 Transforming Growth Factor beta2
"Transforming Growth Factor beta2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
| Descriptor ID |
D053781
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| MeSH Number(s) |
D12.644.276.374.687.200 D12.644.276.954.800.720.200 D12.644.276.963.720.200 D12.776.467.374.687.200 D12.776.467.942.800.720.200 D12.776.467.960.720.200 D23.529.374.687.200 D23.529.942.800.720.200 D23.529.960.720.200
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| Concept/Terms |
Transforming Growth Factor beta2- Transforming Growth Factor beta2
- Glioblastoma-Derived T-Cell Suppressor Factor
- Glioblastoma Derived T Cell Suppressor Factor
- Suppressor Factor, T-Cell, Glioblastoma-Derived
- TGF-beta2
- TGF-beta-2
- Cartilage-Inducing Factor-B
- Cartilage Inducing Factor B
- BSC-1 Cell Growth Inhibitor
- BSC 1 Cell Growth Inhibitor
- Polyergin
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta2".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta2".
This graph shows the total number of publications written about "Transforming Growth Factor beta2" by people in UAMS Profiles by year, and whether "Transforming Growth Factor beta2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transforming Growth Factor beta2" by people in Profiles over the past ten years.
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Mondal C, Gacha-Garay MJ, Larkin KA, Adikes RC, Di Martino JS, Chien CC, Fraser M, Eni-Aganga I, Agullo-Pascual E, Cialowicz K, Ozbek U, Naba A, Gaitas A, Fu TM, Upadhyayula S, Betzig E, Matus DQ, Martin BL, Bravo-Cordero JJ. A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-?2 signaling. Cell Rep. 2022 09 20; 40(12):111358.
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Matta B, Bora PS, Neuhouser AJ, Bora NS. Inhibitory role of transforming growth factor ?2 in experimental autoimmune anterior uveitis. Graefes Arch Clin Exp Ophthalmol. 2019 May; 257(5):953-960.
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