 Sarcopenia
"Sarcopenia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles.
| Descriptor ID |
D055948
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| MeSH Number(s) |
C10.597.613.612.500 C23.300.070.500.500 C23.888.592.608.612.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sarcopenia".
Below are MeSH descriptors whose meaning is more specific than "Sarcopenia".
This graph shows the total number of publications written about "Sarcopenia" by people in UAMS Profiles by year, and whether "Sarcopenia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 2 | 1 | 3 | | 2023 | 1 | 0 | 1 | | 2022 | 4 | 0 | 4 | | 2021 | 5 | 2 | 7 | | 2020 | 7 | 3 | 10 | | 2019 | 7 | 1 | 8 | | 2018 | 3 | 3 | 6 | | 2017 | 4 | 1 | 5 | | 2016 | 4 | 2 | 6 | | 2015 | 2 | 4 | 6 | | 2014 | 3 | 1 | 4 | | 2013 | 1 | 0 | 1 | | 2012 | 4 | 0 | 4 | | 2010 | 1 | 2 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Sarcopenia" by people in Profiles over the past ten years.
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Olson SL, Polineni P, Schwartz WAH, Thuluvath AJ, Duarte-Rojo A, Ladner DP. Comparing Functional Frailty and Radiographic Sarcopenia as Predictors of Outcomes After Liver Transplant. Clin Transplant. 2024 Jul; 38(7):e15412.
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Ford KL, Sawyer MB, Ghosh S, Trottier CF, Disi IR, Easaw J, Mulder K, Koski S, Porter Starr KN, Bales CW, Arends J, Siervo M, Deutz N, Prado CM. Feasibility of two levels of protein intake in patients with colorectal cancer: findings from the Protein Recommendation to Increase Muscle (PRIMe) randomized controlled pilot trial. ESMO Open. 2024 Jul; 9(7):103604.
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Thuluvath AJ, Forsgren MF, Ladner DP, Tevar AD, Duarte-Rojo A. Utilizing a novel MRI technique to identify adverse muscle composition in end-stage liver disease: A pilot study. Ann Hepatol. 2024 Jul-Aug; 29(4):101508.
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Campbell WW, Deutz NEP, Volpi E, Apovian CM. Nutritional Interventions: Dietary Protein Needs and Influences on Skeletal Muscle of Older Adults. J Gerontol A Biol Sci Med Sci. 2023 06 16; 78(Suppl 1):67-72.
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Salles J, Chanet A, Guillet C, Vaes AM, Brouwer-Brolsma EM, Rocher C, Giraudet C, Patrac V, Meugnier E, Montaurier C, Denis P, Le Bacquer O, Blot A, Jourdan M, Luiking Y, Furber M, Van Dijk M, Tardif N, Yves Boirie Y, Walrand S. Vitamin D status modulates mitochondrial oxidative capacities in skeletal muscle: role in sarcopenia. Commun Biol. 2022 11 24; 5(1):1288.
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Attaway A, Welch N, Dasarathy D, Amaya-Hughley J, Bellar A, Biehl M, Dugar S, Engelen MPKJ, Zein J, Dasarathy S. Acute skeletal muscle loss in SARS-CoV-2 infection contributes to poor clinical outcomes in COVID-19 patients. J Cachexia Sarcopenia Muscle. 2022 10; 13(5):2436-2446.
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Park S, Chang Y, Wolfe RR, Kim IY. Prevention of Loss of Muscle Mass and Function in Older Adults during COVID-19 Lockdown: Potential Role of Dietary Essential Amino Acids. Int J Environ Res Public Health. 2022 07 01; 19(13).
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Perisetti A, Goyal H, Yendala R, Chandan S, Tharian B, Thandassery RB. Sarcopenia in hepatocellular carcinoma: Current knowledge and future directions. World J Gastroenterol. 2022 Jan 28; 28(4):432-448.
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Banks NF, Rogers EM, Church DD, Ferrando AA, Jenkins NDM. The contributory role of vascular health in age-related anabolic resistance. J Cachexia Sarcopenia Muscle. 2022 02; 13(1):114-127.
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Karanth SD, Washington C, Cheng TD, Zhou D, Leeuwenburgh C, Braithwaite D, Zhang D. Inflammation in Relation to Sarcopenia and Sarcopenic Obesity among Older Adults Living with Chronic Comorbidities: Results from the National Health and Nutrition Examination Survey 1999-2006. Nutrients. 2021 Nov 05; 13(11).
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Kortebein P. Physiatric Evaluation and Management to Optimize the Care of Older Adults at Risk for Sarcopenia. Am J Phys Med Rehabil. 2021 09 01; 100(9):e136-e137.
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Stangl-Kremser J, Ahmadi H, Derstine B, Wang SC, Englesbe MJ, Daignault-Newton S, Chernin AS, Montgomery JS, Palapattu GS, Lee CT. Psoas Muscle Mass can Predict Postsurgical Outcomes in Patients Who Undergo Radical Cystectomy and Urinary Diversion Reconstruction. Urology. 2021 12; 158:142-149.
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Karlsson ES, Gr?nstedt HK, Fax?n-Irving G, Franz?n E, Luiking YC, Seiger ?, Vikstr?m S, Wimo A, Cederholm TE, Bostr?m AM. Response and Adherence of Nursing Home Residents to a Nutrition/Exercise Intervention. J Am Med Dir Assoc. 2021 09; 22(9):1939-1945.e3.
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Attaway AH, Welch N, Yadav R, Bellar A, Hatipoglu U, Meli Y, Engelen MPKJ, Zein J, Dasarathy S. Quantitative Computed Tomography Assessment of Pectoralis and Erector Spinae Muscle Area and Disease Severity in Chronic Obstructive Pulmonary Disease Referred for Lung Volume Reduction. COPD. 2021 04; 18(2):191-200.
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Fax?n-Irving G, Luiking Y, Gr?nstedt H, Franz?n E, Seiger ?, Vikstr?m S, Wimo A, Bostr?m AM, Cederholm T. Do Malnutrition, Sarcopenia and Frailty Overlap in Nursing-Home Residents? J Frailty Aging. 2021; 10(1):17-21.
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Hirsch KR, Church DD, Kim IY, Park S, Wolfe RR, Ferrando AA. Comparison of basal whole-body protein kinetics and muscle protein synthesis between young and older adults. Physiol Rep. 2020 12; 8(23):e14633.
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Bose C, Alves I, Singh P, Palade PT, Carvalho E, B?rsheim E, Jun SR, Cheema A, Boerma M, Awasthi S, Singh SP. Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling. Aging Cell. 2020 11; 19(11):e13261.
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Wu H, Jang J, Dridi S, Ferrando AA, Wolfe RR, Kim IY, Baum JI. Net protein balance correlates with expression of autophagy, mitochondrial biogenesis, and fat metabolism-related genes in skeletal muscle from older adults. Physiol Rep. 2020 10; 8(19):e14575.
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Ruiz-Marg?in A, Xie JJ, Rom?n-Calleja BM, Pauly M, White MG, Chapa-Ibarg?engoitia M, Campos-Murgu?a A, Gonz?lez-Regueiro JA, Macias-Rodr?guez RU, Duarte-Rojo A. Phase Angle From Bioelectrical Impedance for the Assessment of Sarcopenia in Cirrhosis With or Without Ascites. Clin Gastroenterol Hepatol. 2021 09; 19(9):1941-1949.e2.
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Salim TI, Nestlerode LC, Lucatorto EL, Wasserman TL, Din HA, Landsittel DP, Tevar AD, Johnson JT, Duarte-Rojo A, Dunn MA. Frailty as Tested by Gait Speed Is a Risk Factor for Liver Transplant Respiratory Complications. Am J Gastroenterol. 2020 06; 115(6):859-866.
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Dunn MA, Rogal SS, Duarte-Rojo A, Lai JC. Physical Function, Physical Activity, and Quality of Life After Liver Transplantation. Liver Transpl. 2020 05; 26(5):702-708.
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Ligthart-Melis GC, Luiking YC, Kakourou A, Cederholm T, Maier AB, de van der Schueren MAE. Frailty, Sarcopenia, and Malnutrition Frequently (Co-)occur in Hospitalized Older Adults: A Systematic Review and Meta-analysis. J Am Med Dir Assoc. 2020 09; 21(9):1216-1228.
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Bauer JM, Miku?ov? L, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, Mets T, Wijers SLJ, Garthoff JA, Luiking Y, Sieber C, Cederholm T. Safety and tolerability of 6-month supplementation with a vitamin D, calcium and leucine-enriched whey protein medical nutrition drink in sarcopenic older adults. Aging Clin Exp Res. 2020 Aug; 32(8):1501-1514.
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Wojzischke J, van Wijngaarden J, van den Berg C, Cetinyurek-Yavuz A, Diekmann R, Luiking Y, Bauer J. Nutritional status and functionality in geriatric rehabilitation patients: a systematic review and meta-analysis. Eur Geriatr Med. 2020 04; 11(2):195-207.
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Bagheri R, Moghadam BH, Church DD, Tinsley GM, Eskandari M, Moghadam BH, Motevalli MS, Baker JS, Robergs RA, Wong A. The effects of concurrent training order on body composition and serum concentrations of follistatin, myostatin and GDF11 in sarcopenic elderly men. Exp Gerontol. 2020 05; 133:110869.
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Tandon P, Dunn MA, Duarte-Rojo A. Resistance Training Reduces Risk of Sarcopenia in Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2020 05; 18(5):1036-1039.
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Moro T, Brightwell CR, Phalen DE, McKenna CF, Lane SJ, Porter C, Volpi E, Rasmussen BB, Fry CS. Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults. Exp Gerontol. 2019 11; 127:110723.
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Carey EJ, Lai JC, Sonnenday C, Tapper EB, Tandon P, Duarte-Rojo A, Dunn MA, Tsien C, Kallwitz ER, Ng V, Dasarathy S, Kappus M, Bashir MR, Montano-Loza AJ. A North American Expert Opinion Statement on Sarcopenia in Liver Transplantation. Hepatology. 2019 11; 70(5):1816-1829.
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van der Meij BS, De Groot LM, Deutz NEP, Engelen MPKJ. Effects of acute oral feeding on protein metabolism and muscle protein synthesis in individuals with cancer. Nutrition. 2019 Nov - Dec; 67-68:110531.
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Liberman K, Njemini R, Luiking Y, Forti LN, Verlaan S, Bauer JM, Memelink R, Brandt K, Donini LM, Maggio M, Mets T, Wijers SLJ, Sieber C, Cederholm T, Bautmans I. Thirteen weeks of supplementation of vitamin D and leucine-enriched whey protein nutritional supplement attenuates chronic low-grade inflammation in sarcopenic older adults: the PROVIDE study. Aging Clin Exp Res. 2019 Jun; 31(6):845-854.
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Kortebein P. Terminology and Classification of Clinically Relevant Muscle Wasting Disease. Am J Phys Med Rehabil. 2019 04; 98(4):e35.
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Ter Borg S, Luiking YC, van Helvoort A, Boirie Y, Schols JMGA, de Groot CPGM. Low Levels of Branched Chain Amino Acids, Eicosapentaenoic Acid and Micronutrients Are Associated with Low Muscle Mass, Strength and Function in Community-Dwelling Older Adults. J Nutr Health Aging. 2019; 23(1):27-34.
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Deutz NEP, Ashurst I, Ballesteros MD, Bear DE, Cruz-Jentoft AJ, Genton L, Landi F, Laviano A, Norman K, Prado CM. The Underappreciated Role of Low Muscle Mass in the Management of Malnutrition. J Am Med Dir Assoc. 2019 01; 20(1):22-27.
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Tandon P, Ismond KP, Riess K, Duarte-Rojo A, Al-Judaibi B, Dunn MA, Holman J, Howes N, Haykowsky MJF, Josbeno DA, McNeely M. Exercise in cirrhosis: Translating evidence and experience to practice. J Hepatol. 2018 11; 69(5):1164-1177.
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Bhanji RA, Moctezuma-Velazquez C, Duarte-Rojo A, Ebadi M, Ghosh S, Rose C, Montano-Loza AJ. Myosteatosis and sarcopenia are associated with hepatic encephalopathy in patients with cirrhosis. Hepatol Int. 2018 Jul; 12(4):377-386.
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Verschuren O, Smorenburg ARP, Luiking Y, Bell K, Barber L, Peterson MD. Determinants of muscle preservation in individuals with cerebral palsy across the lifespan: a narrative review of the literature. J Cachexia Sarcopenia Muscle. 2018 06; 9(3):453-464.
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Mijnarends DM, Luiking YC, Halfens RJG, Evers SMAA, Lenaerts ELA, Verlaan S, Wallace M, Schols JMGA, Meijers JMM. Muscle, Health and Costs: A Glance at their Relationship. J Nutr Health Aging. 2018; 22(7):766-773.
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Duarte-Rojo A, Ruiz-Marg?in A, Monta?o-Loza AJ, Mac?as-Rodr?guez RU, Ferrando A, Kim WR. Exercise and physical activity for patients with end-stage liver disease: Improving functional status and sarcopenia while on the transplant waiting list. Liver Transpl. 2018 01; 24(1):122-139.
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Coker RH, Wolfe RR. Weight Loss Strategies in the Elderly: A Clinical Conundrum. Obesity (Silver Spring). 2018 01; 26(1):22-28.
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Deutz NEP, Thaden JJ, Ten Have GAM, Walker DK, Engelen MPKJ. Metabolic phenotyping using kinetic measurements in young and older healthy adults. Metabolism. 2018 01; 78:167-178.
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Standley RA, Distefano G, Pereira SL, Tian M, Kelly OJ, Coen PM, Deutz NEP, Wolfe RR, Goodpaster BH. Effects of ?-hydroxy-?-methylbutyrate on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults. J Appl Physiol (1985). 2017 Nov 01; 123(5):1092-1100.
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Kumar A, Davuluri G, Silva RNE, Engelen MPKJ, Ten Have GAM, Prayson R, Deutz NEP, Dasarathy S. Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis. Hepatology. 2017 06; 65(6):2045-2058.
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Long DE, Peck BD, Martz JL, Tuggle SC, Bush HM, McGwin G, Kern PA, Bamman MM, Peterson CA. Metformin to Augment Strength Training Effective Response in Seniors (MASTERS): study protocol for a randomized controlled trial. Trials. 2017 04 26; 18(1):192.
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Cesari M, Landi F, Calvani R, Cherubini A, Di Bari M, Kortebein P, Del Signore S, Le Lain R, Vellas B, Pahor M, Roubenoff R, Bernabei R, Marzetti E. Rationale for a preliminary operational definition of physical frailty and sarcopenia in the SPRINTT trial. Aging Clin Exp Res. 2017 Feb; 29(1):81-88.
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Figueroa A, Alvarez-Alvarado S, Jaime SJ, Johnson SA, Campbell JC, Feresin RG, Elam ML, Navaei N, Pourafshar S, Arjmandi BH. Influence of low and normal appendicular lean mass on central blood pressure and wave reflection responses to muscle metaboreflex activation in postmenopausal women. Clin Exp Pharmacol Physiol. 2016 12; 43(12):1243-1246.
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van Dijk M, Nagel J, Dijk FJ, Salles J, Verlaan S, Walrand S, van Norren K, Luiking Y. Sarcopenia in older mice is characterized by a decreased anabolic response to a protein meal. Arch Gerontol Geriatr. 2017 Mar - Apr; 69:134-143.
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Bischoff SC, Boirie Y, Cederholm T, Chourdakis M, Cuerda C, Delzenne NM, Deutz NE, Fouque D, Genton L, Gil C, Koletzko B, Leon-Sanz M, Shamir R, Singer J, Singer P, Stroebele-Benschop N, Thorell A, Weimann A, Barazzoni R. Towards a multidisciplinary approach to understand and manage obesity and related diseases. Clin Nutr. 2017 08; 36(4):917-938.
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Kramer IF, Verdijk LB, Hamer HM, Verlaan S, Luiking YC, Kouw IWK, Senden JM, van Kranenburg J, Gijsen AP, Bierau J, Poeze M, van Loon LJC. Both basal and post-prandial muscle protein synthesis rates, following the ingestion of a leucine-enriched whey protein supplement, are not impaired in sarcopenic older males. Clin Nutr. 2017 10; 36(5):1440-1449.
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Ter Borg S, Verlaan S, de Groot LC, de Vries JH, Meijboom S, Mijnarends DM, Luiking YC, Schols JM. Response to the 'Letter to the Editor on?the Maastricht Sarcopenia Study'. J Am Med Dir Assoc. 2016 06 01; 17(6):557-8.
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Ter Borg S, de Groot LC, Mijnarends DM, de Vries JH, Verlaan S, Meijboom S, Luiking YC, Schols JM. Differences in Nutrient Intake and Biochemical Nutrient Status Between Sarcopenic and Nonsarcopenic Older Adults-Results From?the Maastricht Sarcopenia Study. J Am Med Dir Assoc. 2016 05 01; 17(5):393-401.
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Ahmadi H, Montie JE, Weizer AZ, Morgan T, Montgomery JS, Lee CT. Patient Psoas Muscle Mass as a Predictor of Complications and Survival After Radical Cystectomy. Curr Urol Rep. 2015 Nov; 16(11):79.
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Carson JA, Manolagas SC. Effects of sex steroids on bones and muscles: Similarities, parallels, and putative interactions in health and disease. Bone. 2015 Nov; 80:67-78.
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Wolfe RR. Update on protein intake: importance of milk proteins for health status of the elderly. Nutr Rev. 2015 Aug; 73 Suppl 1:41-7.
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Figueroa A, Jaime SJ, Johnson SA, Alvarez-Alvarado S, Campbell JC, Feresin RG, Elam ML, Arjmandi BH. Impact of age on aortic wave reflection responses to metaboreflex activation and its relationship with leg lean mass in post-menopausal women. Exp Gerontol. 2015 Oct; 70:119-24.
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Lee JD, Fry CS, Mula J, Kirby TJ, Jackson JR, Liu F, Yang L, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Aged Muscle Demonstrates Fiber-Type Adaptations in Response to Mechanical Overload, in the Absence of Myofiber Hypertrophy, Independent of Satellite Cell Abundance. J Gerontol A Biol Sci Med Sci. 2016 Apr; 71(4):461-7.
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Tsien C, Davuluri G, Singh D, Allawy A, Ten Have GA, Thapaliya S, Schulze JM, Barnes D, McCullough AJ, Engelen MP, Deutz NE, Dasarathy S. Metabolic and molecular responses to leucine-enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis. Hepatology. 2015 Jun; 61(6):2018-29.
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Mijnarends DM, Schols JM, Meijers JM, Tan FE, Verlaan S, Luiking YC, Morley JE, Halfens RJ. Instruments to assess sarcopenia and physical frailty in older people living in a community (care) setting: similarities and discrepancies. J Am Med Dir Assoc. 2015 Apr; 16(4):301-8.
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Fry CS, Lee JD, Mula J, Kirby TJ, Jackson JR, Liu F, Yang L, Mendias CL, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia. Nat Med. 2015 Jan; 21(1):76-80.
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