Hypertrophy
"Hypertrophy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
Descriptor ID |
D006984
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MeSH Number(s) |
C23.300.775
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hypertrophy".
Below are MeSH descriptors whose meaning is more specific than "Hypertrophy".
This graph shows the total number of publications written about "Hypertrophy" by people in UAMS Profiles by year, and whether "Hypertrophy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2024 | 0 | 2 | 2 | 2023 | 0 | 1 | 1 | 2022 | 0 | 2 | 2 | 2021 | 0 | 1 | 1 | 2020 | 1 | 6 | 7 | 2019 | 1 | 4 | 5 | 2018 | 0 | 2 | 2 | 2017 | 1 | 1 | 2 | 2016 | 0 | 3 | 3 | 2015 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2011 | 1 | 1 | 2 | 2009 | 0 | 2 | 2 | 2007 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2003 | 0 | 3 | 3 | 2001 | 0 | 1 | 1 | 1999 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 1995 | 0 | 1 | 1 | 1991 | 0 | 1 | 1 | 1989 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Hypertrophy" by people in Profiles over the past ten years.
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Qin X, Liu P, Jin L, Zhu K, Yang Y, Hou Z, Zhang H, Zheng Q. Exerkine ?-aminoisobutyric acid protects against atrial structural remodeling and atrial fibrillation in obesity via activating AMPK signaling and improving insulin sensitivity. Biomed Pharmacother. 2024 Feb; 171:116137.
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Goorani S, Khan AH, Mishra A, El-Meanawy A, Imig JD. Kidney Injury by Unilateral Ureteral Obstruction in Mice Lacks Sex Differences. Kidney Blood Press Res. 2024; 49(1):69-80.
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Nolt GL, Keeble AR, Wen Y, Strong AC, Thomas NT, Valentino TR, Brightwell CR, Murach KA, Patrizia S, Weinstabl H, Gollner A, McCarthy JJ, Fry CS, Franti M, Filareto A, Peterson CA, Dungan CM. Inhibition of p53-MDM2 binding reduces senescent cell abundance and improves the adaptive responses of skeletal muscle from aged mice. Geroscience. 2024 04; 46(2):2153-2176.
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Ayesh Haj Yousef MH, Al-Khatib SM, Khasawneh RA, Rahabneh L. Subcutaneous panniculitis-like T-cell lymphoma: an unusual cause of right thigh hypertrophy. BMJ Case Rep. 2022 Dec 02; 15(12).
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Long DE, Peck BD, Lavin KM, Dungan CM, Kosmac K, Tuggle SC, Bamman MM, Kern PA, Peterson CA. Skeletal muscle properties show collagen organization and immune cell content are associated with resistance exercise response heterogeneity in older persons. J Appl Physiol (1985). 2022 06 01; 132(6):1432-1447.
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Figueiredo VC, Wen Y, Alkner B, Fernandez-Gonzalo R, Norrbom J, Vechetti IJ, Valentino T, Mobley CB, Zentner GE, Peterson CA, McCarthy JJ, Murach KA, von Walden F. Genetic and epigenetic regulation of skeletal muscle ribosome biogenesis with exercise. J Physiol. 2021 07; 599(13):3363-3384.
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Pham AK, Miller M, Rosenthal P, Das S, Weng N, Jang S, Kurten RC, Badrani J, Doherty TA, Oliver B, Broide DH. ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility. JCI Insight. 2021 04 08; 6(7).
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Englund DA, Figueiredo VC, Dungan CM, Murach KA, Peck BD, Petrosino JM, Brightwell CR, Dupont AM, Neal AC, Fry CS, Accornero F, McCarthy JJ, Peterson CA. Satellite Cell Depletion Disrupts Transcriptional Coordination and Muscle Adaptation to Exercise. Function (Oxf). 2021; 2(1):zqaa033.
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Mayhew AC, Bost J, Linam L, Milla S, Farahzad M, Childress KJ. Compensatory Ovarian Hypertrophy after Unilateral Oophorectomy: Evaluation of Ovarian Volumes in Pediatric and Adolescent Populations. J Pediatr Adolesc Gynecol. 2020 Dec; 33(6):631-638.
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Murach KA, McCarthy JJ, Peterson CA, Dungan CM. Making Mice Mighty: recent advances in translational models of load-induced muscle hypertrophy. J Appl Physiol (1985). 2020 09 01; 129(3):516-521.
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Murach KA, Vechetti IJ, Van Pelt DW, Crow SE, Dungan CM, Figueiredo VC, Kosmac K, Fu X, Richards CI, Fry CS, McCarthy JJ, Peterson CA. Fusion-Independent Satellite Cell Communication to Muscle Fibers During Load-Induced Hypertrophy. Function (Oxf). 2020; 1(1):zqaa009.
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Von Walden F, Rea M, Mobley CB, Fondufe-Mittendorf Y, McCarthy JJ, Peterson CA, Murach KA. The myonuclear DNA methylome in response to an acute hypertrophic stimulus. Epigenetics. 2020 11; 15(11):1151-1162.
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Englund DA, Murach KA, Dungan CM, Figueiredo VC, Vechetti IJ, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Depletion of resident muscle stem cells negatively impacts running volume, physical function, and muscle fiber hypertrophy in response to lifelong physical activity. Am J Physiol Cell Physiol. 2020 06 01; 318(6):C1178-C1188.
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Riedl JC, Musayeva A, Wasielica-Poslednik J, Weyer-Elberich V, Pfeiffer N, Gericke A. Analysis of the Corneal Anterior and Posterior Surface in Patients With Peripheral Hypertrophic Subepithelial Corneal Opacification. Eye Contact Lens. 2020 Mar; 46(2):105-109.
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Figueiredo VC, Englund DA, Vechetti IJ, Alimov A, Peterson CA, McCarthy JJ. Phosphorylation of eukaryotic initiation factor 4E is dispensable for skeletal muscle hypertrophy. Am J Physiol Cell Physiol. 2019 12 01; 317(6):C1247-C1255.
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Murach KA, Dungan CM, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. "Muscle memory" not mediated by myonuclear number? Secondary analysis of human detraining data. J Appl Physiol (1985). 2019 12 01; 127(6):1814-1816.
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Moro T, Brightwell CR, Phalen DE, McKenna CF, Lane SJ, Porter C, Volpi E, Rasmussen BB, Fry CS. Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults. Exp Gerontol. 2019 11; 127:110723.
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Englund DA, Peck BD, Murach KA, Neal AC, Caldwell HA, McCarthy JJ, Peterson CA, Dupont-Versteegden EE. Resident muscle stem cells are not required for testosterone-induced skeletal muscle hypertrophy. Am J Physiol Cell Physiol. 2019 10 01; 317(4):C719-C724.
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Dungan CM, Murach KA, Frick KK, Jones SR, Crow SE, Englund DA, Vechetti IJ, Figueiredo VC, Levitan BM, Satin J, McCarthy JJ, Peterson CA. Elevated myonuclear density during skeletal muscle hypertrophy in response to training is reversed during detraining. Am J Physiol Cell Physiol. 2019 05 01; 316(5):C649-C654.
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Gupta K, Jadhav R, Ali A, Virmani S. What is this image? 2018: Image?4 result : PET-CT appearance of benign lipomatous hypertrophy of inter-atrial septum. J Nucl Cardiol. 2019 Feb; 26(1):31-33.
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Murach KA, Fry CS, Kirby TJ, Jackson JR, Lee JD, White SH, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Starring or Supporting Role? Satellite Cells and Skeletal Muscle Fiber Size Regulation. Physiology (Bethesda). 2018 Jan 01; 33(1):26-38.
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Stuart CA, Lee ML, South MA, Howell MEA, Stone MH. Muscle hypertrophy in prediabetic men after 16 wk of resistance training. J Appl Physiol (1985). 2017 Oct 01; 123(4):894-901.
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Walker G, Limaye K, Jankowitz BT, Jadhav AP. Hypertrophic olivary degeneration after cerebellar hemorrhage. J Clin Neurosci. 2017 Sep; 43:162-164.
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Fry CS, Kirby TJ, Kosmac K, McCarthy JJ, Peterson CA. Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy. Cell Stem Cell. 2017 01 05; 20(1):56-69.
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Faden H, Callanan V, Pizzuto M, Nagy M, Wilby M, Lamson D, Wrotniak B, Juretschko S, St George K. The ubiquity of asymptomatic respiratory viral infections in the tonsils and adenoids of children and their impact on airway obstruction. Int J Pediatr Otorhinolaryngol. 2016 Nov; 90:128-132.
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Kirby TJ, Patel RM, McClintock TS, Dupont-Versteegden EE, Peterson CA, McCarthy JJ. Myonuclear transcription is responsive to mechanical load and DNA content but uncoupled from cell size during hypertrophy. Mol Biol Cell. 2016 Mar 01; 27(5):788-98.
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Tkachenko E, Rawson R, La E, Doherty TA, Baum R, Cavagnero K, Miyanohara A, Dohil R, Kurten RC, Aceves SS. Rigid substrate induces esophageal smooth muscle hypertrophy and eosinophilic esophagitis fibrotic gene expression. J Allergy Clin Immunol. 2016 Apr; 137(4):1270-1272.e1.
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Lee JD, Fry CS, Mula J, Kirby TJ, Jackson JR, Liu F, Yang L, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Aged Muscle Demonstrates Fiber-Type Adaptations in Response to Mechanical Overload, in the Absence of Myofiber Hypertrophy, Independent of Satellite Cell Abundance. J Gerontol A Biol Sci Med Sci. 2016 Apr; 71(4):461-7.
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