 Diabetes Mellitus, Experimental
"Diabetes Mellitus, Experimental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.
| Descriptor ID |
D003921
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| MeSH Number(s) |
C18.452.394.750.074 C19.246.240 E05.598.500.374
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| Concept/Terms |
Streptozotocin Diabetes- Streptozotocin Diabetes
- Diabetes, Streptozotocin
- Streptozocin Diabetes
- Diabete, Streptozocin
- Diabetes, Streptozocin
- Streptozocin Diabete
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Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Experimental".
Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Experimental".
This graph shows the total number of publications written about "Diabetes Mellitus, Experimental" by people in UAMS Profiles by year, and whether "Diabetes Mellitus, Experimental" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2024 | 1 | 1 | 2 | | 2023 | 4 | 0 | 4 | | 2022 | 3 | 1 | 4 | | 2021 | 6 | 1 | 7 | | 2020 | 2 | 0 | 2 | | 2019 | 5 | 0 | 5 | | 2018 | 3 | 1 | 4 | | 2017 | 3 | 1 | 4 | | 2016 | 3 | 2 | 5 | | 2015 | 2 | 3 | 5 | | 2014 | 3 | 0 | 3 | | 2013 | 3 | 0 | 3 | | 2012 | 1 | 0 | 1 | | 2011 | 3 | 1 | 4 | | 2010 | 3 | 1 | 4 | | 2009 | 1 | 1 | 2 | | 2007 | 1 | 0 | 1 | | 2006 | 0 | 2 | 2 | | 2005 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2003 | 3 | 1 | 4 | | 2002 | 2 | 1 | 3 | | 1999 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1992 | 2 | 0 | 2 | | 1991 | 2 | 0 | 2 | | 1989 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diabetes Mellitus, Experimental" by people in Profiles over the past ten years.
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Racine KC, Iglesias-Carres L, Herring JA, Wieland KL, Ellsworth PN, Tessem JS, Ferruzzi MG, Kay CD, Neilson AP. The high-fat diet and low-dose streptozotocin type-2 diabetes model induces hyperinsulinemia and insulin resistance in male but not female C57BL/6J mice. Nutr Res. 2024 Nov; 131:135-146.
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Turkkahraman H, Flanagan S, Zhu T, Akel N, Marino S, Ortega-Gonzalez D, Yuan X, Bellido T. Sclerostin antibody corrects periodontal disease in type 2 diabetic mice. JCI Insight. 2024 Jul 18; 9(16).
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El-Baz YG, Moustafa A, Ali MA, El-Desoky GE, Wabaidur SM, Iqbal A. Green synthesized silver nanoparticles for the treatment of diabetes and the related complications of hyperlipidemia and oxidative stress in diabetic rats. Exp Biol Med (Maywood). 2023 Dec; 248(23):2237-2248.
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Pinho ACO, Santos D, Oliveira PJ, Leal EC, Carvalho E. Real-time OXPHOS capacity analysis in wounded skin from diabetic mice: A pilot study. Eur J Clin Invest. 2024 Mar; 54(3):e14128.
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Blanco T, Musayeva A, Singh RB, Nakagawa H, Lee S, Alemi H, Gonzalez-Nolasco B, Ortiz G, Wang S, Kahale F, Dohlman TH, Chen Y, Dana R. The impact of donor diabetes on corneal transplant immunity. Am J Transplant. 2023 09; 23(9):1345-1358.
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Leal EC, Emanuelli T, Santos D, Moura J, Catarina Rg Fonseca A, Burgeiro A, Carvalho E. Dysregulation of endoplasmic reticulum stress response in skin wounds in a streptozotocin-induced diabetes mouse model. J Mol Endocrinol. 2023 04 01; 70(3).
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Yuan X, Amin V, Zhu T, Kittaka M, Ueki Y, Bellido TM, Turkkahraman H. Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling. J Periodontol. 2023 02; 94(2):277-289.
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Pinho ACO, Santos D, Baldeiras I, Burgeiro A, Leal EC, Carvalho E. Mitochondrial respiration in thoracic perivascular adipose tissue of diabetic mice. J Endocrinol. 2022 09 01; 254(3):169-184.
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Fouda AY, Ahmed HA, Pillai B, Kozak A, Hardigan T, Ergul A, Fagan SC, Ishrat T. Contralesional angiotensin type 2 receptor activation contributes to recovery in experimental stroke. Neurochem Int. 2022 09; 158:105375.
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Reyes-Pardo H, S?nchez-Herrera DP, Santill?n M. On the effects of diabetes mellitus on the mechanical properties of DRG sensory neurons and their possible relation with diabetic neuropathy. Phys Biol. 2022 05 10; 19(4).
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Petersen C, Bharat D, Wankhade UD, Kim JS, Cutler BR, Denetso C, Gholami S, Nelson S, Bigley J, Johnson A, Chintapalli SV, Piccolo BD, Satheesh Babu AK, Paz HA, Shankar K, Symons JD, Anandh Babu PV. Dietary Blueberry Ameliorates Vascular Complications in Diabetic Mice Possibly through NOX4 and Modulates Composition and Functional Diversity of Gut Microbes. Mol Nutr Food Res. 2022 04; 66(8):e2100784.
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Afzal M, Al-Abbasi FA, Kazmi I, Imam SS, Alshehri S, Ghoneim MM, Almalki WH, Nadeem MS, Sayyed N. Fustin Inhibits Oxidative Free Radicals and Inflammatory Cytokines in Cerebral Cortex and Hippocampus and Protects Cognitive Impairment in Streptozotocin-Induced Diabetic Rats. ACS Chem Neurosci. 2021 12 15; 12(24):4587-4597.
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Widiapradja A, Kasparian AO, McCaffrey SL, Kolb LL, Imig JD, Lacey JL, Melendez GC, Levick SP. Replacement of Lost Substance P Reduces Fibrosis in the Diabetic Heart by Preventing Adverse Fibroblast and Macrophage Phenotype Changes. Cells. 2021 10 05; 10(10).
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Matsuzaki S, Eyster C, Newhardt MF, Giorgione JR, Kinter C, Young ZT, Kinter M, Humphries KM. Insulin signaling alters antioxidant capacity in the diabetic heart. Redox Biol. 2021 11; 47:102140.
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Leal EC, Moura LIF, Pirzgalska RM, Marques-da-Silva D, Ledent C, K?falvi A, Carvalho E. Diabetes and Cannabinoid CB1 receptor deficiency promote similar early onset aging-like changes in the skin. Exp Gerontol. 2021 10 15; 154:111528.
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Khan MAH, Hwang SH, Barnett SD, Stavniichuk A, Jankiewicz WK, Hammock BD, Imig JD. Multitarget molecule, PTUPB, to treat diabetic nephropathy in rats. Br J Pharmacol. 2021 11; 178(22):4468-4484.
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Wang Y, Niu A, Pan Y, Cao S, Terker AS, Wang S, Fan X, Toth CL, Ramirez Solano MA, Michell DL, Contreras D, Allen RM, Zhu W, Sheng Q, Fogo AB, Vickers KC, Zhang MZ, Harris RC. Profile of Podocyte Translatome During Development of Type 2 and Type 1 Diabetic Nephropathy Using Podocyte-Specific TRAP mRNA RNA-seq. Diabetes. 2021 10; 70(10):2377-2390.
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Sultan HK, El-Ayat WM, AbouGhalia AH, Lasheen NN, Moustafa AS. Study of long non-coding RNA and mitochondrial dysfunction in diabetic rats. Tissue Cell. 2021 Aug; 71:101516.
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Song KM, Kim WJ, Choi MJ, Kwon KD, Limanjaya A, Ghatak K, Ock J, Yin GN, Sato Y, Hong SS, Ryu JK, Suh JK. Vasohibin-1 rescues erectile function through up-regulation of angiogenic factors in the diabetic mice. Sci Rep. 2021 01 13; 11(1):1114.
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Sharma S, Plotkin M. Id1 expression in kidney endothelial cells protects against diabetes-induced microvascular injury. FEBS Open Bio. 2020 08; 10(8):1447-1462.
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Song KM, Kim WJ, Choi MJ, Limanjaya A, Ghatak K, Minh NN, Ock J, Yin GN, Hong SS, Suh JK, Ryu JK. Intracavernous delivery of Dickkopf3 gene or peptide rescues erectile function through enhanced cavernous angiogenesis in the diabetic mouse. Andrology. 2020 09; 8(5):1387-1397.
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Kwon MH, Song KM, Limanjaya A, Choi MJ, Ghatak K, Nguyen NM, Ock J, Yin GN, Kang JH, Lee MR, Gho YS, Ryu JK, Suh JK. Embryonic stem cell-derived extracellular vesicle-mimetic nanovesicles rescue erectile function by enhancing penile neurovascular regeneration in the streptozotocin-induced diabetic mouse. Sci Rep. 2019 12 27; 9(1):20072.
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Choubey M, Ranjan A, Bora PS, Krishna A. Protective role of adiponectin against testicular impairment in high-fat diet/streptozotocin-induced type 2 diabetic mice. Biochimie. 2020 Jan; 168:41-52.
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Nguyen NM, Song KM, Choi MJ, Ghatak K, Kwon MH, Ock J, Yin GN, Ryu JK, Suh JK. Inhibition of proNGF and p75NTR Pathway Restores Erectile Function Through Dual Angiogenic and Neurotrophic Effects in the Diabetic Mouse. J Sex Med. 2019 03; 16(3):351-364.
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Petersen C, Wankhade UD, Bharat D, Wong K, Mueller JE, Chintapalli SV, Piccolo BD, Jalili T, Jia Z, Symons JD, Shankar K, Anandh Babu PV. Dietary supplementation with strawberry induces marked changes in the composition and functional potential of the gut microbiome in diabetic mice. J Nutr Biochem. 2019 04; 66:63-69.
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Silva C, Sampaio-Pinto V, Andrade S, Rodrigues I, Costa R, Guerreiro S, Carvalho E, Pinto-do-? P, Nascimento DS, Soares R. Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse Model. Cell Physiol Biochem. 2019; 52(3):503-516.
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Miller BS, Blumenthal SR, Shalygin A, Wright KD, Staruschenko A, Imig JD, Sorokin A. Inactivation of p66Shc Decreases Afferent Arteriolar KATP Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats. Diabetes. 2018 11; 67(11):2206-2212.
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Hye Khan MA, Kolb L, Skibba M, Hartmann M, Bl?cher R, Proschak E, Imig JD. A novel dual PPAR-? agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes. Diabetologia. 2018 10; 61(10):2235-2246.
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Shosha E, Xu Z, Narayanan SP, Lemtalsi T, Fouda AY, Rojas M, Xing J, Fulton D, Caldwell RW, Caldwell RB. Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1. Int J Mol Sci. 2018 Apr 17; 19(4).
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Yadlapalli JSK, Dogra N, Walbaum AW, Prather PL, Crooks PA, Dobretsov M. Pinprick hypo- and hyperalgesia in diabetic rats: Can diet content affect experimental outcome? Neurosci Lett. 2018 04 23; 673:24-27.
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Bockus LB, Matsuzaki S, Vadvalkar SS, Young ZT, Giorgione JR, Newhardt MF, Kinter M, Humphries KM. Cardiac Insulin Signaling Regulates Glycolysis Through Phosphofructokinase 2 Content and Activity. J Am Heart Assoc. 2017 Dec 04; 6(12).
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Yadlapalli JSK, Dogra N, Walbaum AW, Prather PL, Crooks PA, Dobretsov M. Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy. Life Sci. 2018 Jan 01; 192:151-159.
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Bhatta A, Yao L, Xu Z, Toque HA, Chen J, Atawia RT, Fouda AY, Bagi Z, Lucas R, Caldwell RB, Caldwell RW. Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1. Cardiovasc Res. 2017 Nov 01; 113(13):1664-1676.
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Chen TY, Ferruzzi MG, Wu QL, Simon JE, Talcott ST, Wang J, Ho L, Todd G, Cooper B, Pasinetti GM, Janle EM. Influence of diabetes on plasma pharmacokinetics and brain bioavailability of grape polyphenols and their phase II metabolites in the Zucker diabetic fatty rat. Mol Nutr Food Res. 2017 10; 61(10).
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Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG. Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia. Biochim Biophys Acta Gen Subj. 2017 Nov; 1861(11 Pt A):2758-2765.
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Asakura M, Fukami T, Nakajima M, Fujii H, Atsuda K, Itoh T, Fujiwara R. Hepatic Dipeptidyl Peptidase-4 Controls Pharmacokinetics of Vildagliptin In Vivo. Drug Metab Dispos. 2017 02; 45(2):237-245.
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Das ND, Yin GN, Choi MJ, Song KM, Park JM, Limanjaya A, Ghatak K, Minh NN, Ock J, Park SH, Kim HM, Ryu JK, Suh JK. Effectiveness of Intracavernous Delivery of Recombinant Human Hepatocyte Growth Factor on Erectile Function in the Streptozotocin-Induced Diabetic Mouse. J Sex Med. 2016 11; 13(11):1618-1628.
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Maycas M, McAndrews KA, Sato AY, Pellegrini GG, Brown DM, Allen MR, Plotkin LI, Gortazar AR, Esbrit P, Bellido T. PTHrP-Derived Peptides Restore Bone Mass and Strength in Diabetic Mice: Additive Effect of Mechanical Loading. J Bone Miner Res. 2017 Mar; 32(3):486-497.
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Yadlapalli JSK, Ford BM, Ketkar A, Wan A, Penthala NR, Eoff RL, Prather PL, Dobretsov M, Crooks PA. Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors. Pharmacol Res. 2016 11; 113(Pt A):335-347.
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Iyer S, Han L, Ambrogini E, Yavropoulou M, Fowlkes J, Manolagas SC, Almeida M. Deletion of FoxO1, 3, and 4 in Osteoblast Progenitors Attenuates the Loss of Cancellous Bone Mass in a Mouse Model of Type 1 Diabetes. J Bone Miner Res. 2017 01; 32(1):60-69.
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Tellechea A, Leal EC, Kafanas A, Auster ME, Kuchibhotla S, Ostrovsky Y, Tecilazich F, Baltzis D, Zheng Y, Carvalho E, Zabolotny JM, Weng Z, Petra A, Patel A, Panagiotidou S, Pradhan-Nabzdyk L, Theoharides TC, Veves A. Mast Cells Regulate Wound Healing in Diabetes. Diabetes. 2016 07; 65(7):2006-19.
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Thrailkill KM, Clay Bunn R, Nyman JS, Rettiganti MR, Cockrell GE, Wahl EC, Uppuganti S, Lumpkin CK, Fowlkes JL. SGLT2 inhibitor therapy improves blood glucose but does not prevent diabetic bone disease in diabetic DBA/2J male mice. Bone. 2016 Jan; 82:101-7.
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Yin GN, Das ND, Choi MJ, Song KM, Kwon MH, Ock J, Limanjaya A, Ghatak K, Kim WJ, Hyun JS, Koh GY, Ryu JK, Suh JK. The pericyte as a cellular regulator of penile erection and a novel therapeutic target for erectile dysfunction. Sci Rep. 2015 Jun 05; 5:10891.
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Subathra M, Korrapati M, Howell LA, Arthur JM, Shayman JA, Schnellmann RG, Siskind LJ. Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells. Am J Physiol Renal Physiol. 2015 Aug 01; 309(3):F204-15.
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Leal EC, Carvalho E, Tellechea A, Kafanas A, Tecilazich F, Kearney C, Kuchibhotla S, Auster ME, Kokkotou E, Mooney DJ, LoGerfo FW, Pradhan-Nabzdyk L, Veves A. Substance P promotes wound healing in diabetes by modulating inflammation and macrophage phenotype. Am J Pathol. 2015 Jun; 185(6):1638-48.
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Song KM, Choi MJ, Kwon MH, Ghatak K, Park SH, Ryu DS, Ryu JK, Suh JK. Optimizing in vivo gene transfer into mouse corpus cavernosum by use of surface electroporation. Korean J Urol. 2015 Mar; 56(3):197-204.
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