-Tartrate (1:1)
- Noradrenaline Bitartrate
- Bitartrate, Noradrenaline
Arterenol- Arterenol
- Aventis Brand of Norepinephrine Hydrochloride
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Below are MeSH descriptors whose meaning is more general than "Norepinephrine".
Below are MeSH descriptors whose meaning is more specific than "Norepinephrine".
This graph shows the total number of publications written about "Norepinephrine" by people in UAMS Profiles by year, and whether "Norepinephrine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 1 | 1 | | 2022 | 0 | 2 | 2 | | 2021 | 1 | 0 | 1 | | 2020 | 2 | 1 | 3 | | 2019 | 2 | 1 | 3 | | 2018 | 1 | 2 | 3 | | 2017 | 2 | 0 | 2 | | 2016 | 2 | 0 | 2 | | 2015 | 0 | 4 | 4 | | 2014 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2010 | 0 | 3 | 3 | | 2009 | 2 | 0 | 2 | | 2008 | 0 | 2 | 2 | | 2007 | 1 | 1 | 2 | | 2006 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 | | 2004 | 1 | 2 | 3 | | 2002 | 3 | 3 | 6 | | 2001 | 0 | 2 | 2 | | 2000 | 3 | 3 | 6 | | 1999 | 0 | 3 | 3 | | 1998 | 0 | 3 | 3 | | 1996 | 1 | 3 | 4 | | 1995 | 0 | 1 | 1 | | 1994 | 2 | 3 | 5 | | 1993 | 0 | 1 | 1 | | 1991 | 1 | 0 | 1 | | 1989 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Norepinephrine" by people in Profiles over the past ten years.
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Yerke JR, Mireles-Cabodevila E, Chen AY, Bass SN, Reddy AJ, Bauer SR, Kokoczka L, Dugar S, Moghekar A. Peripheral Administration of Norepinephrine: A Prospective Observational Study. Chest. 2024 Feb; 165(2):348-355.
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Levy RA, Reiter PD, Spear M, Santana A, Silveira L, Cox S, Mourani PM, Maddux AB. Peripheral Vasoactive Administration in Critically Ill Children With Shock: A Single-Center Retrospective Cohort Study. Pediatr Crit Care Med. 2022 08 01; 23(8):618-625.
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T?rck P, Nemec-Bakk A, Talwar T, Suntres Z, Bell?-Klein A, da Rosa Araujo AS, Khaper N. Blueberry extract attenuates norepinephrine-induced oxidative stress and apoptosis in H9c2 cardiac cells. Mol Cell Biochem. 2022 Mar; 477(3):663-672.
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Tang WC, Chang YW, Che M, Wang MH, Lai KK, Fueger PT, Huang W, Lin SB, Lai KKY. Thioacetamide-Induced Norepinephrine Production by Hepatocytes is Associated with Hepatic Stellate Cell Activation and Liver Fibrosis. Curr Mol Pharmacol. 2022; 15(2):454-461.
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Maier J, Rauter L, Rudin D, Niello M, Holy M, Schmid D, Wilson J, Blough BE, Gannon BM, Murnane KS, Sitte HH. a-PPP and its derivatives are selective partial releasers at the human norepinephrine transporter: A pharmacological characterization of interactions between pyrrolidinopropiophenones and high and low affinity monoamine transporters. Neuropharmacology. 2021 06 01; 190:108570.
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Hawn JM, Bauer SR, Yerke J, Li M, Wang X, Reddy AJ, Mireles-Cabodevila E, Sacha GL. Effect of Phenylephrine Push Before Continuous Infusion Norepinephrine in Patients With Septic Shock. Chest. 2021 05; 159(5):1875-1883.
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Moore CL, Henry DS, McClenahan SJ, Ball KK, Rusch NJ, Rhee SW. Metoprolol Impairs ?1-Adrenergic Receptor-Mediated Vasodilation in Rat Cerebral Arteries: Implications for ?-Blocker Therapy. J Pharmacol Exp Ther. 2021 01; 376(1):127-135.
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Der-Nigoghossian C, Hammond DA, Ammar MA. Narrative Review of Controversies Involving Vasopressin Use in Septic Shock and Practical Considerations. Ann Pharmacother. 2020 07; 54(7):706-714.
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de Lima-Seolin BG, Nemec-Bakk A, Forsyth H, Kirk S, da Rosa Araujo AS, Schenkel PC, Bell?-Klein A, Khaper N. Bucindolol Modulates Cardiac Remodeling by Attenuating Oxidative Stress in H9c2 Cardiac Cells Exposed to Norepinephrine. Oxid Med Cell Longev. 2019; 2019:6325424.
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Vilke GM, Mash DC, Pardo M, Bozeman W, Hall C, Sloane C, Wilson MP, Coyne CJ, Xie X, Castillo EM. EXCITATION study: Unexplained in-custody deaths: Evaluating biomarkers of stress and agitation. J Forensic Leg Med. 2019 Aug; 66:100-106.
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Hammond DA, Sacha GL, Bissell BD, Musallam N, Altshuler D, Flannery AH, Lam SW, Bauer SR. Effects of Norepinephrine and Vasopressin Discontinuation Order in the Recovery Phase of Septic Shock: A Systematic Review and Individual Patient Data Meta-Analysis. Pharmacotherapy. 2019 05; 39(5):544-552.
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Menich BE, Miano TA, Patel GP, Hammond DA. Norepinephrine and Vasopressin Compared With Norepinephrine and Epinephrine in Adults With Septic Shock. Ann Pharmacother. 2019 09; 53(9):877-885.
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Allman BR, Morrissey MC, Kim JS, Panton LB, Contreras RJ, Hickner RC, Ormsbee MJ. Fat metabolism and acute resistance exercise in trained women. J Appl Physiol (1985). 2019 03 01; 126(3):739-745.
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Musayeva A, Manicam C, Steege A, Brochhausen C, Straub BK, Bell K, Pfeiffer N, Gericke A. Role of a1-adrenoceptor subtypes on corneal epithelial thickness and cell proliferation in mice. Am J Physiol Cell Physiol. 2018 11 01; 315(5):C757-C765.
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Baladi MG, Forster MJ, Gatch MB, Mailman RB, Hyman DL, Carter LP, Janowsky A. Characterization of the Neurochemical and Behavioral Effects of Solriamfetol (JZP-110), a Selective Dopamine and Norepinephrine Reuptake Inhibitor. J Pharmacol Exp Ther. 2018 08; 366(2):367-376.
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Annane D, Ouanes-Besbes L, de Backer D, DU B, Gordon AC, Hern?ndez G, Olsen KM, Osborn TM, Peake S, Russell JA, Cavazzoni SZ. A global perspective on vasoactive agents in shock. Intensive Care Med. 2018 06; 44(6):833-846.
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Hammond DA, Ficek OA, Painter JT, McCain K, Cullen J, Brotherton AL, Kakkera K, Chopra D, Meena N. Prospective Open-label Trial of Early Concomitant Vasopressin and Norepinephrine Therapy versus Initial Norepinephrine Monotherapy in Septic Shock. Pharmacotherapy. 2018 05; 38(5):531-538.
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Hammond DA, Cullen J, Painter JT, McCain K, Clem OA, Brotherton AL, Chopra D, Meena N. Efficacy and Safety of the Early Addition of Vasopressin to Norepinephrine in Septic Shock. J Intensive Care Med. 2019 Nov-Dec; 34(11-12):910-916.
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Hammond DA, McCain K, Painter JT, Clem OA, Cullen J, Brotherton AL, Chopra D, Meena N. Discontinuation of Vasopressin Before Norepinephrine in the Recovery Phase of Septic Shock. J Intensive Care Med. 2019 Oct; 34(10):805-810.
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Dienel GA, Cruz NF. Aerobic glycolysis during brain activation: adrenergic regulation and influence of norepinephrine on astrocytic metabolism. J Neurochem. 2016 07; 138(1):14-52.
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Phillips C, Fahimi A, Das D, Mojabi FS, Ponnusamy R, Salehi A. Noradrenergic System in Down Syndrome and Alzheimer's Disease A Target for Therapy. Curr Alzheimer Res. 2016; 13(1):68-83.
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Velez JC, Kadian M, Taburyanskaya M, Bohm NM, Delay TA, Karakala N, Rockey DC, Nietert PJ, Goodwin AJ, Whelan TP. Hepatorenal Acute Kidney Injury and the Importance of Raising Mean Arterial Pressure. Nephron. 2015; 131(3):191-201.
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Xie H, Li C, He Y, Griffin R, Ye Q, Li L. Chronic stress promotes oral cancer growth and angiogenesis with increased circulating catecholamine and glucocorticoid levels in a mouse model. Oral Oncol. 2015 Nov; 51(11):991-997.
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Moore CL, McClenahan SJ, Hanvey HM, Jang DS, Nelson PL, Joseph BK, Rhee SW. Beta1-adrenergic receptor-mediated dilation of rat cerebral artery requires Shaker-type KV1 channels on PSD95 scaffold. J Cereb Blood Flow Metab. 2015 Sep; 35(9):1537-46.
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Armaiz-Pena GN, Gonzalez-Villasana V, Nagaraja AS, Rodriguez-Aguayo C, Sadaoui NC, Stone RL, Matsuo K, Dalton HJ, Previs RA, Jennings NB, Dorniak P, Hansen JM, Arevalo JM, Cole SW, Lutgendorf SK, Sood AK, Lopez-Berestein G. Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth. Oncotarget. 2015 Feb 28; 6(6):4266-73.
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