 Potassium Channel Blockers
"Potassium Channel Blockers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.
| Descriptor ID |
D026902
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| MeSH Number(s) |
D27.505.519.562.500 D27.505.954.411.645
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Potassium Channel Blockers".
Below are MeSH descriptors whose meaning is more specific than "Potassium Channel Blockers".
This graph shows the total number of publications written about "Potassium Channel Blockers" by people in UAMS Profiles by year, and whether "Potassium Channel Blockers" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 3 | 0 | 3 | | 2016 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2003 | 0 | 2 | 2 |
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Below are the most recent publications written about "Potassium Channel Blockers" by people in Profiles over the past ten years.
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Slavov S, Stoyanova-Slavova I, Li S, Zhao J, Huang R, Xia M, Beger R. Why are most phospholipidosis inducers also hERG blockers? Arch Toxicol. 2017 Dec; 91(12):3885-3895.
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Huo J, Kamalakar A, Yang X, Word B, Stockbridge N, Lyn-Cook B, Pang L. Evaluation of Batch Variations in Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes from 2 Major Suppliers. Toxicol Sci. 2017 03 01; 156(1):25-38.
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Stoyanova-Slavova IB, Slavov SH, Buzatu DA, Beger RD, Wilkes JG. 3D-SDAR modeling of hERG potassium channel affinity: A case study in model design and toxicophore identification. J Mol Graph Model. 2017 03; 72:246-255.
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Joshi K, Shen L, Michaeli A, Salter M, Thibault-Messier G, Hashmi S, Eubanks JH, Cortez MA, Snead OC. Infantile spasms in down syndrome: Rescue by knockdown of the GIRK2 channel. Ann Neurol. 2016 10; 80(4):511-21.
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Burns TM, Smith GA, Allen JA, Amato AA, Arnold WD, Barohn R, Benatar M, Bird SJ, Bromberg M, Chahin N, Ciafaloni E, Cohen JA, Corse A, Crum BA, David WS, Dimberg E, Sousa EA, Donofrio PD, Dyck PJ, Engel AG, Ensrud ER, Ferrante M, Freimer M, Gable KL, Gibson S, Gilchrist JM, Goldstein JM, Gooch CL, Goodman BP, Gorelov D, Gospe SM, Goyal NA, Guidon AC, Guptill JT, Gutmann L, Gutmann L, Gwathmey K, Harati Y, Harper CM, Hehir MK, Hobson-Webb LD, Howard JF, Jackson CE, Johnson N, Jones SM, Juel VC, Kaminski HJ, Karam C, Kennelly KD, Khella S, Khoury J, Kincaid JC, Kissel JT, Kolb N, Lacomis D, Ladha S, Larriviere D, Lewis RA, Li Y, Litchy WJ, Logigian E, Lou JS, MacGowen DJ, Maselli R, Massey JM, Mauermann ML, Mathews KD, Meriggioli MN, Miller RG, Moon JS, Mozaffar T, Nations SP, Nowak RJ, Ostrow LW, Pascuzzi RM, Peltier A, Ruzhansky K, Richman DP, Ross MA, Rubin DI, Russell JA, Sachs GM, Salajegheh MK, Saperstein DS, Scelsa S, Selcen D, Shaibani A, Shieh PB, Silvestri NJ, Singleton JR, Smith BE, So YT, Solorzano G, Sorenson EJ, Srinivasen J, Tavee J, Tawil R, Thaisetthawatkul P, Thornton C, Trivedi J, Vernino S, Wang AK, Webb TA, Weiss MD, Windebank AJ, Wolfe GI. Editorial by concerned physicians: Unintended effect of the orphan drug act on the potential cost of 3,4-diaminopyridine. Muscle Nerve. 2016 Feb; 53(2):165-8.
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