 Pilocarpine
"Pilocarpine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
| Descriptor ID |
D010862
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| MeSH Number(s) |
D03.132.672
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| Concept/Terms |
Pilocarpine Nitrate- Pilocarpine Nitrate
- Nitrate, Pilocarpine
- Pilocarpine Mononitrate, (3S-cis)-Isomer
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Below are MeSH descriptors whose meaning is more general than "Pilocarpine".
Below are MeSH descriptors whose meaning is more specific than "Pilocarpine".
This graph shows the total number of publications written about "Pilocarpine" by people in UAMS Profiles by year, and whether "Pilocarpine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2020 | 0 | 2 | 2 | | 2017 | 0 | 1 | 1 | | 2016 | 1 | 1 | 2 | | 2015 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pilocarpine" by people in Profiles over the past ten years.
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Phelan KD, Shwe UT, Wu H, Zheng F. Investigating Contributions of Canonical Transient Receptor Potential Channel 3 to Hippocampal Hyperexcitability and Seizure-Induced Neuronal Cell Death. Int J Mol Sci. 2024 Jun 06; 25(11).
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Seo GY, Neal ES, Han F, Vidovic D, Nooru-Mohamed F, Dienel GA, Sullivan MA, Borges K. Brain glycogen content is increased in the acute and interictal chronic stages of the mouse pilocarpine model of epilepsy. Epilepsia Open. 2022 06; 7(2):361-367.
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Ustaoglu M, Masoumpour M, Sanvicente C, Gulati V, Razeghinejad R. Comparing the trabecular outflow by the response to topical pilocarpine in patients with and without glaucoma filtering surgery. Jpn J Ophthalmol. 2020 Nov; 64(6):591-596.
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Cozart MA, Phelan KD, Wu H, Mu S, Birnbaumer L, Rusch NJ, Zheng F. Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus. Sci Rep. 2020 01 21; 10(1):812.
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Schartz ND, Wyatt-Johnson SK, Price LR, Colin SA, Brewster AL. Status epilepticus triggers long-lasting activation of complement C1q-C3 signaling in the hippocampus that correlates with seizure frequency in experimental epilepsy. Neurobiol Dis. 2018 Jan; 109(Pt A):163-173.
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Phelan KD, Shwe UT, Cozart MA, Wu H, Mock MM, Abramowitz J, Birnbaumer L, Zheng F. TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice. Epilepsia. 2017 02; 58(2):247-254.
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Schartz ND, Herr SA, Madsen L, Butts SJ, Torres C, Mendez LB, Brewster AL. Spatiotemporal profile of Map2 and microglial changes in the hippocampal CA1 region following pilocarpine-induced status epilepticus. Sci Rep. 2016 05 04; 6:24988.
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Phelan KD, Shwe UT, Williams DK, Greenfield LJ, Zheng F. Pilocarpine-induced status epilepticus in mice: A comparison of spectral analysis of electroencephalogram and behavioral grading using the Racine scale. Epilepsy Res. 2015 Nov; 117:90-6.
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