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Uroporphyrinogen Decarboxylase

"Uroporphyrinogen Decarboxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA.


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This graph shows the total number of publications written about "Uroporphyrinogen Decarboxylase" by people in UAMS Profiles by year, and whether "Uroporphyrinogen Decarboxylase" was a major or minor topic of these publications.
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