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Lin-Xi Li

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentMicrobiology & Immunology, College of Medicine
DivisionMicrobiology & Immunology Faculty
Address325 S. Elm St.
Mail Slot # 511
Little Rock AR 72205
Phone501-686-6949
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    Collapse Research 
    Collapse research activities and funding
    R01AI139124     (LI, LIN-XI)May 18, 2018 - Apr 30, 2023
    NIH/Nat. Inst. of Allergy & Infectious Diseases
    Mechanisms of memory CD4 T cell-mediated immune protection against Chlamydia
    Role: Principal Investigator
    P20GM103625     (SMELTZER, MARK S)Aug 15, 2012 - Apr 30, 2022
    NIH
    Center for Microbial Pathogenesis and Host Inflammatory Responses
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Mercado MAB, Du W, Malaviarachchi PA, Gann JI, Li LX. Innate IFN-? Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-? Production Is Highly Redundant in the Female Reproductive Tract. Infect Immun. 2021 02 16; 89(3). PMID: 33257535.
      View in: PubMed
    2. Malaviarachchi PA, Mercado MAB, McSorley SJ, Li LX. Antibody, but not B-cell-dependent antigen presentation, plays an essential role in preventing Chlamydia systemic dissemination in mice. Eur J Immunol. 2020 05; 50(5):676-684. PMID: 32026472.
      View in: PubMed
    3. Li LX, Labuda JC, Imai DM, Griffey SM, McSorley SJ. CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract. J Immunol. 2017 10 01; 199(7):2547-2554. PMID: 28801359.
      View in: PubMed
    4. Jiang J, Liu G, Kickhoefer VA, Rome LH, Li LX, McSorley SJ, Kelly KA. A Protective Vaccine against Chlamydia Genital Infection Using Vault Nanoparticles without an Added Adjuvant. Vaccines (Basel). 2017 Jan 19; 5(1). PMID: 28106821.
      View in: PubMed
    5. Li LX, Benoun JM, Weiskopf K, Garcia KC, McSorley SJ. Salmonella Infection Enhances Erythropoietin Production by the Kidney and Liver, Which Correlates with Elevated Bacterial Burdens. Infect Immun. 2016 10; 84(10):2833-41. PMID: 27456828.
      View in: PubMed
    6. Qualai J, Cantero J, Li LX, Carrascosa JM, Cabré E, Dern O, Sumoy L, Requena G, McSorley SJ, Genescà M. Adhesion Molecules Associated with Female Genital Tract Infection. PLoS One. 2016; 11(6):e0156605. PMID: 27272720.
      View in: PubMed
    7. Qualai J, Li LX, Cantero J, Tarrats A, Fernández MA, Sumoy L, Rodolosse A, McSorley SJ, Genescà M. Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential. PLoS One. 2016; 11(4):e0154253. PMID: 27119555.
      View in: PubMed
    8. Li LX, McSorley SJ. A re-evaluation of the role of B cells in protective immunity to Chlamydia infection. Immunol Lett. 2015 Apr; 164(2):88-93. PMID: 25704502.
      View in: PubMed
    9. Atif SM, Lee SJ, Li LX, Uematsu S, Akira S, Gorjestani S, Lin X, Schweighoffer E, Tybulewicz VL, McSorley SJ. Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9. Eur J Immunol. 2015 Feb; 45(2):513-24. PMID: 25430631.
      View in: PubMed
    10. O'Donnell H, Pham OH, Li LX, Atif SM, Lee SJ, Ravesloot MM, Stolfi JL, Nuccio SP, Broz P, Monack DM, Baumler AJ, McSorley SJ. Toll-like receptor and inflammasome signals converge to amplify the innate bactericidal capacity of T helper 1 cells. Immunity. 2014 Feb 20; 40(2):213-24. PMID: 24508233.
      View in: PubMed
    11. Li LX, McSorley SJ. B cells enhance antigen-specific CD4 T cell priming and prevent bacteria dissemination following Chlamydia muridarum genital tract infection. PLoS Pathog. 2013 Oct; 9(10):e1003707. PMID: 24204262.
      View in: PubMed
    12. Li LX, Atif SM, Schmiel SE, Lee SJ, McSorley SJ. Increased susceptibility to Salmonella infection in signal regulatory protein a-deficient mice. J Immunol. 2012 Sep 01; 189(5):2537-44. PMID: 22851710.
      View in: PubMed
    13. Griffin AJ, Li LX, Voedisch S, Pabst O, McSorley SJ. Dissemination of persistent intestinal bacteria via the mesenteric lymph nodes causes typhoid relapse. Infect Immun. 2011 Apr; 79(4):1479-88. PMID: 21263018.
      View in: PubMed
    14. Vang KB, Yang J, Pagán AJ, Li LX, Wang J, Green JM, Beg AA, Farrar MA. Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development. J Immunol. 2010 Apr 15; 184(8):4074-7. PMID: 20228198.
      View in: PubMed
    15. Li LX, Goetz CA, Katerndahl CD, Sakaguchi N, Farrar MA. A Flt3- and Ras-dependent pathway primes B cell development by inducing a state of IL-7 responsiveness. J Immunol. 2010 Feb 15; 184(4):1728-36. PMID: 20065110.
      View in: PubMed
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