 1-Alkyl-2-acetylglycerophosphocholine Esterase
"1-Alkyl-2-acetylglycerophosphocholine Esterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.
| Descriptor ID |
D043203
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| MeSH Number(s) |
D08.811.277.352.100.680.750.937.249
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| Concept/Terms |
1-Alkyl-2-acetylglycerophosphocholine Esterase- 1-Alkyl-2-acetylglycerophosphocholine Esterase
- 1 Alkyl 2 acetylglycerophosphocholine Esterase
- Esterase, 1-Alkyl-2-acetylglycerophosphocholine
- PAF 2-Acetylhydrolase
- 2-Acetylhydrolase, PAF
- PAF 2 Acetylhydrolase
- PAF 2-Acylhydrolase
- PAF 2 Acylhydrolase
- Lp-PLA(2)
- PAF Acetylhydrolase II
- Acetylhydrolase II, PAF
- Platelet-Activating Factor Hydrolase
- Factor Hydrolase, Platelet-Activating
- Hydrolase, Platelet-Activating Factor
- Platelet Activating Factor Hydrolase
- Lipoprotein-Associated Phospholipase A(2)
- Lipoprotein-Associated Phospholipase A2
- Lipoprotein Associated Phospholipase A2
- Phospholipase A2, Lipoprotein-Associated
- Lp-PLA2
- Lp PLA2
- PAF Acetylhydrolase
- Acetylhydrolase, PAF
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Below are MeSH descriptors whose meaning is more general than "1-Alkyl-2-acetylglycerophosphocholine Esterase".
Below are MeSH descriptors whose meaning is more specific than "1-Alkyl-2-acetylglycerophosphocholine Esterase".
This graph shows the total number of publications written about "1-Alkyl-2-acetylglycerophosphocholine Esterase" by people in UAMS Profiles by year, and whether "1-Alkyl-2-acetylglycerophosphocholine Esterase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "1-Alkyl-2-acetylglycerophosphocholine Esterase" by people in Profiles over the past ten years.
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Ye S, Fujiwara T, Zhou J, Varughese KI, Zhao H. LIS1 Regulates Osteoclastogenesis through Modulation of M-SCF and RANKL Signaling Pathways and CDC42. Int J Biol Sci. 2016; 12(12):1488-1499.
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Chen X, Chen X, Xu Y, Yang W, Wu N, Ye H, Yang JY, Hong Q, Xin Y, Yang MQ, Deng Y, Duan S. Association of six CpG-SNPs in the inflammation-related genes with coronary heart disease. Hum Genomics. 2016 07 25; 10 Suppl 2:21.
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