An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.

Descriptor ID	D018408
MeSH Number(s)	E05.242.800
Concept/Terms	Patch-Clamp Techniques Patch-Clamp Techniques Patch Clamp Techniques Patch-Clamp Technique Technique, Patch-Clamp Techniques, Patch-Clamp Patch-Clamp Technics Patch Clamp Technics Patch-Clamp Technic Technic, Patch-Clamp Technics, Patch-Clamp Whole-Cell Recording Whole-Cell Recording Recording, Whole-Cell Recordings, Whole-Cell Whole Cell Recording Whole-Cell Recordings Voltage-Clamp Techniques Voltage-Clamp Techniques Technique, Voltage-Clamp Techniques, Voltage-Clamp Voltage Clamp Techniques Voltage-Clamp Technique Voltage-Clamp Technics Technic, Voltage-Clamp Technics, Voltage-Clamp Voltage Clamp Technics Voltage-Clamp Technic

Below are MeSH descriptors whose meaning is more general than "Patch-Clamp Techniques".

Below are MeSH descriptors whose meaning is related to "Patch-Clamp Techniques".

Below are MeSH descriptors whose meaning is more specific than "Patch-Clamp Techniques".