Valproic Acid
"Valproic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fatty acid with anticonvulsant properties used in the treatment of epilepsy. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of voltage dependent sodium channels.
Descriptor ID |
D014635
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MeSH Number(s) |
D02.241.081.944.509.900 D10.251.400.895.593.900
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Concept/Terms |
Valproic Acid- Valproic Acid
- Acid, Valproic
- Propylisopropylacetic Acid
- Acid, Propylisopropylacetic
- 2-Propylpentanoic Acid
- 2 Propylpentanoic Acid
- Divalproex
Sodium Valproate- Sodium Valproate
- Valproate, Sodium
- Valproate Sodium
- Sodium, Valproate
Divalproex Sodium- Divalproex Sodium
- Sodium, Divalproex
- Valproic Acid, Sodium Salt (2:1)
- Semisodium Valproate
- Valproate, Semisodium
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Below are MeSH descriptors whose meaning is more general than "Valproic Acid".
Below are MeSH descriptors whose meaning is more specific than "Valproic Acid".
This graph shows the total number of publications written about "Valproic Acid" by people in UAMS Profiles by year, and whether "Valproic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2024 | 1 | 0 | 1 | 2022 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 | 2020 | 0 | 1 | 1 | 2017 | 2 | 1 | 3 | 2015 | 0 | 1 | 1 | 2012 | 2 | 1 | 3 | 2010 | 1 | 0 | 1 | 2009 | 1 | 0 | 1 | 2008 | 1 | 0 | 1 | 2007 | 0 | 1 | 1 | 2006 | 2 | 0 | 2 | 2005 | 2 | 0 | 2 | 2004 | 2 | 1 | 3 | 2003 | 2 | 0 | 2 | 2002 | 1 | 0 | 1 | 2000 | 0 | 1 | 1 | 1994 | 1 | 0 | 1 | 1993 | 0 | 1 | 1 | 1992 | 2 | 0 | 2 | 1990 | 1 | 0 | 1 |
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Below are the most recent publications written about "Valproic Acid" by people in Profiles over the past ten years.
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Garey JD, Damkier P, Scialli AR, Lusskin S, Braddock SR, Chouchana L, Cleary B, Conover EA, Diav-Citrin O, Dragovich RS, Garcia-Bournissen F, Hodson K, Kennedy D, Lamm SH, Lavigne SA, Obican SG, Panchaud A, Perrotta K, Romeo AN, Shechtman S, Weber-Schoendorfer C. Paternal Valproate Treatment and Risk of Childhood Neurodevelopmental Disorders: Precautionary Regulatory Measures Are Insufficiently Substantiated. Birth Defects Res. 2024 Aug; 116(8):e2392.
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Samanta D. Pharmacotherapeutic management of seizures in patients with Angleman Syndrome. Expert Opin Pharmacother. 2022 Sep; 23(13):1511-1522.
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Kopel J, Grooms A, Ganapathy V, Clothier J. Metformin, valproic acid, and starvation induce seizures in a patient with partial SLC13A5 deficiency: a case of pharmaco-synergistic heterozygosity. Psychiatr Genet. 2021 02 01; 31(1):32-35.
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Samanta D. Epilepsy in Angelman syndrome: A scoping review. Brain Dev. 2021 Jan; 43(1):32-44.
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Yeo QM, Wiley TL, Smith MN, Hammond DA. Oral Agents for the Management of Agitation and Agitated Delirium in Critically Ill Patients. Crit Care Nurs Q. 2017 Oct/Dec; 40(4):344-362.
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Kim D, Garza LA. The Negative Regulator CXXC5: Making WNT Look a Little Less?Dishevelled. J Invest Dermatol. 2017 11; 137(11):2248-2250.
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Almario EE, Borlak J, Suzuki A, Chen M. Drug-Induced Liver Injury. Biomed Res Int. 2017; 2017:2461694.
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Suzuki A, Yuen NA, Ilic K, Miller RT, Reese MJ, Brown HR, Ambroso JI, Falls JG, Hunt CM. Comedications alter drug-induced liver injury reporting frequency: Data mining in the WHO VigiBase?. Regul Toxicol Pharmacol. 2015 Aug; 72(3):481-90.
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