 alpha-Crystallin B Chain
"alpha-Crystallin B Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE.
| Descriptor ID |
D038203
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| MeSH Number(s) |
D12.776.306.366.100.300 D12.776.580.157.300
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| Concept/Terms |
alpha-Crystallin B Chain- alpha-Crystallin B Chain
- B Chain, alpha-Crystallin
- alpha Crystallin B Chain
- alpha-Crystallin, B Subunit
- B Subunit alpha-Crystallin
- alpha Crystallin, B Subunit
- Rosenthal Fiber Component
- alpha B-Crystallin
- alpha B Crystallin
- Crystallins, alpha B Chain
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Below are MeSH descriptors whose meaning is more general than "alpha-Crystallin B Chain".
Below are MeSH descriptors whose meaning is more specific than "alpha-Crystallin B Chain".
This graph shows the total number of publications written about "alpha-Crystallin B Chain" by people in UAMS Profiles by year, and whether "alpha-Crystallin B Chain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2011 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "alpha-Crystallin B Chain" by people in Profiles over the past ten years.
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Lynch JM, Li B, Katoli P, Xiang C, Leehy B, Rangaswamy N, Saenz-Vash V, Wang YK, Lei H, Nicholson TB, Meredith E, Rice DS, Prasanna G, Chen A. Binding of a glaucoma-associated myocilin variant to the aB-crystallin chaperone impedes protein clearance in trabecular meshwork cells. J Biol Chem. 2018 12 28; 293(52):20137-20156.
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Kore RA, Abraham EC. Phosphorylation negatively regulates exosome mediated secretion of cryAB in glioma cells. Biochim Biophys Acta. 2016 Feb; 1863(2):368-77.
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Kore RA, Abraham EC. Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Biochem Biophys Res Commun. 2014 Oct 24; 453(3):326-31.
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