Insulysin
"Insulysin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme the catalyzes the degradation of insulin, glucagon and other polypeptides. It is inhibited by bacitracin, chelating agents EDTA and 1,10-phenanthroline, and by thiol-blocking reagents such as N-ethylmaleimide, but not phosphoramidon. (Eur J Biochem 1994;223:1-5) EC 3.4.24.56.
| Descriptor ID |
D007339
|
| MeSH Number(s) |
D08.811.277.656.300.480.300 D08.811.277.656.675.374.300
|
| Concept/Terms |
Insulysin- Insulysin
- Insulin-Degrading Enzyme
- Enzyme, Insulin-Degrading
- Insulin Degrading Enzyme
- Insulin Protease
- Protease, Insulin
- Insulin Proteinase
- Proteinase, Insulin
- Insulinase
|
Below are MeSH descriptors whose meaning is more general than "Insulysin".
Below are MeSH descriptors whose meaning is more specific than "Insulysin".
This graph shows the total number of publications written about "Insulysin" by people in UAMS Profiles by year, and whether "Insulysin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Insulysin" by people in Profiles over the past ten years.
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Kulas JA, Franklin WF, Smith NA, Manocha GD, Puig KL, Nagamoto-Combs K, Hendrix RD, Taglialatela G, Barger SW, Combs CK. Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues. Am J Physiol Endocrinol Metab. 2019 01 01; 316(1):E106-E120.