 Rats, Wistar
"Rats, Wistar" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
| Descriptor ID |
D017208
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| MeSH Number(s) |
B01.050.150.900.649.865.635.505.700.900
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Rats, Wistar".
Below are MeSH descriptors whose meaning is more specific than "Rats, Wistar".
This graph shows the total number of publications written about "Rats, Wistar" by people in UAMS Profiles by year, and whether "Rats, Wistar" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2025 | 0 | 3 | 3 | | 2024 | 1 | 1 | 2 | | 2023 | 0 | 2 | 2 | | 2022 | 0 | 4 | 4 | | 2021 | 0 | 2 | 2 | | 2020 | 0 | 3 | 3 | | 2019 | 0 | 4 | 4 | | 2018 | 0 | 2 | 2 | | 2017 | 0 | 6 | 6 | | 2016 | 0 | 7 | 7 | | 2015 | 0 | 6 | 6 | | 2014 | 0 | 11 | 11 | | 2013 | 0 | 13 | 13 | | 2012 | 0 | 5 | 5 | | 2011 | 0 | 5 | 5 | | 2010 | 0 | 6 | 6 | | 2009 | 0 | 8 | 8 | | 2008 | 0 | 9 | 9 | | 2007 | 0 | 6 | 6 | | 2006 | 0 | 4 | 4 | | 2005 | 0 | 7 | 7 | | 2004 | 0 | 10 | 10 | | 2003 | 0 | 7 | 7 | | 2002 | 0 | 6 | 6 | | 2001 | 0 | 2 | 2 | | 2000 | 0 | 6 | 6 | | 1999 | 0 | 3 | 3 | | 1998 | 0 | 5 | 5 | | 1997 | 0 | 6 | 6 | | 1996 | 0 | 9 | 9 | | 1995 | 0 | 9 | 9 | | 1994 | 0 | 6 | 6 | | 1993 | 0 | 10 | 10 | | 1992 | 0 | 1 | 1 |
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Below are the most recent publications written about "Rats, Wistar" by people in Profiles over the past ten years.
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Pi H, Fu Q, Liu J, Zhou H, Wang Y. Excessive apoptosis, glycolysis, and abnormal levels of gluconeogenase in rheumatoid arthritis involves in the dysregulation of glucose metabolism: an animal model study. Autoimmunity. 2025 Dec; 58(1):2499730.
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Khalaf RR, Abouzeinab NS, Khalil MI. Effects of Lebanese Folk Herbs on Adult Male Rats: Hepatic and Renal Toxicity, Histological, and Biochemical Studies. Nutrients. 2025 Feb 28; 17(5).
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Bosoi CR, Kumar A, Oliveira MM, Welch N, Cl?ment MA, Tremblay M, Ten-Have GAM, Engelen MPKJ, B?meur C, Deutz NEP, Dasarathy S, Rose CF. Attenuating hyperammonemia preserves protein synthesis and muscle mass via restoration of perturbed metabolic pathways in bile duct-ligated rats. Metab Brain Dis. 2025 Jan 23; 40(1):110.
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Libby AE, Solt CM, Jackman MR, Sherk VD, Foright RM, Johnson GC, Nguyen TT, Breit MJ, Hulett N, Rudolph MC, Roberson PA, Wellberg EA, Jambal P, Scalzo RL, Higgins J, Kumar TR, Wierman ME, Pan Z, Shankar K, Klemm DJ, Moreau KL, Kohrt WM, MacLean PS. Effects of follicle-stimulating hormone on energy balance and tissue metabolic health after loss of ovarian function. Am J Physiol Endocrinol Metab. 2024 May 01; 326(5):E626-E639.
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El-Baz YG, Moustafa A, Ali MA, El-Desoky GE, Wabaidur SM, Iqbal A. Green synthesized silver nanoparticles for the treatment of diabetes and the related complications of hyperlipidemia and oxidative stress in diabetic rats. Exp Biol Med (Maywood). 2023 Dec; 248(23):2237-2248.
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Hulett NA, Knaub LA, Hull SE, Pott GB, Peelor R, Miller BF, Shankar K, Rudolph MC, Reusch JEB, Scalzo RL. Sex Differences in the Skeletal Muscle Response to a High Fat, High Sucrose Diet in Rats. Nutrients. 2023 Oct 19; 15(20).
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Yapca OE, Yildiz GA, Mammadov R, Kurt N, Gundogdu B, Arslan YK, Suleyman H, Cetin N. The effects of metyrosine on ischemia-reperfusion-induced oxidative ovarian injury in rats: Biochemical and histopathological assessment. An Acad Bras Cienc. 2023; 95(2):e20201586.
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Mahdi WA, AlGhamdi SA, Alghamdi AM, Imam SS, Alshehri S, Almaniea MA, Hajjar BM, Al-Abbasi FA, Sayyed N, Kazmi I. Neuroprotectant Effects of Hibiscetin in 3-Nitropropionic Acid-Induced Huntington's Disease via Subsiding Oxidative Stress and Modulating Monoamine Neurotransmitters in Rats Brain. Molecules. 2023 Feb 01; 28(3).
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Elsawy H, Alzahrani AM, Alfwuaires M, Abdel-Moneim AM, Khalil M. Beneficial role of naringin against methotrexate-induced injury to rat testes: biochemical and ultrastructural analyses. Redox Rep. 2022 Dec; 27(1):158-166.
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Fouda AY, Ahmed HA, Pillai B, Kozak A, Hardigan T, Ergul A, Fagan SC, Ishrat T. Contralesional angiotensin type 2 receptor activation contributes to recovery in experimental stroke. Neurochem Int. 2022 09; 158:105375.
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McGill MR, Findley DL, Mazur A, Yee EU, Allard FD, Powers A, Coward L, Blough ER, Gorman G, Hambuchen MD. Radiation Effects on Methamphetamine Pharmacokinetics and Pharmacodynamics in Rats. Eur J Drug Metab Pharmacokinet. 2022 May; 47(3):319-330.
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Ozer M, Ince S, Gundogdu B, Aktas M, Uzel K, Gursul C, Suleyman H, Suleyman Z. Effect of thiamine pyrophosphate on cyclophosphamide-induced oxidative ovarian damage and reproductive dysfunction in female rats. Adv Clin Exp Med. 2022 Feb; 31(2):129-137.
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Alshehri S, Al-Abbasi FA, Ghoneim MM, Imam SS, Afzal M, Alharbi KS, Nadeem MS, Sayyed N, Kazmi I. Anti-Huntington's Effect of Butin in 3-Nitropropionic Acid-Treated Rats: Possible Mechanism of Action. Neurotox Res. 2022 Feb; 40(1):66-77.
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Ayers-Ringler J, McDonald JS, Connors MA, Fisher CR, Han S, Jakaitis DR, Scherer B, Tutor G, Wininger KM, Dai D, Choi DS, Salisbury JL, Jannetto PJ, Bornhorst JA, Kadirvel R, Kallmes DF, McDonald RJ. Neurologic Effects of Gadolinium Retention in the Brain after Gadolinium-based Contrast Agent Administration. Radiology. 2022 03; 302(3):676-683.
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Silva M, Kato Y, Melo MB, Phung I, Freeman BL, Li Z, Roh K, Van Wijnbergen JW, Watkins H, Enemuo CA, Hartwell BL, Chang JYH, Xiao S, Rodrigues KA, Cirelli KM, Li N, Haupt S, Aung A, Cossette B, Abraham W, Kataria S, Bastidas R, Bhiman J, Linde C, Bloom NI, Groschel B, Georgeson E, Phelps N, Thomas A, Bals J, Carnathan DG, Lingwood D, Burton DR, Alter G, Padera TP, Belcher AM, Schief WR, Silvestri G, Ruprecht RM, Crotty S, Irvine DJ. A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity. Sci Immunol. 2021 Dec 03; 6(66):eabf1152.
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Alshehri S, Imam SS. Rosinidin Attenuates Lipopolysaccharide-Induced Memory Impairment in Rats: Possible Mechanisms of Action Include Antioxidant and Anti-Inflammatory Effects. Biomolecules. 2021 11 23; 11(12).
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Ikram H, Tasneem S, Perveen S, Zakir R, Jabeen Haleem D. Neurochemical and behavioral effects of fluoxetine on midazolam induce dependence in an animal model of addiction. Pak J Pharm Sci. 2021 Sep; 34(5):1749-1757.
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Adeneye AA, Olorundare OE, Omobowale TO, Akinsola AO, Kolo PM, Albrecht RMA, Crooks PA. Selected Antihypertensive Agents and Their Fixed-Dose Combinations Effectively Ameliorate Trastuzumab-Mediated Cardiac Dysfunction In Rats. Niger J Physiol Sci. 2021 Jun 30; 36(1):57-65.
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Elsawy H, Alzahrani AM, Alfwuaires M, Sedky A, El-Trass EE, Mahmoud O, Abdel-Moneim AM, Khalil M. Analysis of silymarin-modulating effects against acrylamide-induced cerebellar damage in male rats: Biochemical and pathological markers. J Chem Neuroanat. 2021 09; 115:101964.
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Bagchi AK, Malik A, Akolkar G, Zimmer A, Bell?-Klein A, De Angelis K, Jassal DS, Fini MA, Stenmark KR, Singal PK. Study of ER stress and apoptotic proteins in the heart and tumor exposed to doxorubicin. Biochim Biophys Acta Mol Cell Res. 2021 06; 1868(7):119039.
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de Conti A, Tryndyak V, Heidor R, Jimenez L, Moreno FS, Beland FA, Rusyn I, Pogribny IP. Butyrate-containing structured lipids inhibit RAC1 and epithelial-to-mesenchymal transition markers: a chemopreventive mechanism against hepatocarcinogenesis. J Nutr Biochem. 2020 12; 86:108496.
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Li M, Griffin LE, Corbin S, Neilson AP, Ferruzzi MG. Modulating Phenolic Bioaccessibility and Glycemic Response of Starch-Based Foods in Wistar Rats by Physical Complexation between Starch and Phenolic Acid. J Agric Food Chem. 2020 Nov 18; 68(46):13257-13266.
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Vazquez JH, Clemens MM, Allard FD, Yee EU, Kennon-McGill S, Mackintosh SG, Jaeschke H, Hambuchen MD, McGill MR. Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations. Toxicol Sci. 2020 02 01; 173(2):244-254.
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Hacimuftuoglu A, Mohammadzadeh M, Taghizadehghalehjoughi A, Taspinar N, Togar B, Nalci KA, Okkay U, Gundogdu B. The analgesic effect of metformin on paclitaxel-induced neuropathic pain model in rats: By considering pathological results. J Cancer Res Ther. 2020 Jan-Mar; 16(1):34-39.
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Reyes-Pardo H, Bautista R, Vargas-Robles H, Rios A, S?nchez D, Escalante B. Role of sodium/glucose cotransporter inhibition on a rat model of angiotensin II-dependent kidney damage. BMC Nephrol. 2019 08 02; 20(1):292.
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Cuevas E, Rosas-Hernandez H, Burks SM, Ramirez-Lee MA, Guzman A, Imam SZ, Ali SF, Sarkar S. Amyloid Beta 25-35 induces blood-brain barrier disruption in vitro. Metab Brain Dis. 2019 10; 34(5):1365-1374.
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Eldahshan W, Ishrat T, Pillai B, Sayed MA, Alwhaibi A, Fouda AY, Ergul A, Fagan SC. Angiotensin II type 2 receptor stimulation with compound 21 improves neurological function after stroke in female rats: a pilot study. Am J Physiol Heart Circ Physiol. 2019 05 01; 316(5):H1192-H1201.
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Dibo P, Mara??n RO, Chandrashekar K, Mazzuferi F, Silva GB, Juncos LA, Juncos LI. Angiotensin-(1-7) inhibits sodium transport via Mas receptor by increasing nitric oxide production in thick ascending limb. Physiol Rep. 2019 03; 7(5):e14015.
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Dworatzek E, Mahmoodzadeh S, Schriever C, Kusumoto K, Kramer L, Santos G, Fliegner D, Leung YK, Ho SM, Zimmermann WH, Lutz S, Regitz-Zagrosek V. Sex-specific regulation of collagen I and III expression by 17?-Estradiol in cardiac fibroblasts: role of estrogen receptors. Cardiovasc Res. 2019 02 01; 115(2):315-327.
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Hambuchen MD, Berquist MD, Simecka CM, McGill MR, Gunnell MG, Hendrickson HP, Owens SM. Effect of Bile Duct Ligation-induced Liver Dysfunction on Methamphetamine Pharmacokinetics and Locomotor Activity in Rats. J Pharm Pharm Sci. 2019; 22(1):301-312.
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Ishrat T, Fouda AY, Pillai B, Eldahshan W, Ahmed H, Waller JL, Ergul A, Fagan SC. Dose-response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke. J Cereb Blood Flow Metab. 2019 08; 39(8):1635-1647.
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Robicsek O, Ene HM, Karry R, Ytzhaki O, Asor E, McPhie D, Cohen BM, Ben-Yehuda R, Weiner I, Ben-Shachar D. Isolated Mitochondria Transfer Improves Neuronal Differentiation of Schizophrenia-Derived Induced Pluripotent Stem Cells and Rescues Deficits in a Rat Model of the Disorder. Schizophr Bull. 2018 02 15; 44(2):432-442.
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Interlandi V, Fontanetti PA, Ponce RH, Gallar? RV, Centeno VA. Chronic Exposure to Fluoride During Gestation and Lactation Increases Mandibular Bone Volume of Suckling Rats. Biol Trace Elem Res. 2018 Oct; 185(2):395-403.
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Gong Z, Tasset I, Diaz A, Anguiano J, Tas E, Cui L, Kuliawat R, Liu H, K?hn B, Cuervo AM, Muzumdar R. Humanin is an endogenous activator of chaperone-mediated autophagy. J Cell Biol. 2018 02 05; 217(2):635-647.
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Akolkar G, da Silva Dias D, Ayyappan P, Bagchi AK, Jassal DS, Salemi VMC, Irigoyen MC, De Angelis K, Singal PK. Vitamin C mitigates oxidative/nitrosative stress and inflammation in doxorubicin-induced cardiomyopathy. Am J Physiol Heart Circ Physiol. 2017 Oct 01; 313(4):H795-H809.
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Burgeiro A, Cerqueira MG, Varela-Rodr?guez BM, Nunes S, Neto P, Pereira FC, Reis F, Carvalho E. Glucose and Lipid Dysmetabolism in a Rat Model of Prediabetes Induced by a High-Sucrose Diet. Nutrients. 2017 Jun 21; 9(6).
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Kang YJ, Tian G, Bazrafkan A, Farahabadi MH, Azadian M, Abbasi H, Shamaoun BE, Steward O, Akbari Y. Recovery from Coma Post-Cardiac Arrest Is Dependent on the Orexin Pathway. J Neurotrauma. 2017 10 01; 34(19):2823-2832.
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Scanlon DP, Bah A, Krzeminski M, Zhang W, Leduc-Pessah HL, Dong YN, Forman-Kay JD, Salter MW. An evolutionary switch in ND2 enables Src kinase regulation of NMDA receptors. Nat Commun. 2017 05 16; 8:15220.
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Chanet A, Salles J, Guillet C, Giraudet C, Berry A, Patrac V, Domingues-Faria C, Tagliaferri C, Bouton K, Bertrand-Michel J, Van Dijk M, Jourdan M, Luiking Y, Verlaan S, Pouyet C, Denis P, Boirie Y, Walrand S. Vitamin D supplementation restores the blunted muscle protein synthesis response in deficient old rats through an impact on ectopic fat deposition. J Nutr Biochem. 2017 08; 46:30-38.
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Schmitt VH, Mamilos A, Schmitt C, Neitzer-Planck CNE, Rajab TK, Hollemann D, Wagner W, Kr?mer B, Hierlemann H, James Kirkpatrick C, Brochhausen C. Tissue response to five commercially available peritoneal adhesion barriers-A systematic histological evaluation. J Biomed Mater Res B Appl Biomater. 2018 02; 106(2):598-609.
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Fouda AY, Pillai B, Dhandapani KM, Ergul A, Fagan SC. Role of interleukin-10 in the neuroprotective effect of the Angiotensin Type 2 Receptor agonist, compound 21, after ischemia/reperfusion injury. Eur J Pharmacol. 2017 Mar 15; 799:128-134.
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Cippitelli A, Domi E, Ubaldi M, Douglas JC, Li HW, Demopulos G, Gaitanaris G, Roberto M, Drew PD, Kane CJM, Ciccocioppo R. Protection against alcohol-induced neuronal and cognitive damage by the PPAR? receptor agonist pioglitazone. Brain Behav Immun. 2017 Aug; 64:320-329.
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Brochhausen C, Schmitt VH, Mamilos A, Schmitt C, Planck CN, Rajab TK, Hierlemann H, Kirkpatrick CJ. Expression of CD68 positive macrophages in the use of different barrier materials to prevent peritoneal adhesions-an animal study. J Mater Sci Mater Med. 2017 Jan; 28(1):15.
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Cruz NF, Dienel GA, Patrick PA, Cooper AJL. Organ Distribution of 13N Following Intravenous Injection of [13N]Ammonia into Portacaval-Shunted Rats. Neurochem Res. 2017 Jun; 42(6):1683-1696.
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Garc?a-Casarrubios E, de Moura C, Arroba AI, Pescador N, Calderon-Dominguez M, Garcia L, Herrero L, Serra D, Cadenas S, Reis F, Carvalho E, Obregon MJ, Valverde ?M. Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes. Biochim Biophys Acta. 2016 12; 1861(12 Pt A):1929-1941.
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Pinheiro BS, Lemos C, Neutzling Kaufmann F, Marques JM, da Silva-Santos CS, Carvalho E, Mackie K, Rodrigues RJ, Cunha RA, K?falvi A. Hierarchical glucocorticoid-endocannabinoid interplay regulates the activation of the nucleus accumbens by insulin. Brain Res Bull. 2016 06; 124:222-30.
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Ortega JF, de Conti A, Tryndyak V, Furtado KS, Heidor R, Horst MA, Fernandes LH, Tavares PE, Pogribna M, Shpyleva S, Beland FA, Pogribny IP, Moreno FS. Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein. Oncotarget. 2016 Apr 26; 7(17):24339-47.
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Armstrong C, Wang J, Yeun Lee S, Broderick J, Bezaire MJ, Lee SH, Soltesz I. Target-selectivity of parvalbumin-positive interneurons in layer II of medial entorhinal cortex in normal and epileptic animals. Hippocampus. 2016 06; 26(6):779-93.
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Fouda AY, Alhusban A, Ishrat T, Pillai B, Eldahshan W, Waller JL, Ergul A, Fagan SC. Brain-Derived Neurotrophic Factor Knockdown Blocks the Angiogenic and Protective Effects of Angiotensin Modulation After Experimental Stroke. Mol Neurobiol. 2017 01; 54(1):661-670.
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Heidor R, de Conti A, Ortega JF, Furtado KS, Silva RC, Tavares PE, Purgatto E, Ract JN, de Paiva SA, Gioielli LA, Pogribny IP, Moreno FS. The chemopreventive activity of butyrate-containing structured lipids in experimental rat hepatocarcinogenesis. Mol Nutr Food Res. 2016 Feb; 60(2):420-9.
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Fang XQ, Qiao H, Groveman BR, Feng S, Pflueger M, Xin WK, Ali MK, Lin SX, Xu J, Duclot F, Kabbaj M, Wang W, Ding XS, Santiago-Sim T, Jiang XH, Salter MW, Yu XM. Regulated internalization of NMDA receptors drives PKD1-mediated suppression of the activity of residual cell-surface NMDA receptors. Mol Brain. 2015 Nov 19; 8(1):75.
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Liu CC, Su LJ, Tsai WY, Sun HL, Lee HC, Wong CS. Hylan G-F 20 attenuates posttraumatic osteoarthritis progression: Association with upregulated expression of the circardian gene NPAS2. Life Sci. 2015 Nov 15; 141:20-4.
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Dan H, Zhang L, Qin X, Peng X, Wong M, Tan X, Yu S, Fang N. Moutan cortex extract exerts protective effects in a rat model of cardiac ischemia/reperfusion. Can J Physiol Pharmacol. 2016 Mar; 94(3):245-50.
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