 Interleukin-1alpha
"Interleukin-1alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.
| Descriptor ID |
D053582
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| MeSH Number(s) |
D12.644.276.374.465.501.300 D12.644.276.374.500.400.300 D12.776.467.374.465.501.300 D12.776.467.374.500.400.300 D23.529.374.465.501.300 D23.529.374.500.400.300
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| Concept/Terms |
Interleukin-1alpha- Interleukin-1alpha
- Interleukin 1alpha
- Interleukin-1 alpha
- Interleukin 1 alpha
- Hematopoietin-1
- Hematopoietin 1
- IL-1 alpha
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Below are MeSH descriptors whose meaning is more general than "Interleukin-1alpha".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1alpha".
This graph shows the total number of publications written about "Interleukin-1alpha" by people in UAMS Profiles by year, and whether "Interleukin-1alpha" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2012 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-1alpha" by people in Profiles over the past ten years.
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Nagarajan UM, Cho C, Gyorke CE, Nagarajan S, Ezzell JA, Brochu H, Huntress I, Harrell E, Peng X. Tumor Necrosis Factor Alpha-Induced Interleukin-1 Alpha Synthesis and Cell Death Is Increased in Mouse Epithelial Cells Infected With Chlamydia muridarum. J Infect Dis. 2021 08 16; 224(12 Suppl 2):S47-S55.
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Gyorke CE, Kollipara A, Allen J, Zhang Y, Ezzell JA, Darville T, Montgomery SA, Nagarajan UM. IL-1a Is Essential for Oviduct Pathology during Genital Chlamydial Infection in Mice. J Immunol. 2020 12 01; 205(11):3037-3049.
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Mehta S, Akhtar S, Porter RM, ?nnerfjord P, Bajpayee AG. Interleukin-1 receptor antagonist (IL-1Ra) is more effective in suppressing cytokine-induced catabolism in cartilage-synovium co-culture than in cartilage monoculture. Arthritis Res Ther. 2019 11 13; 21(1):238.
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Archer NK, Jo JH, Lee SK, Kim D, Smith B, Ortines RV, Wang Y, Marchitto MC, Ravipati A, Cai SS, Dillen CA, Liu H, Miller RJ, Ashbaugh AG, Uppal AS, Oyoshi MK, Malhotra N, Hoff S, Garza LA, Kong HH, Segre JA, Geha RS, Miller LS. Injury, dysbiosis, and filaggrin deficiency drive skin inflammation through keratinocyte IL-1a release. J Allergy Clin Immunol. 2019 04; 143(4):1426-1443.e6.
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Makhoul I, Griffin RJ, Siegel E, Lee J, Dhakal I, Raj V, Jamshidi-Parsian A, Klimberg S, Hutchins LF, Kadlubar S. High-circulating Tie2 Is Associated With Pathologic Complete Response to Chemotherapy and Antiangiogenic Therapy in Breast Cancer. Am J Clin Oncol. 2016 06; 39(3):248-54.
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