Pyruvate Dehydrogenase Complex
"Pyruvate Dehydrogenase Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multienzyme complex responsible for the formation of ACETYL COENZYME A from pyruvate. The enzyme components are PYRUVATE DEHYDROGENASE (LIPOAMIDE); dihydrolipoamide acetyltransferase; and LIPOAMIDE DEHYDROGENASE. Pyruvate dehydrogenase complex is subject to three types of control: inhibited by acetyl-CoA and NADH; influenced by the energy state of the cell; and inhibited when a specific serine residue in the pyruvate decarboxylase is phosphorylated by ATP. PYRUVATE DEHYDROGENASE (LIPOAMIDE)-PHOSPHATASE catalyzes reactivation of the complex. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Descriptor ID |
D011768
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MeSH Number(s) |
D05.500.562.625 D08.811.600.741
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Concept/Terms |
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This graph shows the total number of publications written about "Pyruvate Dehydrogenase Complex" by people in UAMS Profiles by year, and whether "Pyruvate Dehydrogenase Complex" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2012 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyruvate Dehydrogenase Complex" by people in Profiles over the past ten years.