55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.

Descriptor ID	D015704
MeSH Number(s)	D12.776.543.750.705.852.420.810.500 D12.776.543.750.925.700.025 D23.050.301.264.035.104 D23.050.301.264.894.100 D23.101.100.110.104 D23.101.100.894.100
Concept/Terms	Antigens, CD4 Antigens, CD4 CD4 Receptors Receptors, CD4 Receptors, Surface CD4 CD4 Receptors, Surface Surface CD4 Receptors T4 Antigens, T-Cell Antigens, T-Cell T4 T-Cell T4 Antigens T4 Antigens, T Cell Surface CD4 Receptor CD4 Receptor, Surface CD4 Antigen Antigen, CD4 CD4 Antigens CD4 Molecule

Below are MeSH descriptors whose meaning is more general than "Antigens, CD4".

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Below are MeSH descriptors whose meaning is more specific than "Antigens, CD4".