 Erythromycin
"Erythromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
| Descriptor ID |
D004917
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| MeSH Number(s) |
D02.540.505.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Erythromycin".
Below are MeSH descriptors whose meaning is more specific than "Erythromycin".
This graph shows the total number of publications written about "Erythromycin" by people in UAMS Profiles by year, and whether "Erythromycin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "Erythromycin" by people in Profiles over the past ten years.
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Erol E, Locke S, Saied A, Cruz Penn MJ, Smith J, Fortner J, Carter C. Antimicrobial susceptibility patterns of Rhodococcus equi from necropsied foals with rhodococcosis. Vet Microbiol. 2020 Mar; 242:108568.
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Sanson MA, Macias OR, Shah BJ, Hanson B, Vega LA, Alamarat Z, Flores AR. Unexpected relationships between frequency of antimicrobial resistance, disease phenotype and emm type in group A Streptococcus. Microb Genom. 2019 11; 5(11).
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Huber L, Gigu?re S, Slovis NM, Carter CN, Barr BS, Cohen ND, Elam J, Erol E, Locke SJ, Phillips ED, Smith JL. Emergence of Resistance to Macrolides and Rifampin in Clinical Isolates of Rhodococcus equi from Foals in Central Kentucky, 1995 to 2017. Antimicrob Agents Chemother. 2019 01; 63(1).
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Takagi M, Sakamoto M, Itoh T, Fujiwara R. Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. Drug Metab Pharmacokinet. 2015 Aug; 30(4):288-94.
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