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Jerry Ware

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPhysiology & Biophysics, College of Medicine
DivisionPhysiology & Biophysics Platelet
Address263-2 Biomedical Research II
200 South Cedar
Mail Slot # 505
Little Rock AR 72202
Phone501-526-6096
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    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Program Coordinator & Associate Director of the Arkansas INBRE

    Chair, Institution Animal Care and Use Committee (IACUC)


    Collapse Educational Activities 
    Collapse teaching overview
    Basic Science Module Director for Hematology/Oncology


    Collapse Research Funds 
    Collapse research activities
    S1017-001-UAM     (WARE, JERRY)Aug 1, 2017 - Feb 28, 2018
    DHHS - Biomedical Advanced Research and Development Authority - Pass Through: Cellphire, Inc.
    Murine Hemostatic Properties of Thrombosomes
    Role: Principal Investigator

    R21AI133160     (WARE, JERRY)May 25, 2017 - Apr 30, 2019
    NIH/NIAID
    Leukocyte-platelet modulation of the systemic inflammatory response
    Role: Principal Investigator

    17GRNT33410609     (POST, STEVEN)Jan 1, 2017 - May 25, 2017
    American Heart Association
    Platelet-leukocyte regulation of inflammatory responses- Resubmission- Resubmission
    Role: Co-Investigator

    P20GM109005     (HAUER-JENSEN, MARTIN)Jun 24, 2015 - Mar 31, 2020
    NIH/NIGMS
    Center for Studies of Host Response to Cancer Therapy
    Role: Co-Investigator

    R21AR061991     (WARE, JERRY)Sep 15, 2011 - Jul 31, 2014
    NIH/NIAMS
    Platelet glycoprotein VI dependent microparticle formation
    Role: Principal Investigator

    W81XWH-08-1-0576     (WARE, JERRY)Sep 1, 2008 - Aug 31, 2011
    US Department of the Army
    Platelet glycoprotein Ib-IX and malignancy
    Role: Principal Investigator

    R01HL069951     (WARE, JERRY)Apr 1, 2002 - Mar 31, 2007
    NIH/NHLBI
    Characterization and Analysis of Platelet Septins
    Role: Principal Investigator

    P20GM103429     (CORNETT, LAWRENCE E)Sep 30, 2001 - Apr 30, 2020
    NIH/NIGMS
    Partnerships for Biomedical Research in Arkansas
    Role: Co-Investigator

    R01HL050545     (WARE, JERRY)May 1, 1994 - May 31, 2014
    NIH/NHLBI
    Transgenic analysis of platelet receptor expression
    Role: Principal Investigator

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    The links below are provided by the researcher to provide access to external online bibliographies that they keep independently from the Profiles System.
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Jain N, Wan F, Kothari M, Adelodun A, Ware J, Sarode R, Hedayati SS. Association of platelet function with depression and its treatment with sertraline in patients with chronic kidney disease: analysis of a randomized trial. BMC Nephrol. 2019 Oct 29; 20(1):395. PMID: 31664940.
      View in: PubMed
    2. Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M. Platelet GPIba is a mediator and potential interventional target for NASH and subsequent liver cancer. Nat Med. 2019 04; 25(4):641-655. PMID: 30936549.
      View in: PubMed
    3. Garg S, Sadhukhan R, Banerjee S, Savenka AV, Basnakian AG, McHargue V, Wang J, Pawar SA, Ghosh SP, Ware J, Hauer-Jensen M, Pathak R. Gamma-Tocotrienol Protects the Intestine from Radiation Potentially by Accelerating Mesenchymal Immune Cell Recovery. Antioxidants (Basel). 2019 Mar 06; 8(3). PMID: 30845647.
      View in: PubMed
    4. Birnie E, Claushuis TAM, Koh GCKW, Limmathurotsakul D, Day NPJ, Roelofs JJTH, Ware J, Hou B, de Vos AF, van der Poll T, van 't Veer C, Wiersinga WJ. Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis). J Infect Dis. 2019 01 29; 219(4):648-659. PMID: 30312422.
      View in: PubMed
    5. Franco AT, Ware J. Pathophysiology 2: The Role of Platelets in Cancer Biology. Cancer Treat Res. 2019; 179:37-54. PMID: 31317479.
      View in: PubMed
    6. Asfari A, Dent JA, Corken A, Herington D, Kaliki V, Sra N, Hefley G, Pasala S, Prodhan P, Ware J. Platelet Glycoprotein VI Haplotypes and the Presentation of Paediatric Sepsis. Thromb Haemost. 2019 Mar; 119(3):431-438. PMID: 30597490.
      View in: PubMed
    7. Corken, A. and Ware J. A dynamic platelet - tumor cell axis. Annals of Blood. 2018; (3):47.
    8. Ware J. Let's shear a moment, then take it inside. Blood. 2018 08 02; 132(5):467-468. PMID: 30072415.
      View in: PubMed
    9. Claushuis TAM, de Stoppelaar SF, de Vos AF, Grootemaat AE, van der Wel NN, Roelofs JJTH, Ware J, Van't Veer C, van der Poll T. Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis. Arterioscler Thromb Vasc Biol. 2018 08; 38(8):1772-1784. PMID: 29930006.
      View in: PubMed
    10. Xu M, Li J, Neves MAD, Zhu G, Carrim N, Yu R, Gupta S, Marshall J, Rotstein O, Peng J, Hou M, Kunishima S, Ware J, Branch DR, Lazarus AH, Ruggeri ZM, Freedman J, Ni H. GPIba is required for platelet-mediated hepatic thrombopoietin generation. Blood. 2018 08 09; 132(6):622-634. PMID: 29794068.
      View in: PubMed
    11. Stark K, Schubert I, Joshi U, Kilani B, Hoseinpour P, Thakur M, Grünauer P, Pfeiler S, Schmidergall T, Stockhausen S, Bäumer M, Chandraratne S, von Brühl ML, Lorenz M, Coletti R, Reese S, Laitinen I, Wörmann SM, Algül H, Bruns CJ, Ware J, Mackman N, Engelmann B, Massberg S. Distinct Pathogenesis of Pancreatic Cancer Microvesicle-Associated Venous Thrombosis Identifies New Antithrombotic Targets In Vivo. Arterioscler Thromb Vasc Biol. 2018 04; 38(4):772-786. PMID: 29419408.
      View in: PubMed
    12. Rayes J, Jadoui S, Lax S, Gros A, Wichaiyo S, Ollivier V, Denis CV, Ware J, Nieswandt B, Jandrot-Perrus M, Watson SP, Ho-Tin-Noé B. The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent. Haematologica. 2018 06; 103(6):e256-e258. PMID: 29419432.
      View in: PubMed
    13. Quach ME, Dragovich MA, Chen W, Syed AK, Cao W, Liang X, Deng W, De Meyer SF, Zhu G, Peng J, Ni H, Bennett CM, Hou M, Ware J, Deckmyn H, Zhang XF, Li R. Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets. Blood. 2018 02 15; 131(7):787-796. PMID: 29203584.
      View in: PubMed
    14. Chen W, Druzak SA, Wang Y, Josephson CD, Hoffmeister KM, Ware J, Li R. Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets. Arterioscler Thromb Vasc Biol. 2017 12; 37(12):2271-2279. PMID: 29097365.
      View in: PubMed
    15. Ware J, Varughese KI. Structural origins of hemostasis and adaptive immunity. Res Pract Thromb Haemost. 2017 Oct; 1(2):286-290. PMID: 30046698.
      View in: PubMed
    16. Dütting S, Gaits-Iacovoni F, Stegner D, Popp M, Antkowiak A, van Eeuwijk JMM, Nurden P, Stritt S, Heib T, Aurbach K, Angay O, Cherpokova D, Heinz N, Baig AA, Gorelashvili MG, Gerner F, Heinze KG, Ware J, Krohne G, Ruggeri ZM, Nurden AT, Schulze H, Modlich U, Pleines I, Brakebusch C, Nieswandt B. A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis. Nat Commun. 2017 06 15; 8:15838. PMID: 28643773.
      View in: PubMed
    17. Cunin P, Penke LR, Thon JN, Monach PA, Jones T, Chang MH, Chen MM, Melki I, Lacroix S, Iwakura Y, Ware J, Gurish MF, Italiano JE, Boilard E, Nigrovic PA. Megakaryocytes compensate for Kit insufficiency in murine arthritis. J Clin Invest. 2017 May 01; 127(5):1714-1724. PMID: 28375155.
      View in: PubMed
    18. Kaur H, Corscadden K, Ware J, Othman M. Thrombocytopathy leading to impaired in vivo haemostasis and thrombosis in platelet type von Willebrand disease. Thromb Haemost. 2017 02 28; 117(3):543-555. PMID: 28004055.
      View in: PubMed
    19. Deng W, Xu Y, Chen W, Paul DS, Syed AK, Dragovich MA, Liang X, Zakas P, Berndt MC, Di Paola J, Ware J, Lanza F, Doering CB, Bergmeier W, Zhang XF, Li R. Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor. Nat Commun. 2016 Sep 27; 7:12863. PMID: 27670775.
      View in: PubMed
    20. Chen W, Liang X, Syed AK, Jessup P, Church WR, Ware J, Josephson CD, Li R. Inhibiting GPIba Shedding Preserves Post-Transfusion Recovery and Hemostatic Function of Platelets After Prolonged Storage. Arterioscler Thromb Vasc Biol. 2016 09; 36(9):1821-8. PMID: 27417583.
      View in: PubMed
    21. Zhou H, Ran Y, Da Q, Shaw TS, Shang D, Reddy AK, López JA, Ballantyne CM, Ware J, Wu H, Peng Y. Defective Association of the Platelet Glycoprotein Ib-IX Complex with the Glycosphingolipid-Enriched Membrane Domain Inhibits Murine Thrombus and Atheroma Formation. J Immunol. 2016 07 01; 197(1):288-95. PMID: 27206768.
      View in: PubMed
    22. Ware J. A binding relationship with thrombin. Blood. 2016 Feb 04; 127(5):525-6. PMID: 26847068.
      View in: PubMed
    23. Liang X, Syed AK, Russell SR, Ware J, Li R. Dimerization of glycoprotein Iba is not sufficient to induce platelet clearance. J Thromb Haemost. 2016 Feb; 14(2):381-6. PMID: 26662889.
      View in: PubMed
    24. Franco AT, Corken A, Ware J. Platelets at the interface of thrombosis, inflammation, and cancer. Blood. 2015 Jul 30; 126(5):582-8. PMID: 26109205.
      View in: PubMed
    25. Nikolic DM, Vadali S, He B, Ware J, Kelly T, Post SR. Prostaglandins produced during class A scavenger receptor-mediated macrophage adhesion differentially regulate cytokine production. J Leukoc Biol. 2015 May; 97(5):901-908. PMID: 25717147.
      View in: PubMed
    26. Chandraratne S, von Bruehl ML, Pagel JI, Stark K, Kleinert E, Konrad I, Farschtschi S, Coletti R, Gärtner F, Chillo O, Legate KR, Lorenz M, Rutkowski S, Caballero-Martinez A, Starke R, Tirniceriu A, Pauleikhoff L, Fischer S, Assmann G, Mueller-Hoecker J, Ware J, Nieswandt B, Schaper W, Schulz C, Deindl E, Massberg S. Critical role of platelet glycoprotein iba in arterial remodeling. Arterioscler Thromb Vasc Biol. 2015 Mar; 35(3):589-97. PMID: 25550202.
      View in: PubMed
    27. Ware J, Post SR. Platelets: balancing the septic triad. Blood. 2014 Dec 11; 124(25):3670-2. PMID: 25498452.
      View in: PubMed
    28. Bynagari-Settipalli YS, Cornelissen I, Palmer D, Duong D, Concengco C, Ware J, Coughlin SR. Redundancy and interaction of thrombin- and collagen-mediated platelet activation in tail bleeding and carotid thrombosis in mice. Arterioscler Thromb Vasc Biol. 2014 Dec; 34(12):2563-9. PMID: 25278288.
      View in: PubMed
    29. Kanaji S, Fahs SA, Ware J, Montgomery RR, Shi Q. Non-myeloablative conditioning with busulfan before hematopoietic stem cell transplantation leads to phenotypic correction of murine Bernard-Soulier syndrome. J Thromb Haemost. 2014 Oct; 12(10):1726-32. PMID: 25066812.
      View in: PubMed
    30. Corken A, Russell S, Dent J, Post SR, Ware J. Platelet glycoprotein Ib-IX as a regulator of systemic inflammation. Arterioscler Thromb Vasc Biol. 2014 May; 34(5):996-1001. PMID: 24504734.
      View in: PubMed
    31. Pokidysheva E, Boudko S, Vranka J, Zientek K, Maddox K, Moser M, Fässler R, Ware J, Bächinger HP. Biological role of prolyl 3-hydroxylation in type IV collagen. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):161-6. PMID: 24368846.
      View in: PubMed
    32. Liang X, Russell SR, Estelle S, Jones LH, Cho S, Kahn ML, Berndt MC, Bunting ST, Ware J, Li R. Specific inhibition of ectodomain shedding of glycoprotein Iba by targeting its juxtamembrane shedding cleavage site. J Thromb Haemost. 2013 Dec; 11(12):2155-62. PMID: 24119228.
      View in: PubMed
    33. Ware J. Thrombocytopathy and type 2B von Willebrand disease. J Clin Invest. 2013 Dec; 123(12):5004-6. PMID: 24270415.
      View in: PubMed
    34. Yin H, Stojanovic-Terpo A, Xu W, Corken A, Zakharov A, Qian F, Pavlovic S, Krbanjevic A, Lyubimov AV, Wang ZJ, Ware J, Du X. Role for platelet glycoprotein Ib-IX and effects of its inhibition in endotoxemia-induced thrombosis, thrombocytopenia, and mortality. Arterioscler Thromb Vasc Biol. 2013 Nov; 33(11):2529-37. PMID: 24051142.
      View in: PubMed
    35. Ware J, Corken A, Khetpal R. Platelet function beyond hemostasis and thrombosis. Curr Opin Hematol. 2013 Sep; 20(5):451-6. PMID: 23839296.
      View in: PubMed
    36. Hillgruber C, Steingräber AK, Pöppelmann B, Denis CV, Ware J, Vestweber D, Nieswandt B, Schneider SW, Goerge T. Blocking von Willebrand factor for treatment of cutaneous inflammation. J Invest Dermatol. 2014 Jan; 134(1):77-86. PMID: 23812299.
      View in: PubMed
    37. Ware J. Give me an intron: any intron. Blood. 2013 May 23; 121(21):4251-2. PMID: 23704045.
      View in: PubMed
    38. Boulaftali Y, Hess PR, Getz TM, Cholka A, Stolla M, Mackman N, Owens AP, Ware J, Kahn ML, Bergmeier W. Platelet ITAM signaling is critical for vascular integrity in inflammation. J Clin Invest. 2013 Feb; 123(2):908-16. PMID: 23348738.
      View in: PubMed
    39. Ware J. Fragmenting the platelet to reduce metastasis. Blood. 2012 Oct 04; 120(14):2779-80. PMID: 23043025.
      View in: PubMed
    40. Joglekar MV, Ware J, Xu J, Fitzgerald ME, Gartner TK. Platelets, glycoprotein Ib-IX, and von Willebrand factor are required for FeCl(3)-induced occlusive thrombus formation in the inferior vena cava of mice. Platelets. 2013; 24(3):205-12. PMID: 22720736.
      View in: PubMed
    41. von Brühl ML, Stark K, Steinhart A, Chandraratne S, Konrad I, Lorenz M, Khandoga A, Tirniceriu A, Coletti R, Köllnberger M, Byrne RA, Laitinen I, Walch A, Brill A, Pfeiler S, Manukyan D, Braun S, Lange P, Riegger J, Ware J, Eckart A, Haidari S, Rudelius M, Schulz C, Echtler K, Brinkmann V, Schwaiger M, Preissner KT, Wagner DD, Mackman N, Engelmann B, Massberg S. Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. J Exp Med. 2012 Apr 09; 209(4):819-35. PMID: 22451716.
      View in: PubMed
    42. Ziu E, Mercado CP, Li Y, Singh P, Ahmed BA, Freyaldenhoven S, Lensing S, Ware J, Kilic F. Down-regulation of the serotonin transporter in hyperreactive platelets counteracts the pro-thrombotic effect of serotonin. J Mol Cell Cardiol. 2012 May; 52(5):1112-21. PMID: 22366712.
      View in: PubMed
    43. Jarvis GE, Bihan D, Hamaia S, Pugh N, Ghevaert CJ, Pearce AC, Hughes CE, Watson SP, Ware J, Rudd CE, Farndale RW. A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin alpha(2) beta(1). J Thromb Haemost. 2012; 10(2):268 - 277.
    44. Kanaji T, Ware J, Okamura T, Newman PJ. GPIba regulates platelet size by controlling the subcellular localization of filamin. Blood. 2012 Mar 22; 119(12):2906-13. PMID: 22174152.
      View in: PubMed
    45. Kanaji S, Kuether EL, Fahs SA, Schroeder JA, Ware J, Montgomery RR, Shi Q. Correction of murine Bernard-Soulier syndrome by lentivirus-mediated gene therapy. Mol Ther. 2012 Mar; 20(3):625-32. PMID: 22044935.
      View in: PubMed
    46. Li C, Piran S, Chen P, Lang S, Zarpellon A, Jin JW, Zhu G, Reheman A, Van der Wal DE, Simpson EK, Ni R, Gross PL, Ware J, Ruggeri ZM, Freedman J, Ni H. The maternal immune response to fetal platelet GPIb alpha causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies. J Clin Invest. 2011; 121(11):4537 - 4547.
    47. Li C, Piran S, Chen P, Lang S, Zarpellon A, Jin JW, Zhu G, Reheman A, van der Wal DE, Simpson EK, Ni R, Gross PL, Ware J, Ruggeri ZM, Freedman J, Ni H. The maternal immune response to fetal platelet GPIba causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies. J Clin Invest. 2011 Nov; 121(11):4537-47. PMID: 22019589.
      View in: PubMed
    48. Othman M, Lopez JA, Ware J. Platelet-type von Willebrand disease update: the disease, the molecule and the animal model. Expert Rev Hematol. 2011 Oct; 4(5):475-7. PMID: 21939413.
      View in: PubMed
    49. Ware J, Suva LJ. Platelets to hemostasis and beyond. Blood. 2011 Apr 07; 117(14):3703-4. PMID: 21474678.
      View in: PubMed
    50. Boilard E, Larabee K, Shnayder R, Jacobs K, Farndale RW, Ware J, Lee DM. Platelets participate in synovitis via Cox-1-dependent synthesis of prostacyclin independently of microparticle generation. J Immunol. 2011 Apr 01; 186(7):4361-6. PMID: 21357261.
      View in: PubMed
    51. Jain S, Harris J, Ware J. Platelets: linking hemostasis and cancer. Arterioscler Thromb Vasc Biol. 2010 Dec; 30(12):2362-7. PMID: 21071699.
      View in: PubMed
    52. Veeraputhiran M, Ware J, Dent J, Bornhorst J, Post G, Cottler-Fox M, Pesek G, Theus J, Nakagawa M. A comparison of washed and volume-reduced platelets with respect to platelet activation, aggregation, and plasma protein removal. Transfusion. 2011 May; 51(5):1030-6. PMID: 20946201.
      View in: PubMed
    53. Boilard E, Nigrovic PA, Larabee K, Watts GF, Coblyn JS, Weinblatt ME, Massarotti EM, Remold-O'Donnell E, Farndale RW, Ware J, Lee DM. Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science. 2010 Jan 29; 327(5965):580-3. PMID: 20110505.
      View in: PubMed
    54. Jain S, Ware J. The hemostasis/thrombosis paradigm in cancer. Hematology Education: the education program for the annual congress of the European Hematology Association. 2010; 4:302 - 305.
    55. Schmaier AA, Zou Z, Kazlauskas A, Emert-Sedlak L, Fong KP, Neeves KB, Maloney SF, Diamond SL, Kunapuli SP, Ware J, Brass LF, Smithgall TE, Saksela K, Kahn ML. Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role. Proc Natl Acad Sci U S A. 2009 Dec 15; 106(50):21167-72. PMID: 19940238.
      View in: PubMed
    56. Guerrero JA, Kyei M, Russell S, Liu J, Gartner TK, Storrie B, Ware J. Visualizing the von Willebrand factor/glycoprotein Ib-IX axis with a platelet-type von Willebrand disease mutation. Blood. 2009 Dec 24; 114(27):5541-6. PMID: 19808696.
      View in: PubMed
    57. Jain S, Russell S, Ware J. Platelet glycoprotein VI facilitates experimental lung metastasis in syngenic mouse models. J Thromb Haemost. 2009 Oct; 7(10):1713-7. PMID: 19624454.
      View in: PubMed
    58. Fontana G, Ware J, Cattaneo M. Haploinsufficiency of the platelet P2Y12 gene in a family with congenital bleeding diasthesis. Haematologica. 2009; 94(4):581 - 584.
    59. Fontana G, Ware J, Cattaneo M. Haploinsufficiency of the platelet P2Y12 gene in a family with congenital bleeding diathesis. Haematologica. 2009 Apr; 94(4):581-4. PMID: 19229056.
      View in: PubMed
    60. Liu J, Joglekar M, Ware J, Fitzgerald ME, Lowell CA, Berndt MC, Gartner TK. Evaluation of the physiological significance of botrocetin/ von Willebrand factor in vitro signaling. J Thromb Haemost. 2008; 6(11):1915 - 1922.
    61. Nishikii H, Eto K, Tamura N, Hattori K, Heissig B, Kanaji T, Sawaguchi A, Goto S, Ware J, Nakauchi H. Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells. J Exp Med. 2008 Aug 04; 205(8):1917-27. PMID: 18663123.
      View in: PubMed
    62. Suva LJ, Hartman E, Dilley JD, Russell S, Akel NS, Skinner RA, Hogue WR, Budde U, Varughese KI, Kanaji T, Ware J. Platelet dysfunction and a high bone mass phenotype in a murine model of platelet-type von Willebrand disease. Am J Pathol. 2008 Feb; 172(2):430-9. PMID: 18187573.
      View in: PubMed
    63. Guerrero JA, Shafirstein G, Russell S, Varughese KI, Kanaji T, Liu J, Gartner TK, Baumler W, Jarvis GE, Ware J. In vivo relevance for platelet glycoprotein Iba residue Tyr276 in thrombus formation. J Thromb Haemost. 2008; 6:684 - 691.
    64. Cheli Y, Jensen D, Marchese P, Habart D, Wiltshire T, Cooke M, Fernandez JA, Ware J, Ruggeri ZM, Kunicki TJ. The Modifier of hemostasis (Mh) locus on chromosome 4 controls in vivo hemostasis of Gp6-/- mice. Blood. 2008 Feb 01; 111(3):1266-73. PMID: 17991808.
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    65. Liu J, Ware J, Jackson CW, Gartner TK. FcRg-chain dependent allbb3 elicited outside-in signaling. J Thromb Haemost. 2007; 5(426):426 - 428 .
    66. Liu J, Ware J, Jackson CW, Gartner TK. FcRg-chain signals in the absence of GPVI. J Thromb Haemost. 2007; 5(201):201 - 203 .
    67. Jain S, Zuka M, Liu J, Russell S, Dent J, Guerrero JA, Forsyth J, Maruszak B, Gartner TK, Felding-Habermann B, Ware J. Platelet glycoprotein Ib alpha supports experimental lung metastasis. Proc Natl Acad Sci U S A. 2007 May 22; 104(21):9024-8. PMID: 17494758.
      View in: PubMed
    68. Jain S, Zuka M, Liu J, Russell S, Dent JA, Guerrero JA, Forsyth J, Maruszak B, Gartner TK, Felding-Habermann B, Ware J. Platelet glycoprotein Iba supports experimental lung metastasis. Proc Natl Acad Sci U S A. 2007; 104:9024 - 9028.
    69. Hughan SC, Hughes CE, McCarty OJ, Schweighoffer E, Soultanova I, Ware J, Tybulewicz VL, Watson SP. GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk. Arterioscler Thromb Vasc Biol. 2007 Feb; 27(2):422-9. PMID: 17110603.
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    70. Bergmeier W, Piffath CL, Goerge T, Cifuni SM, Ruggeri ZM, Ware J, Wagner DD. The role of platelet adhesion receptor GPIba far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis. Proc Natl Acad Sci U S A. 2006; 103(45):16900 - 16905.
    71. Bergmeier W, Piffath CL, Goerge T, Cifuni SM, Ruggeri ZM, Ware J, Wagner DD. The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16900-5. PMID: 17075060.
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    72. Martínez C, Corral J, Dent JA, Sesma L, Vicente V, Ware J. Platelet septin complexes form rings and associate with the microtubular network. J Thromb Haemost. 2006 Jun; 4(6):1388-95. PMID: 16706986.
      View in: PubMed
    73. Kisucka J, Butterfield CE, Duda DG, Eichenberger SC, Saffaripour S, Ware J, Ruggeri ZM, Jain RK, Folkman J, Wagner DD. Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage. Proc Natl Acad Sci U S A. 2006 Jan 24; 103(4):855-60. PMID: 16418262.
      View in: PubMed
    74. Konstantinides S, Ware J, Marchese P, Almus-Jacobs F, Loskutoff DJ, Ruggeri ZM. Distinct antithrombotic consequences of platelet glycoprotein Iba and VI deficiency in a mouse model of arterial thrombosis. J Thromb Haemost. 2006; 4:2014 - 2021.
    75. Ware J. Viral rescue of murine Glanzmann thrombasthenia. Blood. 2005; 106(8):2596 - 2596.
    76. Ware J. Controlled megakaryocytic gene expression. Blood. 2005; 106(5):1511 - 1512.
    77. Martinez C, Ware J. Mammalian septin function in hemostasis and beyond. Exp Biol Med (Maywood). 2004 Dec; 229(11):1111-9. PMID: 15564437.
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    78. Kanaji T, Russell S, Cunningham J, Izuhara K, Fox JE, Ware J. Megakaryocyte proliferation and ploidy regulated by the cytoplasmic tail of glycoprotein Iba. Blood. 2004; 104(10):3161 - 3168.
    79. Martínez C, Sanjuan MA, Dent JA, Karlsson L, Ware J. Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol. Biochem J. 2004 Sep 15; 382(Pt 3):783-91. PMID: 15214843.
      View in: PubMed
    80. Ware J. Dysfunctional platelet membrane receptors: from humans to mice. Thromb Haemost. 2004 Sep; 92(3):478-85. PMID: 15351843.
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    81. Kanaji T, Russell S, Cunningham J, Izuhara K, Fox JE, Ware J. Megakaryocyte proliferation and ploidy regulated by the cytoplasmic tail of glycoprotein Ibalpha. Blood. 2004 Nov 15; 104(10):3161-8. PMID: 15271795.
      View in: PubMed
    82. Kato K, Martinez C, Russell S, Nurden P, Nurden A, Fiering S, Ware J. Genetic deletion of mouse platelet glycoprotein Ibbeta produces a Bernard-Soulier phenotype with increased alpha-granule size. Blood. 2004 Oct 15; 104(8):2339-44. PMID: 15213102.
      View in: PubMed
    83. Federici AB, Canciani MT, Forza I, Mannucci PM, Marchese P, Ware J, Ruggeri ZM. A sensitive ristocetin co-factor activity assay with recombinant glycoprotein Ibalpha for the diagnosis of patients with low von Willebrand factor levels. Haematologica. 2004 Jan; 89(1):77-85. PMID: 14754609.
      View in: PubMed
    84. Federici AB, Canciani MT, Forza I, Mannucci PM, Marchese P, Ware J, Ruggeri ZM. A sensitive ristocetin co-factor activity assay with recombinant glycoprotein Iba for the diagnosis of patients with low von Willebrand factor levels. Haematologica. 2004; 89(1):77 - 85.
    85. Kanaji S, Kanaji T, Furihata K, Kato K, Ware JL, Kunicki TJ. Convulxin binds to native, human glycoprotein Ib alpha. J Biol Chem. 2003; 278(41):39452 - 39460.
    86. Kanaji S, Kanaji T, Furihata K, Kato K, Ware JL, Kunicki TJ. Convulxin binds to native, human glycoprotein Ib alpha. J Biol Chem. 2003 Oct 10; 278(41):39452-60. PMID: 12881531.
      View in: PubMed
    87. Celikel R, McClintock RA, Roberts JR, Mendolicchio GL, Ware J, Varughese KI, Ruggeri ZM. Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha. Science. 2003 Jul 11; 301(5630):218-21. PMID: 12855810.
      View in: PubMed
    88. Kato K, Kanaji T, Russell S, Kunicki TJ, Furihata K, Kanaji S, Marchese P, Reininger A, Ruggeri ZM, Ware J. The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion. Blood. 2003 Sep 01; 102(5):1701-7. PMID: 12738669.
      View in: PubMed
    89. Cattaneo M, Zighetti ML, Lombardi R, Martinez C, Lecchi A, Conley PB, Ware J, Ruggeri ZM. Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1978-83. PMID: 12578987.
      View in: PubMed
    90. Celikel R, McClintock RA, Roberts JR, Mendolicchio L, Ware J, Varughese KI, Ruggeri ZM. Modulation of a-thrombin function of distinct interactions with platelet glycoprotein Iba. Science. 2003; 301:218 - 221.
    91. Macara IG, Baldarelli R, Field CM, Glotzer M, Hayashi Y, Hsu SC, Kennedy MB, Kinoshita M, Longtine M, Low C, Maltais LJ, McKenzie L, Mitchison TJ, Nishikawa T, Noda M, Petty EM, Peifer M, Pringle JR, Robinson PJ, Roth D, Russell SE, Stuhlmann H, Tanaka M, Tanaka T, Trimble WS, Ware J, Zeleznik-Le NJ, Zieger B. Mammalian septins nomenclature. Mol Biol Cell. 2002 Dec; 13(12):4111-3. PMID: 12475938.
      View in: PubMed
    92. Kanaji T, Russell S, Ware J. Amelioration of the macrothrombocytopenia associated with the murine Bernard-Soulier syndrome. Blood. 2002 Sep 15; 100(6):2102-7. PMID: 12200373.
      View in: PubMed
    93. Poujol C, Ware J, Nieswandt B, Nurden AT, Nurden P. Absence of GPIbalpha is responsible for aberrant membrane development during megakaryocyte maturation: ultrastructural study using a transgenic model. Exp Hematol. 2002 Apr; 30(4):352-60. PMID: 11937271.
      View in: PubMed
    94. Dent J, Kato K, Peng XR, Martinez C, Cattaneo M, Poujol C, Nurden P, Nurden A, Trimble WS, Ware J. A prototypic platelet septin and its participation in secretion. Proc Natl Acad Sci U S A. 2002 Mar 05; 99(5):3064-9. PMID: 11880646.
      View in: PubMed
    95. Kasirer-Friede A, Ware J, Leng L, Marchese P, Ruggeri ZM, Shattil SJ. Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3. J Biol Chem. 2002 Apr 05; 277(14):11949-56. PMID: 11812775.
      View in: PubMed
    96. Peng XR, Jia Z, Zhang Y, Ware J, Trimble WS. The septin CDCrel-1 is dispensable for normal development and neurotransmitter release. Mol Cell Biol. 2002 Jan; 22(1):378-87. PMID: 11739749.
      View in: PubMed
    97. Kasirer-Friede A, Ware J, Leng L, Marchese P, Ruggeri ZM, Shattil SJ. Lateral clustering of platelet GP Ib-IX complexes leads to up- regulation of the adhesive function of integrin aIIbb3. J Biol Chem. 2002; 277:11949 - 11956.
    98. Dent JA, Kato K, Peng X, Martinez C, Cattaneo M, Poujol C, Nurden P, Nurden AT, Trimble WS, Ware J. A prototypic platelet septin and its participation in platelet secretion. Proc Natl Acad Sci USA. 2002; 99:3064 - 3069.
    99. Poujol C, Ware J, Nieswandt B, Nurden AT, Nurden P. Absence of GP Iba is responsible for an aberrant membrane development during megakaryocyte maturation: ultrastructural study using a transgenic model. Exp Hematology. 2002; 30:352 - 360.
    100. Ware J, Ruggeri ZM. Platelet adhesion receptors and their participation in hemostasis and thrombosis. Drugs Today (Barc). 2001 Apr; 37(4):265-274. PMID: 12768227.
      View in: PubMed
    101. Ware J, Ruggeri ZM. Platelet adhesion receptors and their participation in hemostasis and thrombosis. Drugs of Today. 2001; 37:265 - 274.
    102. Vasudevan S, Roberts JR, McClintock RA, Dent JA, Celikel R, Ware J, Varughese KI, Ruggeri ZM. Modeling and functional analysis of the interaction between von Willebrand factor A1 domain and glycoprotein Iba. J Biol Chem. 2000; 275:12763 - 12768.
    103. Ware J, Russell S, Ruggeri ZM. Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome. Proc Natl Acad Sci USA. 2000; 97:2803 - 2808.
    104. Zieger B, Tran H, Hainmann I, Wunderle D, Zgaga-Griesz A, Blaser S, Ware J. Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL1. Gene. 2000; 261:197 - 203.
    105. Andre P, Denis CV, Ware J, Saffaripour S, Hynes RO, Ruggeri ZM, Wagner DD. Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood. 2000; 96:3322 - 3328.
    106. Marchese P, Saldivar E, Ware J., Ruggeri ZM. Adhesive properties of the isolated amino terminal domain of platelet glycoprotein Iba in a flow field. Proc Natl Acad Sci USA. 1999; 96:7837 - 7842.
    107. Yagi M, Zieger B, Roth GJ, Ware J. Structure and expression of the human septin gene HCDCrel-1. Gene. 1998; 212:229 - 236.
    108. Ware J. Molecular analyses of the platelet glycoprotein Ib-IX-V receptor. Throm Haemost. 1998; 79:466 - 478.
    109. Fujita H, Hashimoto Y, Russell S, Zieger B, Ware J. In vivo expression of murine platelet glycoprotein Iba. Blood. 1998; 92:488 - 495.
    110. Federici AB, Mannucci PM, Stabile F, Canciani MT, Di Rocco N, Miyata S, Ware J, Ruggeri ZM. A type 2B von Willebrand disease mutation (Ile546 to Val) associated with an unusual phenotype. Throm Haemost. 1997; 78:1132 - 1137.
    111. Zieger B, Hashimoto Y, Ware J. Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence. J Clin Invest. 1997; 99(3):520 - 525.
    112. Zieger B, Ware J. Cloning and deduced amino acid sequence of human nicotinamide nucleotide transhydrogenase. DNA Seq. 1997; 7(6):369 - 374.
    113. Ware J, Russell S, Ruggeri ZM. Cloning of the murine platelet glycoprotein Iba gene highlighting species-specific platelet adhesion. Blood Cells Mol Dis. 1997; 23(2):292 - 301.
    114. Schneppenheim R, Brassard J, Krey S, Budde U, Kunicki TJ, Holmberg L, Ware J, Ruggeri ZM. Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease. Proc Natl Acad Sci USA. 1996; 93(8):3581 - 3586.
    115. Ware J, Hashimoto Y, Zieger B, Russell S. Controlling elements of platelet glycoprotein Iba expression. Comptes Rendus de l Academie des Sciences Serie Iii, Sciences de la Vie. 1996; 319(9):811 - 817.
    116. Miyata S, Goto S, Federici AB, Ware J, Ruggeri ZM. Conformational changes in the A1 domain of von Willebrand factor modulating the interaction with platelet glycoprotein Iba. J Biol Chem. 1996; 271(15):9046 - 9053.
    117. Hayashi T, Ware J, Niiya K, Sakuragawa N. Isolated recombinant domain of von Willebrand factor displaying increased sensitivity to ristocetin. Am J Hemat. 1996; 52(4):248 - 253.
    118. Marchese P, Murata M, Mazzucato M, Pradella P, De Marco L, Ware J, Ruggeri ZM. Identification of three tyrosine residues of glycoprotein Iba with distinct roles in von Willebrand factor and alpha-thrombin binding. J Biol Chem. 1995; 270(16):9571 - 9578.
    119. Hashimoto Y, Ware J. Identification of essential GATA and Ets binding motifs within the promoter of the platelet glycoprotein Iba gene. J Biol Chem. 1995; 270(41):24532 - 24539.
    120. Rivera J, Sanchez-Roig MJ, Rosillo MC, Moraleda JM, Vicente V. Stability of glycoproteins Ib/IX and IIb/IIIa during preparation and storage of platelet concentrates: detection by binding assays with epitope-defined monoclonal antibodies and physiological ligands. Vox Sang. 1994; 67(2):166 - 171.
    121. Holmberg L, Dent JA, Schneppenheim R, Budde U, Ware J, Ruggeri ZM. von Willebrand factor mutation enhancing interaction with platelets in patients with normal multimeric structure. J Clin Invest. 1993; 91(5):2169 - 2177.
    122. Murata M, Russell SR, Ruggeri ZM, Ware J. Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Iba fragment. J Clin Invest. 1993; 91(5):2133 - 2137.
    123. Azuma H, Hayashi T, Dent JA, Ruggeri ZM, Ware J. Disulfide bond requirements for assembly of the platelet glycoprotein Ib-binding domain of von Willebrand factor. J Biol Chem. 1993; 268(4):2821 - 2827.
    124. Ware J, Russell SR, Marchese P, Ruggeri ZM. Expression of human platelet glycoprotein Iba in transgenic mice. J Biol Chem. 1993; 268(11):8376 - 8382.
    125. Sugimoto M, Dent J, McClintock R, Ware J, Ruggeri ZM. Analysis of structure-function relationships in the platelet membrane glycoprotein Ib-binding domain of von Willebrand's factor by expression of deletion mutants. J Biol Chem. 1993; 268(16):12185 - 12192.
    126. Prior CP, Chu V, Cambou B, Dent JA, Ebert B, Gore R, Holt J, Irish T, Lee J, Mitschelen J, McClintock RA, Searfoss G, Ricca GA, Tarr C, Weber D, Ware JL, Ruggeri ZM, Hrinda M, Ware J. Optimization of a recombinant von Willebrand factor fragment as an antagonist of the platelet glycoprotein Ib receptor. Bio/Technology. 1993; 11:709 - 713.
    127. Ware J, Russell SR, Marchese P, Murata M, Mazzucato M, De Marco L, Ruggeri ZM. Point mutation in a leucine-rich repeat of platelet glycoprotein Ib alpha resulting in the Bernard-Soulier syndrome. J Clin Invest. 1993; 92(3):1213 - 1220.
    128. Azuma H, Sugimoto M, Ruggeri ZM, Ware J. A role for von Willebrand factor proline residues 702-704 in ristocetin-mediated binding to platelet glycoprotein Ib. Throm Haemost. 1993; 69(2):192 - 196.
    129. Ruggeri ZM, Ware J. von Willebrand factor. FASEB J. 1993; 7(2):308 - 316.
    130. Ware J, MacDonald MJ, Lo M, De Graaf S, Fulcher CA. Epitope mapping of human factor VIII inhibitor antibodies by site-directed mutagenesis of a factor VIII polypeptide. Blood Coagulation and Fibrinolysis. 1992; 3(6):703 - 716.
    131. Murata M, Furihata K, Ishida F, Russell SR, Ware J, Ruggeri ZM. Genetic and structural characterization of an amino acid dimorphism in glycoprotein Iba involved in platelet transfusion refractoriness. Blood. 1992; 79(11):3086 - 3090.
    132. Ruggeri ZM, Ware J. The structure and function of von Willebrand factor. Throm Haemost. 1992; 67(6):594 - 599.
    133. Ware J, Dent JA, Azuma H, Sugimoto M, Kyrle PA, Yoshioka A, Ruggeri, ZM. Identification of a point mutation in type IIB von Willebrand disease illustrating the regulation of von Willebrand factor affinity for the platelet membrane glycoprotein Ib-IX receptor. Proc Natl Acad Sci USA. 1991; 88(7):2946 - 2950.
    134. Murata M, Ware J, Ruggeri ZM. Site-directed mutagenesis of a soluble recombinant fragment of platelet glycoprotein Iba demonstrating negatively charged residues involved in von Willebrand factor binding. J Biol Chem. 1991; 266(23):15474 - 15480.
    135. Azuma H, Dent JA, Sugimoto M, Ruggeri ZM, Ware J. Independent assembly and secretion of a dimeric adhesive domain of von Willebrand factor containing the glycoprotein Ib-binding site. J Biol Chem. 1991; 266(19):12342 - 12347.
    136. Dent JA, Berkowitz SD, Ware J, Kasper CK, Ruggeri ZM. Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor [published erratum appears in Proc Natl Acad Sci U S A 1990 Dec;87(23):9508]. Proc Natl Acad Sci USA. 1990; 87(16):6306 - 6310.
    137. Wu SM, Stafford DW, Ware J. Deduced amino acid sequence of mouse blood-coagulation factor IX. Gene. 1990; 86(2):275 - 278.
    138. Ware J, Russell SR, Vicente V, Scharf RE, Tomer A, McMillan R, Ruggeri ZM. Nonsense mutation in the glycoprotein Iba coding sequence associated with Bernard-Soulier syndrome. Proc Natl Acad Sci USA. 1990; 87(5):2026 - 2030.
    139. Ware J, Toomey JR, Stafford DW. Epitope localization of anti-factor VIII monoclonal antibodies determined by recombinant peptides. Throm Haemost. 1989; 61(2):225 - 229.
    140. Evans JP, Watzke HH, Ware JL, Stafford DW, High KA. Molecular cloning of a cDNA encoding canine factor IX. Blood. 1989; 74(1):207 - 212.
    141. Shima M, Ware J, Yoshioka A, Fukui H, Fulcher CA. An arginine to cysteine amino acid substitution at a critical thrombin cleavage site in a dysfunctional factor VIII molecule. Blood. 1989; 74(5):1612 - 1617.
    142. Ware J, Diuguid DL, Liebman HA, Rabiet MJ, Kasper CK, Furie BC, Furie B, Stafford DW. Factor IX San Dimas. Substitution of glutamine for Arg-4 in the propeptide leads to incomplete gamma-carboxylation and altered phospholipid binding properties. J Biol Chem. 1989; 264(19):11401 - 11406.
    143. Lubahn BC, Ware J, Stafford DW, Reisner HM. Identification of a F.VIII epitope recognized by a human hemophilic inhibitor. Blood. 1989; 73(2):497 - 499.
    144. Frazier D, Smith KJ, Cheung WF, Ware J, Lin SW, Thompson AR, Reisner, H, Bajaj SP, Stafford DW. Mapping of monoclonal antibodies to human factor IX. Blood. 1989; 74(3):971 - 977.
    145. Graham JB, Lubahn DB, Lord ST, Kirshtein J, Nilsson IM, Wallmark A, Ljung R, Frazier LD, Ware JL, Lin SW, Et al. The Malmo polymorphism of coagulation factor IX, an immunologic polymorphism due to dimorphism of residue 148 that is in linkage disequilibrium with two other F.IX polymorphisms. Am J Hum Genet. 1988; 42(4):573 - 580.
    146. Ware J, Davis L, Frazier D, Bajaj SP, Stafford DW. Genetic defect responsible for the dysfunctional protein: factor IXLong Beach. Blood. 1988; 72(2):820 - 822.
    147. Ware J, Toomey JR, Stafford DW. Localization of a factor VIII-inhibiting antibody epitope to a region between residues 338 and 362 of factor VIII heavy chain. Proc Natl Acad Sci USA. 1988; 85(9):3165 - 3169.
    148. Davis LM, McGraw RA, Ware JL, Roberts HR, Stafford DW. Factor IXAlabama: a point mutation in a clotting protein results in hemophilia B. Blood. 1987; 69(1):140 - 143.
    149. Rebbe NF, Ware J, Bertina RM, Modrich P, Stafford DW. Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family. Gene. 1987; 53(2-3):235 - 245.
    150. Ware JL, Sharp ZD, Cave MD. The ribosomal DNA transcription unit of the house cricket, Acheta domesticus. Biochem Genet. 1987; 25(5-6):345 - 358.
    151. Sharp ZD, Meriwether A, Ware J, Cave MD. Analysis of a large nontranscribed spacer in the ribosomal DNA of the house cricket, Acheta domesticus (Orthoptera:Gryllidae). Biochem Genet. 1986 Dec; 24(11-12):911-23. PMID: 3026306.
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    152. Benes H, Ware J, Cave MD. Analysis of genes for 5S rRNA from the cricket, Acheta domesticus: two classes of repeating units. Gene. 1985; 36(1-2):113-22. PMID: 2998928.
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