 Sarcopenia
"Sarcopenia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles.
| Descriptor ID |
D055948
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| MeSH Number(s) |
C10.597.613.612.500 C23.300.070.500.500 C23.888.592.608.612.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sarcopenia".
Below are MeSH descriptors whose meaning is more specific than "Sarcopenia".
This graph shows the total number of publications written about "Sarcopenia" by people in UAMS Profiles by year, and whether "Sarcopenia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 2 | 1 | 3 | | 2024 | 4 | 2 | 6 | | 2023 | 1 | 0 | 1 | | 2022 | 3 | 0 | 3 | | 2021 | 4 | 1 | 5 | | 2020 | 4 | 2 | 6 | | 2019 | 4 | 1 | 5 | | 2018 | 2 | 3 | 5 | | 2017 | 2 | 1 | 3 | | 2016 | 4 | 0 | 4 | | 2015 | 2 | 4 | 6 | | 2014 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2012 | 4 | 0 | 4 | | 2010 | 1 | 2 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Sarcopenia" by people in Profiles over the past ten years.
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Prokopidis K, Moriarty F, Bahat G, McLean J, Church DD, Patel HP. The Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta-Analysis. J Cachexia Sarcopenia Muscle. 2025 Jun; 16(3):e13799.
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Bose C, Megyesi J, Karaduta O, Singh SP, Swaminathan S, Shah SV. Iron Chelation Prevents Age-Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging. J Cachexia Sarcopenia Muscle. 2025 Feb; 16(1):e13678.
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Bosoi CR, Kumar A, Oliveira MM, Welch N, Cl?ment MA, Tremblay M, Ten-Have GAM, Engelen MPKJ, B?meur C, Deutz NEP, Dasarathy S, Rose CF. Attenuating hyperammonemia preserves protein synthesis and muscle mass via restoration of perturbed metabolic pathways in bile duct-ligated rats. Metab Brain Dis. 2025 Jan 23; 40(1):110.
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Baim-Lance A, Cooley S, Yoo-Jeong M, Ances B, Duque G, Ellis RJ, Flexner C, Pence BW, Plankey M, Mullins JD, Sun J, Thames AD, Margolick JB, Moore DJ, Erlandson KM. Current Challenges, Solutions, and Novel Directions in Research and Clinical Care: Proceedings From the 14th Annual International Workshop on HIV and Aging. J Gerontol A Biol Sci Med Sci. 2024 Dec 11; 80(1).
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Hao W, Huang X, Liang R, Yang C, Huang Z, Chen Y, Lu WW, Chen Y. Association between the Geriatric Nutritional Risk Index and sarcopenia in American adults aged 45 and older. Nutrition. 2025 Mar; 131:112628.
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Olson SL, Polineni P, Schwartz WAH, Thuluvath AJ, Duarte-Rojo A, Ladner DP. Comparing Functional Frailty and Radiographic Sarcopenia as Predictors of Outcomes After Liver Transplant. Clin Transplant. 2024 Jul; 38(7):e15412.
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Ford KL, Sawyer MB, Ghosh S, Trottier CF, Disi IR, Easaw J, Mulder K, Koski S, Porter Starr KN, Bales CW, Arends J, Siervo M, Deutz N, Prado CM. Feasibility of two levels of protein intake in patients with colorectal cancer: findings from the Protein Recommendation to Increase Muscle (PRIMe) randomized controlled pilot trial. ESMO Open. 2024 Jul; 9(7):103604.
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Thuluvath AJ, Forsgren MF, Ladner DP, Tevar AD, Duarte-Rojo A. Utilizing a novel MRI technique to identify adverse muscle composition in end-stage liver disease: A pilot study. Ann Hepatol. 2024 Jul-Aug; 29(4):101508.
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Prabakaran AD, McFarland K, Miz K, Durumutla HB, Piczer K, El Abdellaoui Soussi F, Latimer H, Werbrich C, Chung HJ, Blair NS, Millay DP, Morris AJ, Prideaux B, Finck BN, Quattrocelli M. Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1a/Lipin1 axis in an aging-related sarcopenia model. J Clin Invest. 2024 May 03; 134(11).
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Campbell WW, Deutz NEP, Volpi E, Apovian CM. Nutritional Interventions: Dietary Protein Needs and Influences on Skeletal Muscle of Older Adults. J Gerontol A Biol Sci Med Sci. 2023 06 16; 78(Suppl 1):67-72.
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Salles J, Chanet A, Guillet C, Vaes AM, Brouwer-Brolsma EM, Rocher C, Giraudet C, Patrac V, Meugnier E, Montaurier C, Denis P, Le Bacquer O, Blot A, Jourdan M, Luiking Y, Furber M, Van Dijk M, Tardif N, Yves Boirie Y, Walrand S. Vitamin D status modulates mitochondrial oxidative capacities in skeletal muscle: role in sarcopenia. Commun Biol. 2022 11 24; 5(1):1288.
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Attaway A, Welch N, Dasarathy D, Amaya-Hughley J, Bellar A, Biehl M, Dugar S, Engelen MPKJ, Zein J, Dasarathy S. Acute skeletal muscle loss in SARS-CoV-2 infection contributes to poor clinical outcomes in COVID-19 patients. J Cachexia Sarcopenia Muscle. 2022 10; 13(5):2436-2446.
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Perisetti A, Goyal H, Yendala R, Chandan S, Tharian B, Thandassery RB. Sarcopenia in hepatocellular carcinoma: Current knowledge and future directions. World J Gastroenterol. 2022 Jan 28; 28(4):432-448.
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Banks NF, Rogers EM, Church DD, Ferrando AA, Jenkins NDM. The contributory role of vascular health in age-related anabolic resistance. J Cachexia Sarcopenia Muscle. 2022 02; 13(1):114-127.
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Kortebein P. Physiatric Evaluation and Management to Optimize the Care of Older Adults at Risk for Sarcopenia. Am J Phys Med Rehabil. 2021 09 01; 100(9):e136-e137.
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Karlsson ES, Gr?nstedt HK, Fax?n-Irving G, Franz?n E, Luiking YC, Seiger ?, Vikstr?m S, Wimo A, Cederholm TE, Bostr?m AM. Response and Adherence of Nursing Home Residents to a Nutrition/Exercise Intervention. J Am Med Dir Assoc. 2021 09; 22(9):1939-1945.e3.
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Attaway AH, Welch N, Yadav R, Bellar A, Hatipoglu U, Meli Y, Engelen MPKJ, Zein J, Dasarathy S. Quantitative Computed Tomography Assessment of Pectoralis and Erector Spinae Muscle Area and Disease Severity in Chronic Obstructive Pulmonary Disease Referred for Lung Volume Reduction. COPD. 2021 04; 18(2):191-200.
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Fax?n-Irving G, Luiking Y, Gr?nstedt H, Franz?n E, Seiger ?, Vikstr?m S, Wimo A, Bostr?m AM, Cederholm T. Do Malnutrition, Sarcopenia and Frailty Overlap in Nursing-Home Residents? J Frailty Aging. 2021; 10(1):17-21.
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Hirsch KR, Church DD, Kim IY, Park S, Wolfe RR, Ferrando AA. Comparison of basal whole-body protein kinetics and muscle protein synthesis between young and older adults. Physiol Rep. 2020 12; 8(23):e14633.
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Bose C, Alves I, Singh P, Palade PT, Carvalho E, B?rsheim E, Jun SR, Cheema A, Boerma M, Awasthi S, Singh SP. Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling. Aging Cell. 2020 11; 19(11):e13261.
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Salim TI, Nestlerode LC, Lucatorto EL, Wasserman TL, Din HA, Landsittel DP, Tevar AD, Johnson JT, Duarte-Rojo A, Dunn MA. Frailty as Tested by Gait Speed Is a Risk Factor for Liver Transplant Respiratory Complications. Am J Gastroenterol. 2020 06; 115(6):859-866.
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Ligthart-Melis GC, Luiking YC, Kakourou A, Cederholm T, Maier AB, de van der Schueren MAE. Frailty, Sarcopenia, and Malnutrition Frequently (Co-)occur in Hospitalized Older Adults: A Systematic Review and Meta-analysis. J Am Med Dir Assoc. 2020 09; 21(9):1216-1228.
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Wojzischke J, van Wijngaarden J, van den Berg C, Cetinyurek-Yavuz A, Diekmann R, Luiking Y, Bauer J. Nutritional status and functionality in geriatric rehabilitation patients: a systematic review and meta-analysis. Eur Geriatr Med. 2020 04; 11(2):195-207.
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Bagheri R, Moghadam BH, Church DD, Tinsley GM, Eskandari M, Moghadam BH, Motevalli MS, Baker JS, Robergs RA, Wong A. The effects of concurrent training order on body composition and serum concentrations of follistatin, myostatin and GDF11 in sarcopenic elderly men. Exp Gerontol. 2020 05; 133:110869.
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Tandon P, Dunn MA, Duarte-Rojo A. Resistance Training Reduces Risk of Sarcopenia in Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2020 05; 18(5):1036-1039.
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Moro T, Brightwell CR, Phalen DE, McKenna CF, Lane SJ, Porter C, Volpi E, Rasmussen BB, Fry CS. Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults. Exp Gerontol. 2019 11; 127:110723.
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van der Meij BS, De Groot LM, Deutz NEP, Engelen MPKJ. Effects of acute oral feeding on protein metabolism and muscle protein synthesis in individuals with cancer. Nutrition. 2019 Nov - Dec; 67-68:110531.
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Liberman K, Njemini R, Luiking Y, Forti LN, Verlaan S, Bauer JM, Memelink R, Brandt K, Donini LM, Maggio M, Mets T, Wijers SLJ, Sieber C, Cederholm T, Bautmans I. Thirteen weeks of supplementation of vitamin D and leucine-enriched whey protein nutritional supplement attenuates chronic low-grade inflammation in sarcopenic older adults: the PROVIDE study. Aging Clin Exp Res. 2019 Jun; 31(6):845-854.
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Ter Borg S, Luiking YC, van Helvoort A, Boirie Y, Schols JMGA, de Groot CPGM. Low Levels of Branched Chain Amino Acids, Eicosapentaenoic Acid and Micronutrients Are Associated with Low Muscle Mass, Strength and Function in Community-Dwelling Older Adults. J Nutr Health Aging. 2019; 23(1):27-34.
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Tandon P, Ismond KP, Riess K, Duarte-Rojo A, Al-Judaibi B, Dunn MA, Holman J, Howes N, Haykowsky MJF, Josbeno DA, McNeely M. Exercise in cirrhosis: Translating evidence and experience to practice. J Hepatol. 2018 11; 69(5):1164-1177.
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Verschuren O, Smorenburg ARP, Luiking Y, Bell K, Barber L, Peterson MD. Determinants of muscle preservation in individuals with cerebral palsy across the lifespan: a narrative review of the literature. J Cachexia Sarcopenia Muscle. 2018 06; 9(3):453-464.
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Duarte-Rojo A, Ruiz-Marg?in A, Monta?o-Loza AJ, Mac?as-Rodr?guez RU, Ferrando A, Kim WR. Exercise and physical activity for patients with end-stage liver disease: Improving functional status and sarcopenia while on the transplant waiting list. Liver Transpl. 2018 01; 24(1):122-139.
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Coker RH, Wolfe RR. Weight Loss Strategies in the Elderly: A Clinical Conundrum. Obesity (Silver Spring). 2018 01; 26(1):22-28.
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Mijnarends DM, Luiking YC, Halfens RJG, Evers SMAA, Lenaerts ELA, Verlaan S, Wallace M, Schols JMGA, Meijers JMM. Muscle, Health and Costs: A Glance at their Relationship. J Nutr Health Aging. 2018; 22(7):766-773.
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Deutz NEP, Thaden JJ, Ten Have GAM, Walker DK, Engelen MPKJ. Metabolic phenotyping using kinetic measurements in young and older healthy adults. Metabolism. 2018 01; 78:167-178.
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Kumar A, Davuluri G, Silva RNE, Engelen MPKJ, Ten Have GAM, Prayson R, Deutz NEP, Dasarathy S. Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis. Hepatology. 2017 06; 65(6):2045-2058.
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Cesari M, Landi F, Calvani R, Cherubini A, Di Bari M, Kortebein P, Del Signore S, Le Lain R, Vellas B, Pahor M, Roubenoff R, Bernabei R, Marzetti E. Rationale for a preliminary operational definition of physical frailty and sarcopenia in the SPRINTT trial. Aging Clin Exp Res. 2017 Feb; 29(1):81-88.
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van Dijk M, Nagel J, Dijk FJ, Salles J, Verlaan S, Walrand S, van Norren K, Luiking Y. Sarcopenia in older mice is characterized by a decreased anabolic response to a protein meal. Arch Gerontol Geriatr. 2017 Mar - Apr; 69:134-143.
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Kramer IF, Verdijk LB, Hamer HM, Verlaan S, Luiking YC, Kouw IWK, Senden JM, van Kranenburg J, Gijsen AP, Bierau J, Poeze M, van Loon LJC. Both basal and post-prandial muscle protein synthesis rates, following the ingestion of a leucine-enriched whey protein supplement, are not impaired in sarcopenic older males. Clin Nutr. 2017 10; 36(5):1440-1449.
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Ter Borg S, Verlaan S, de Groot LC, de Vries JH, Meijboom S, Mijnarends DM, Luiking YC, Schols JM. Response to the 'Letter to the Editor on?the Maastricht Sarcopenia Study'. J Am Med Dir Assoc. 2016 06 01; 17(6):557-8.
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Ter Borg S, de Groot LC, Mijnarends DM, de Vries JH, Verlaan S, Meijboom S, Luiking YC, Schols JM. Differences in Nutrient Intake and Biochemical Nutrient Status Between Sarcopenic and Nonsarcopenic Older Adults-Results From?the Maastricht Sarcopenia Study. J Am Med Dir Assoc. 2016 05 01; 17(5):393-401.
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Ahmadi H, Montie JE, Weizer AZ, Morgan T, Montgomery JS, Lee CT. Patient Psoas Muscle Mass as a Predictor of Complications and Survival After Radical Cystectomy. Curr Urol Rep. 2015 Nov; 16(11):79.
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Carson JA, Manolagas SC. Effects of sex steroids on bones and muscles: Similarities, parallels, and putative interactions in health and disease. Bone. 2015 Nov; 80:67-78.
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