 Insulin-Like Growth Factor I
"Insulin-Like Growth Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
| Descriptor ID |
D007334
|
| MeSH Number(s) |
D12.644.276.937.400 D12.776.124.862.400 D12.776.467.937.400 D23.529.937.400
|
| Concept/Terms |
Insulin-Like Growth Factor I- Insulin-Like Growth Factor I
- Insulin-Like Somatomedin Peptide I
- Insulin Like Somatomedin Peptide I
- Somatomedin C
- IGF-I-SmC
- IGF-1
- IGF-I
- Insulin Like Growth Factor I
|
Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor I".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor I".
This graph shows the total number of publications written about "Insulin-Like Growth Factor I" by people in UAMS Profiles by year, and whether "Insulin-Like Growth Factor I" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 2 | 2 | | 2022 | 2 | 1 | 3 | | 2021 | 2 | 0 | 2 | | 2020 | 2 | 0 | 2 | | 2019 | 0 | 3 | 3 | | 2018 | 1 | 0 | 1 | | 2017 | 1 | 2 | 3 | | 2016 | 4 | 1 | 5 | | 2015 | 0 | 1 | 1 | | 2013 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2009 | 2 | 2 | 4 | | 2008 | 0 | 2 | 2 | | 2007 | 2 | 5 | 7 | | 2006 | 3 | 3 | 6 | | 2005 | 2 | 2 | 4 | | 2004 | 0 | 1 | 1 | | 2003 | 3 | 1 | 4 | | 2002 | 3 | 5 | 8 | | 2001 | 1 | 1 | 2 | | 2000 | 1 | 0 | 1 | | 1999 | 1 | 3 | 4 | | 1998 | 1 | 0 | 1 | | 1997 | 2 | 1 | 3 | | 1996 | 0 | 3 | 3 | | 1995 | 2 | 1 | 3 | | 1993 | 0 | 1 | 1 | | 1992 | 0 | 2 | 2 | | 1990 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Insulin-Like Growth Factor I" by people in Profiles over the past ten years.
-
Smith DL, Mitchell SE, Johnson MS, Gibbs VK, Dickinson S, Henschel B, Li R, Kaiser KA, Chusyd DE, Brown AW, Allison DB, Speakman JR, Nagy TR. Benefits of calorie restriction in mice are mediated via energy imbalance, not absolute energy or protein intake. Geroscience. 2024 Oct; 46(5):4809-4826.
-
Tenshin H, Delgado-Calle J, Windle JJ, Roodman GD, Chirgwin JM, Kurihara N. Osteocytes and Paget's Disease of Bone. Curr Osteoporos Rep. 2024 04; 22(2):266-272.
-
Pantet O, Viana MV, Engelen MPKJ, Deutz NEP, Gran S, Berger MM. Impact of ?-hydroxy-?-methylbutyrate (HMB) in critically ill patients on the endocrine axis - A post-hoc cohort study of the HMB-ICU trial. Clin Nutr ESPEN. 2023 02; 53:1-6.
-
Mitchell R, Chacko J. Clinical and Mechanistic Review of Amiodarone-Associated Optic Neuropathy. Biomolecules. 2022 09 14; 12(9).
-
Androschuk AM, Tam TH, Mahou R, Lo C, Salter MW, Sefton MV. Methacrylic acid-based biomaterials promote peripheral innervation in the subcutaneous space of mice. Biomaterials. 2022 10; 289:121764.
-
Hritzo B, Aghdam SY, Legesse B, Kaur A, Cao M, Boerma M, Chakraborty N, Dimitrov G, Gautam A, Hammamieh R, Wilkins W, Tsioplaya A, Holmes-Hampton GP, Moroni M. Late Health Effects of Partial Body Irradiation Injury in a Minipig Model Are Associated with Changes in Systemic and Cardiac IGF-1 Signaling. Int J Mol Sci. 2021 Mar 23; 22(6).
-
Castillo-Castrejon M, Yang IV, Davidson EJ, Borengasser SJ, Jambal P, Westcott J, Kemp JF, Garces A, Ali SA, Saleem S, Goldenberg RL, Figueroa L, Hambidge KM, Krebs NF, Powell TL. Preconceptional Lipid-Based Nutrient Supplementation in 2 Low-Resource Countries Results in Distinctly Different IGF-1/mTOR Placental Responses. J Nutr. 2021 03 11; 151(3):556-569.
-
Amiri M, Raeisi-Dehkordi H, Vorland CJ, Chen X, Brown AW, Allison DB. Double-counting of effect sizes and inappropriate exclusion of studies in "The influence of vitamin D supplementation on IGF-1 levels in humans: A systematic review and meta-analysis". Ageing Res Rev. 2021 03; 66:101236.
-
Miyagawa K, Ohata Y, Delgado-Calle J, Teramachi J, Zhou H, Dempster DD, Subler MA, Windle JJ, Chirgwin JM, Roodman GD, Kurihara N. Osteoclast-derived IGF1 is required for pagetic lesion formation in vivo. JCI Insight. 2020 03 26; 5(6).
-
Diaz EC, Cleves MA, DiCarlo M, Sobik SR, Ruebel ML, Thakali KM, Sims CR, Dajani NK, Krukowski RA, B?rsheim E, Badger TM, Shankar K, Andres A. Parental adiposity differentially associates with newborn body composition. Pediatr Obes. 2020 04; 15(4):e12596.
-
Voinsky I, Bennuri SC, Svigals J, Frye RE, Rose S, Gurwitz D. Peripheral Blood Mononuclear Cell Oxytocin and Vasopressin Receptor Expression Positively Correlates with Social and Behavioral Function in Children with Autism. Sci Rep. 2019 09 17; 9(1):13443.
-
Wong HK, Hoermann R, Grossmann M. Reversible male hypogonadotropic hypogonadism due to energy deficit. Clin Endocrinol (Oxf). 2019 07; 91(1):3-9.
-
Kaur A, Ten Have GAM, Hritzo B, Deutz NEP, Olsen C, Moroni M. Morphological and functional impairment in the gut in a partial body irradiation minipig model of GI-ARS. Int J Radiat Biol. 2020 01; 96(1):112-128.
-
Kenchegowda D, Legesse B, Hritzo B, Olsen C, Aghdam S, Kaur A, Culp W, Derrien-Colemyn A, Severson G, Moroni M. Selective Insulin-like Growth Factor Resistance Associated with Heart Hemorrhages and Poor Prognosis in a Novel Preclinical Model of the Hematopoietic Acute Radiation Syndrome. Radiat Res. 2018 08; 190(2):164-175.
-
Dennis RA, Garner KK, Kortebein PM, Parkes CM, Bopp MM, Li S, Padala KP, Padala PR, Sullivan DH. Single-Arm Resistance Training Study to Determine the Relationship between Training Outcomes and Muscle Growth Factor mRNAs in Older Adults Consuming Numerous Medications and Supplements. J Nutr Health Aging. 2018; 22(2):269-275.
-
Carmichael JD, Broder MS, Cherepanov D, Chang E, Mamelak A, Said Q, Neary MP, Bonert V. Long-term treatment outcomes of acromegaly patients presenting biochemically-uncontrolled at a tertiary pituitary center. BMC Endocr Disord. 2017 Aug 04; 17(1):49.
-
Raisingani M, Preneet B, Kohn B, Yakar S. Skeletal growth and bone mineral acquisition in type 1 diabetic children; abnormalities of the GH/IGF-1 axis. Growth Horm IGF Res. 2017 06; 34:13-21.
-
DeBoer MD, Vijayakumar V, Gong M, Fowlkes JL, Smith RM, Ruiz-Perez F, Nataro JP. Mice with infectious colitis exhibit linear growth failure and subsequent catch-up growth related to systemic inflammation and IGF-1. Nutr Res. 2017 Mar; 39:34-42.
-
Redd MJ, Hoffman JR, Gepner Y, Stout JR, Hoffman MW, Ben-Dov D, Funk S, Church DD, Avital G, Chen Y, Frankel H, Ostfeld I. The effect of HMB ingestion on the IGF-I and IGF binding protein response to high intensity military training. Growth Horm IGF Res. 2017 02; 32:55-59.
-
Tarantini S, Tucsek Z, Valcarcel-Ares MN, Toth P, Gautam T, Giles CB, Ballabh P, Wei JY, Wren JD, Ashpole NM, Sonntag WE, Ungvari Z, Csiszar A. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289.
-
Tarantini S, Giles CB, Wren JD, Ashpole NM, Valcarcel-Ares MN, Wei JY, Sonntag WE, Ungvari Z, Csiszar A. IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis. Age (Dordr). 2016 Aug; 38(4):239-258.
-
Smith SS, Dole NS, Franceschetti T, Hrdlicka HC, Delany AM. MicroRNA-433 Dampens Glucocorticoid Receptor Signaling, Impacting Circadian Rhythm and Osteoblastic Gene Expression. J Biol Chem. 2016 Oct 07; 291(41):21717-21728.
-
Church DD, Schwarz NA, Spillane MB, McKinley-Barnard SK, Andre TL, Ramirez AJ, Willoughby DS. l-Leucine Increases Skeletal Muscle IGF-1 but Does Not Differentially Increase Akt/mTORC1 Signaling and Serum IGF-1 Compared to Ursolic Acid in Response to Resistance Exercise in Resistance-Trained Men. J Am Coll Nutr. 2016 Sep-Oct; 35(7):627-638.
-
Gonzalez AM, Hoffman JR, Jajtner AR, Townsend JR, Boone CH, Beyer KS, Baker KM, Wells AJ, Church DD, Mangine GT, Oliveira LP, Moon JR, Fukuda DH, Stout JR. Protein supplementation does not alter intramuscular anabolic signaling or endocrine response after resistance exercise in trained men. Nutr Res. 2015 Nov; 35(11):990-1000.
-
Sinha S, Shukla S, Khan S, Tollefsbol TO, Meeran SM. Epigenetic reactivation of p21CIP1/WAF1 and KLOTHO by a combination of bioactive dietary supplements is partially ERa-dependent in ERa-negative human breast cancer cells. Mol Cell Endocrinol. 2015 May 05; 406:102-14.
-
Hutchison MR, White PC. Prostacyclin regulates bone growth via the Epac/Rap1 pathway. Endocrinology. 2015 Feb; 156(2):499-510.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|