 Electron Transport Complex IV
"Electron Transport Complex IV" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13 different protein subunits. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects electrons that are transferred from the reduced CYTOCHROME C GROUP and donates them to molecular OXYGEN, which is then reduced to water. The redox reaction is simultaneously coupled to the transport of PROTONS across the inner mitochondrial membrane.
| Descriptor ID |
D003576
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| MeSH Number(s) |
D05.500.562.374 D08.811.600.250.687 D08.811.682.285 D12.776.157.530.450.250.875.304 D12.776.543.277.687 D12.776.543.585.450.250.875.484
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| Concept/Terms |
Electron Transport Complex IV- Electron Transport Complex IV
- Ferrocytochrome c Oxygen Oxidoreductase
- Cytochrome-c Oxidase (Complex IV)
- Cytochrome Oxidase
- Oxidase, Cytochrome
- Cytochrome-c Oxidase
- Cytochrome c Oxidase
- Oxidase, Cytochrome-c
Signal Peptide p25-Subunit IV Cytochrome Oxidase- Signal Peptide p25-Subunit IV Cytochrome Oxidase
- Signal Peptide p25 Subunit IV Cytochrome Oxidase
- Pre-CTOX p25
- p25 Presequence Peptide-Cytochrome Oxidase
- p25 Presequence Peptide Cytochrome Oxidase
Cytochrome aa3- Cytochrome aa3
- Heme aa3 Cytochrome Oxidase
- Cytochrome a,a3
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Below are MeSH descriptors whose meaning is more general than "Electron Transport Complex IV".
Below are MeSH descriptors whose meaning is more specific than "Electron Transport Complex IV".
This graph shows the total number of publications written about "Electron Transport Complex IV" by people in UAMS Profiles by year, and whether "Electron Transport Complex IV" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2018 | 1 | 1 | 2 | | 2017 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2014 | 0 | 3 | 3 | | 2013 | 1 | 1 | 2 | | 2012 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2010 | 1 | 4 | 5 | | 2009 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2004 | 1 | 1 | 2 | | 2002 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 |
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Below are the most recent publications written about "Electron Transport Complex IV" by people in Profiles over the past ten years.
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Blackburn ML, Wankhade UD, Ono-Moore KD, Chintapalli SV, Fox R, Rutkowsky JM, Willis BJ, Tolentino T, Lloyd KCK, Adams SH. On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice. Am J Physiol Endocrinol Metab. 2021 07 01; 321(1):E47-E62.
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McDermott MM, Criqui MH, Domanchuk K, Ferrucci L, Guralnik JM, Kibbe MR, Kosmac K, Kramer CM, Leeuwenburgh C, Li L, Lloyd-Jones D, Peterson CA, Polonsky TS, Stein JH, Sufit R, Van Horn L, Villarreal F, Zhang D, Zhao L, Tian L. Cocoa to Improve Walking Performance in Older People With Peripheral Artery Disease: The COCOA-PAD Pilot Randomized Clinical Trial. Circ Res. 2020 02 28; 126(5):589-599.
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Samanta D, Gokden M. PEHO syndrome: KIF1A mutation and decreased activity of mitochondrial respiratory chain complex. J Clin Neurosci. 2019 Mar; 61:298-301.
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Nowak G, Bakajsova-Takacsova D. Protein kinase Ce targets respiratory chain and mitochondrial membrane potential but not F0 F1 -ATPase in renal cells injured by oxidant. J Cell Biochem. 2018 11; 119(11):9394-9407.
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Rocha MC, Rosa HS, Grady JP, Blakely EL, He L, Romain N, Haller RG, Newman J, McFarland R, Ng YS, Gorman GS, Schaefer AM, Tuppen HA, Taylor RW, Turnbull DM. Pathological mechanisms underlying single large-scale mitochondrial DNA deletions. Ann Neurol. 2018 01; 83(1):115-130.
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Delhey L, Kilinc EN, Yin L, Slattery J, Tippett M, Wynne R, Rose S, Kahler S, Damle S, Legido A, Goldenthal MJ, Frye RE. Bioenergetic variation is related to autism symptomatology. Metab Brain Dis. 2017 12; 32(6):2021-2031.
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Hartman JH, Miller GP, Caro AA, Byrum SD, Orr LM, Mackintosh SG, Tackett AJ, MacMillan-Crow LA, Hallberg LM, Ameredes BT, Boysen G. 1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice. Toxicology. 2017 03 01; 378:114-124.
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Nowak G, Takacsova-Bakajsova D, Megyesi J. Deletion of protein kinase C-e attenuates mitochondrial dysfunction and ameliorates ischemic renal injury. Am J Physiol Renal Physiol. 2017 01 01; 312(1):F109-F120.
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Lax NZ, Alston CL, Schon K, Park SM, Krishnakumar D, He L, Falkous G, Ogilvy-Stuart A, Lees C, King RH, Hargreaves IP, Brown GK, McFarland R, Dean AF, Taylor RW. Neuropathologic Characterization of Pontocerebellar Hypoplasia Type 6 Associated With Cardiomyopathy and Hydrops Fetalis and Severe Multisystem Respiratory Chain Deficiency due to Novel RARS2 Mutations. J Neuropathol Exp Neurol. 2015 Jul; 74(7):688-703.
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Yarham JW, Lamichhane TN, Pyle A, Mattijssen S, Baruffini E, Bruni F, Donnini C, Vassilev A, He L, Blakely EL, Griffin H, Santibanez-Koref M, Bindoff LA, Ferrero I, Chinnery PF, McFarland R, Maraia RJ, Taylor RW. Defective i6A37 modification of mitochondrial and cytosolic tRNAs results from pathogenic mutations in TRIT1 and its substrate tRNA. PLoS Genet. 2014 Jun; 10(6):e1004424.
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Gr?newald A, Lax NZ, Rocha MC, Reeve AK, Hepplewhite PD, Rygiel KA, Taylor RW, Turnbull DM. Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue. J Neurosci Methods. 2014 Jul 30; 232:143-9.
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