Lin-Xi Li
Title | Associate Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Microbiology & Immunology, College of Medicine |
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Division | Microbiology & Immunology Faculty |
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Address | 325 S. Elm St. Mail Slot # 511 Little Rock AR 72205
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Phone | 501-686-6949 |
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ORCID
| 0000-0002-5526-8966 |
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vCard | Download vCard |
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Research 1R21AI180670-01A1 (LI, LIN-XI)May 10, 2024 - Mar 31, 2026 NIH/Nat. Inst. of Allergy & Infectious Diseases Exploring early protective immune responses to Chlamydia Role: Principal Investigator |
| 5R21AI180670-02 (LI, LIN-XI)May 10, 2024 - Mar 31, 2026 NIH/Nat. Inst. of Allergy & Infectious Diseases Exploring early protective immune responses to Chlamydia Role: Principal Investigator |
| 2R01HL146713 (MU, SHENGYU)Apr 10, 2024 - Mar 31, 2029 NIH/Nat. Heart, Lung & Blood Institute T cell homing to the kidney contributes to salt retention and blood pressure regulation - Continuation Role: Co-Investigator |
| R01AI139124 (LI, LIN-XI)May 18, 2018 - Apr 30, 2024 NIH/Nat. Inst. of Allergy & Infectious Diseases Mechanisms of memory CD4 T cell-mediated immune protection against Chlamydia - Continuation Role: Principal Investigator |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Andrews JT, Zhang Z, Prasad GVRK, Huey F, Nazarova EV, Wang J, Ranaraja A, Weinkopff T, Li LX, Mu S, Birrer MJ, Huang SC, Zhang N, Arg?ello RJ, Philips JA, Mattila JT, Huang L. Metabolically active neutrophils represent a permissive niche for Mycobacterium tuberculosis. Mucosal Immunol. 2024 Jun 04. PMID: 38844208.
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Mercado MAB, Li Q, Quick CM, Kim Y, Palmer R, Huang L, Li LX. BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against Chlamydia. PLoS Pathog. 2024 Jan; 20(1):e1011983. PMID: 38271477.
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Benson LN, Deck KS, Mora CJ, Guo Y, Rafferty TM, Li LX, Huang L, Andrews JT, Qin Z, Trott DW, Hoover RS, Liu Y, Mu S. P2X7-Mediated Antigen-Independent Activation of CD8+ T Cells Promotes Salt-Sensitive Hypertension. Hypertension. 2024 Mar; 81(3):530-540. PMID: 38193292.
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Mercado MAB, Li Q, Quick CM, Kim Y, Palmer R, Huang L, Li LX. BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against Chlamydia. bioRxiv. 2023 Nov 05. PMID: 37961221.
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Gann JI, Malaviarachchi PA, Du W, Mercado MAB, Li LX. IFN? and Antibody Synergize To Enhance Protective Immunity against Chlamydia Dissemination and Female Reproductive Tract Reinfections. Infect Immun. 2022 12 15; 90(12):e0032822. PMID: 36374101.
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Benson LN, Liu Y, Wang X, Xiong Y, Rhee SW, Guo Y, Deck KS, Mora CJ, Li LX, Huang L, Andrews JT, Qin Z, Hoover RS, Ko B, Williams RM, Heller DA, Jaimes EA, Mu S. The IFN?-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension. Circ Res. 2022 05 13; 130(10):1550-1564. PMID: 35430873.
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Alhallak I, Wolter KG, Castro Munoz A, Simmen FA, Ward RJ, Petty SA, Li LX, Simmen RCM. Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10. J Mol Endocrinol. 2021 09 09; 67(4):173-188. PMID: 34382943.
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Mercado MAB, Du W, Malaviarachchi PA, Gann JI, Li LX. Innate IFN-? Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-? Production Is Highly Redundant in the Female Reproductive Tract. Infect Immun. 2021 02 16; 89(3). PMID: 33257535.
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Malaviarachchi PA, Mercado MAB, McSorley SJ, Li LX. Antibody, but not B-cell-dependent antigen presentation, plays an essential role in preventing Chlamydia systemic dissemination in mice. Eur J Immunol. 2020 05; 50(5):676-684. PMID: 32026472.
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Li LX, Labuda JC, Imai DM, Griffey SM, McSorley SJ. CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract. J Immunol. 2017 10 01; 199(7):2547-2554. PMID: 28801359.
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Jiang J, Liu G, Kickhoefer VA, Rome LH, Li LX, McSorley SJ, Kelly KA. A Protective Vaccine against Chlamydia Genital Infection Using Vault Nanoparticles without an Added Adjuvant. Vaccines (Basel). 2017 Jan 19; 5(1). PMID: 28106821.
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Li LX, Benoun JM, Weiskopf K, Garcia KC, McSorley SJ. Salmonella Infection Enhances Erythropoietin Production by the Kidney and Liver, Which Correlates with Elevated Bacterial Burdens. Infect Immun. 2016 10; 84(10):2833-41. PMID: 27456828.
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Qualai J, Cantero J, Li LX, Carrascosa JM, Cabr? E, Dern O, Sumoy L, Requena G, McSorley SJ, Genesc? M. Adhesion Molecules Associated with Female Genital Tract Infection. PLoS One. 2016; 11(6):e0156605. PMID: 27272720.
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Qualai J, Li LX, Cantero J, Tarrats A, Fern?ndez MA, Sumoy L, Rodolosse A, McSorley SJ, Genesc? M. Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential. PLoS One. 2016; 11(4):e0154253. PMID: 27119555.
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Li LX, McSorley SJ. A re-evaluation of the role of B cells in protective immunity to Chlamydia infection. Immunol Lett. 2015 Apr; 164(2):88-93. PMID: 25704502.
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Atif SM, Lee SJ, Li LX, Uematsu S, Akira S, Gorjestani S, Lin X, Schweighoffer E, Tybulewicz VL, McSorley SJ. Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9. Eur J Immunol. 2015 Feb; 45(2):513-24. PMID: 25430631.
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O'Donnell H, Pham OH, Li LX, Atif SM, Lee SJ, Ravesloot MM, Stolfi JL, Nuccio SP, Broz P, Monack DM, Baumler AJ, McSorley SJ. Toll-like receptor and inflammasome signals converge to amplify the innate bactericidal capacity of T helper 1 cells. Immunity. 2014 Feb 20; 40(2):213-24. PMID: 24508233.
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Li LX, McSorley SJ. B cells enhance antigen-specific CD4 T cell priming and prevent bacteria dissemination following Chlamydia muridarum genital tract infection. PLoS Pathog. 2013 Oct; 9(10):e1003707. PMID: 24204262.
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Li LX, Atif SM, Schmiel SE, Lee SJ, McSorley SJ. Increased susceptibility to Salmonella infection in signal regulatory protein a-deficient mice. J Immunol. 2012 Sep 01; 189(5):2537-44. PMID: 22851710.
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Griffin AJ, Li LX, Voedisch S, Pabst O, McSorley SJ. Dissemination of persistent intestinal bacteria via the mesenteric lymph nodes causes typhoid relapse. Infect Immun. 2011 Apr; 79(4):1479-88. PMID: 21263018.
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Vang KB, Yang J, Pag?n AJ, Li LX, Wang J, Green JM, Beg AA, Farrar MA. Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development. J Immunol. 2010 Apr 15; 184(8):4074-7. PMID: 20228198.
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Li LX, Goetz CA, Katerndahl CD, Sakaguchi N, Farrar MA. A Flt3- and Ras-dependent pathway primes B cell development by inducing a state of IL-7 responsiveness. J Immunol. 2010 Feb 15; 184(4):1728-36. PMID: 20065110.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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2010 | 2 | 2011 | 1 | 2012 | 1 | 2013 | 1 | 2014 | 2 | 2015 | 1 | 2016 | 3 | 2017 | 2 | 2020 | 1 | 2021 | 2 | 2022 | 2 | 2023 | 1 | 2024 | 3 |
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