Glutamate Decarboxylase
"Glutamate Decarboxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining GAMMA-AMINOBUTYRIC ACID levels in normal nervous tissues. The brain enzyme also acts on L-cysteate, L-cysteine sulfinate, and L-aspartate. EC 4.1.1.15.
| Descriptor ID |
D005968
|
| MeSH Number(s) |
D08.811.520.224.125.250
|
| Concept/Terms |
Glutamate Decarboxylase- Glutamate Decarboxylase
- Decarboxylase, Glutamate
- Glutamic Acid Decarboxylase
- Acid Decarboxylase, Glutamic
- Decarboxylase, Glutamic Acid
- Glutamate Carboxy-Lyase
- Carboxy-Lyase, Glutamate
- Glutamate Carboxy Lyase
|
Below are MeSH descriptors whose meaning is more general than "Glutamate Decarboxylase".
Below are MeSH descriptors whose meaning is more specific than "Glutamate Decarboxylase".
This graph shows the total number of publications written about "Glutamate Decarboxylase" by people in UAMS Profiles by year, and whether "Glutamate Decarboxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glutamate Decarboxylase" by people in Profiles over the past ten years.
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Wei M, Bannout F, Dastjerdi M, Phan C, Batarseh S, Guo X, Baker N. Immunotherapy in a case of low titre GAD65 antibody-associated spectrum neurological disorders. BMJ Case Rep. 2024 Jun 13; 17(6).