Multiple Organ Failure
"Multiple Organ Failure" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
Descriptor ID |
D009102
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MeSH Number(s) |
C23.550.835.525
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Concept/Terms |
Multiple Organ Failure- Multiple Organ Failure
- Multiple Organ Dysfunction Syndrome
- Organ Failure, Multiple
- Failure, Multiple Organ
- Multiple Organ Failures
- MODS
- Organ Dysfunction Syndrome, Multiple
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Below are MeSH descriptors whose meaning is more general than "Multiple Organ Failure".
Below are MeSH descriptors whose meaning is more specific than "Multiple Organ Failure".
This graph shows the total number of publications written about "Multiple Organ Failure" by people in UAMS Profiles by year, and whether "Multiple Organ Failure" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2024 | 0 | 1 | 1 | 2023 | 2 | 2 | 4 | 2021 | 2 | 1 | 3 | 2020 | 1 | 0 | 1 | 2019 | 1 | 2 | 3 | 2018 | 1 | 0 | 1 | 2017 | 1 | 0 | 1 | 2016 | 0 | 2 | 2 | 2015 | 0 | 2 | 2 | 2014 | 1 | 0 | 1 | 2013 | 0 | 1 | 1 | 2012 | 1 | 0 | 1 | 2011 | 0 | 1 | 1 | 2010 | 1 | 1 | 2 | 2008 | 0 | 1 | 1 | 2006 | 2 | 0 | 2 | 2003 | 1 | 1 | 2 | 2002 | 1 | 1 | 2 |
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Below are the most recent publications written about "Multiple Organ Failure" by people in Profiles over the past ten years.
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Yehya N, Booth TJ, Ardhanari GD, Thompson JM, Lam LKM, Till JE, Mai MV, Keim G, McKeone DJ, Halstead ES, Lahni P, Varisco BM, Zhou W, Carpenter EL, Christie JD, Mangalmurti NS. Inflammatory and tissue injury marker dynamics in pediatric acute respiratory distress syndrome. J Clin Invest. 2024 Apr 04; 134(10).
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Atreya MR, Banerjee S, Lautz AJ, Alder MN, Varisco BM, Wong HR, Muszynski JA, Hall MW, Sanchez-Pinto LN, Kamaleswaran R. Machine learning-driven identification of the gene-expression signature associated with a persistent multiple organ dysfunction trajectory in critical illness. EBioMedicine. 2024 Jan; 99:104938.
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VanBuren JM, Hall M, Zuppa AF, Mourani PM, Carcillo J, Dean JM, Watt K, Holubkov R. The Design of Nested Adaptive Clinical Trials of Multiple Organ Dysfunction Syndrome Children in a Single Study. Pediatr Crit Care Med. 2023 Dec 01; 24(12):e635-e646.
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Novak T, Crawford JC, Hahn G, Hall MW, Thair SA, Newhams MM, Chou J, Mourani PM, Tarquinio KM, Markovitz B, Loftis LL, Weiss SL, Higgerson R, Schwarz AJ, Pinto NP, Thomas NJ, Gedeit RG, Sanders RC, Mahapatra S, Coates BM, Cvijanovich NZ, Ackerman KG, Tellez DW, McQuillen P, Kurachek SC, Shein SL, Lange C, Thomas PG, Randolph AG. Transcriptomic profiles of multiple organ dysfunction syndrome phenotypes in pediatric critical influenza. Front Immunol. 2023; 14:1220028.
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Johnson DB, Atkins MB, Hennessy C, Wise-Draper T, Heilman H, Awosika J, Bakouny Z, Labaki C, Saliby RM, Hwang C, Singh SRK, Balanchivadze N, Friese CR, Fecher LA, Yoon JJ, Hayes-Lattin B, Bilen MA, Castellano CA, Lyman GH, Tachiki L, Shah SA, Glover MJ, Flora DB, Wulff-Burchfield E, Kasi A, Abbasi SH, Farmakiotis D, Viera K, Klein EJ, Weissman LB, Jani C, Puc M, Fahey CC, Reuben DY, Mishra S, Beeghly-Fadiel A, French B, Warner JL. Impact of COVID-19 in patients on active melanoma therapy and with history of melanoma. BMC Cancer. 2023 Mar 23; 23(1):265.
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Wong AI, Charpignon M, Kim H, Josef C, de Hond AAH, Fojas JJ, Tabaie A, Liu X, Mireles-Cabodevila E, Carvalho L, Kamaleswaran R, Madushani RWMA, Adhikari L, Holder AL, Steyerberg EW, Buchman TG, Lough ME, Celi LA. Analysis of Discrepancies Between Pulse Oximetry and Arterial Oxygen Saturation Measurements by Race and Ethnicity and Association With Organ Dysfunction and Mortality. JAMA Netw Open. 2021 11 01; 4(11):e2131674.
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Mitma AA, Burgess MJ, van Rhee F. Ehrlichia-induced hemophagocytic lymphohistiocytosis after autologous stem cell transplant. Transpl Infect Dis. 2021 Aug; 23(4):e13621.
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Richards JE, Fedeles BT, Chow JH, Morrison JJ, Renner C, Trinh AT, Schlee CS, Koerner K, Grissom TE, Betzold RD, Scalea TM, Kozar RA. Is Tranexamic Acid Associated With Mortality or Multiple Organ Failure Following Severe Injury? Shock. 2021 01 01; 55(1):55-60.
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Matehuala S, Pasala S, Goudie A, Fiser R, Weiss S, Irby K, Crary S, Wang A, Sanders R. Association Between Elevated RBC Distribution Width and Multiple Organ Dysfunction in Pediatric Critical Illness. Pediatr Crit Care Med. 2020 09; 21(9):e740-e746.
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Ince C, De Backer D, Mayeux PR. Microvascular Dysfunction in the Critically Ill. Crit Care Clin. 2020 Apr; 36(2):323-331.
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Roberts AL, Sammons JS, Mourani PM, Thomas NJ, Yehya N. Specific Viral Etiologies Are Associated With Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2019 09; 20(9):e441-e446.
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Kok B, Duarte-Rojo A, Tandon P. Predicting Functional Status After Transplantation in Patients With Acute-on-Chronic Liver Failure. Clin Gastroenterol Hepatol. 2020 01; 18(1):54-56.
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Smeets XJNM, Knoester I, Grooteman KV, Singh VK, Banks PA, Papachristou GI, Duarte-Rojo A, Robles-Diaz G, Kievit W, Besselink MGH, Verdonk RC, Van Santvoort HC, Drenth JPH, Belias M, Van Geenen EJM. The association between obesity and outcomes in acute pancreatitis: an individual patient data meta-analysis. Eur J Gastroenterol Hepatol. 2019 03; 31(3):316-322.
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Claushuis TAM, de Stoppelaar SF, de Vos AF, Grootemaat AE, van der Wel NN, Roelofs JJTH, Ware J, Van't Veer C, van der Poll T. Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis. Arterioscler Thromb Vasc Biol. 2018 08; 38(8):1772-1784.
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Finnerty CC, Capek KD, Voigt C, Hundeshagen G, Cambiaso-Daniel J, Porter C, Sousse LE, El Ayadi A, Zapata-Sirvent R, Guillory AN, Suman OE, Herndon DN. The P50 Research Center in Perioperative Sciences: How the investment by the National Institute of General Medical Sciences in team science has reduced postburn mortality. J Trauma Acute Care Surg. 2017 09; 83(3):532-542.
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Habetz K, Ramakrishnaiah R, Raina SK, Fitzgerald RT, Hinduja A. Posterior Reversible Encephalopathy Syndrome: A Comparative Study of Pediatric Versus Adult Patients. Pediatr Neurol. 2016 12; 65:45-51.
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Smith JA, Mayeux PR, Schnellmann RG. Delayed Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Inhibition by Trametinib Attenuates Systemic Inflammatory Responses and Multiple Organ Injury in Murine Sepsis. Crit Care Med. 2016 08; 44(8):e711-20.
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Guidry-Grimes L. The Case of Ms D: A Family's Request for Posthumous Procurement of Ovaries. J Clin Ethics. 2016; 27(1):51-8.
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Stroud MH, Sanders RC, Moss MM, Sullivan JE, Prodhan P, Melguizo-Castro M, Nick T. Goal-Directed Resuscitative Interventions During Pediatric Interfacility Transport. Crit Care Med. 2015 Aug; 43(8):1692-8.
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Klair JS, Abraham RR, Jones J, Girotra M. A 'shock-ing' endoscopic finding on esophagogastroduodenoscopy. BMJ Case Rep. 2015 Feb 09; 2015.
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