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Jia Liu

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentMicrobiology & Immunology, College of Medicine
DivisionMicrobiology & Immunology Faculty
Address325 S. Elm St.
Mail Slot # 511
Little Rock AR 72205
Phone501-686-7224
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    Collapse Research 
    Collapse research activities and funding
    1P30GM145393     (CANNON, MARTIN)May 5, 2022 - Apr 30, 2027
    NIH/Nat. Inst. of General Medical Sciences
    Center for Microbial Pathogenesis and Host Inflammatory Responses
    Role: Principal Investigator
    1P30GM145393-01     (CANNON, MARTIN)May 5, 2022 - Apr 30, 2027
    NIH/Nat. Inst. of General Medical Sciences
    Center for Microbial Pathogenesis and Host Inflammatory Responses
    Role: Principal Investigator
    5P30GM145393     (CANNON, MARTIN)May 5, 2022 - Apr 30, 2027
    NIH/Nat. Inst. of General Medical Sciences
    Center for Microbial Pathogenesis and Host Inflammatory Responses
    Role: Principal Investigator
    5P30GM145393-02     (CANNON, MARTIN)May 5, 2022 - Apr 30, 2027
    NIH/Nat. Inst. of General Medical Sciences
    Center for Microbial Pathogenesis and Host Inflammatory Responses
    Role: Principal Investigator
    P30GM145393     (SMELTZER, MARK S)May 5, 2022 - Apr 30, 2027
    NIH/Nat. Inst. of General Medical Sciences
    Center for Microbial Pathogenesis and Host Inflammatory Responses
    Role: Principal Investigator
    Barton FY19     (EOFF, ROBERT L)Feb 1, 2019 - Jan 31, 2020
    UAMS College of Medicine
    No FP attached
    Role: Principal Investigator
    BartonFY19     (EOFF, ROBERT L)Feb 1, 2019 - Jan 31, 2020
    UAMS College of Medicine
    No FP attached
    Role: Principal Investigator
    R01AI139106     (LIU, JIA)Jan 1, 2019 - Dec 31, 2024
    NIH
    Studies in Poxvirus Evasion of SAMD9 Pathway
    Role: Principal Investigator
    117     (CHILDS, GWEN V)Jul 1, 2015 - Jun 30, 2016
    UAMS College of Medicine
    No FP attached
    Role: Principal Investigator
    117-1009263     (LIU, JIA)Jul 1, 2015 - Jun 30, 2016
    UAMS College of Medicine
    Microbiology Liu Start-up Account
    Role: Principal Investigator
    K22AI099184     (LIU, JIA)Jun 15, 2013 - May 31, 2016
    NIH
    Characterization of Antiviral Functions of Sterile Alpha Motif-Containing Domain
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Conrad SJ, Liu J. Poxviruses as Gene Therapy Vectors: Generating Poxviral Vectors Expressing Therapeutic Transgenes. Methods Mol Biol. 2019; 1937:189-209. PMID: 30706397.
      View in: PubMed
    2. Esteves PJ, Abrantes J, Baldauf HM, BenMohamed L, Chen Y, Christensen N, Gonz?lez-Gallego J, Giacani L, Hu J, Kaplan G, Keppler OT, Knight KL, Kong XP, Lanning DK, Le Pendu J, de Matos AL, Liu J, Liu S, Lopes AM, Lu S, Lukehart S, Manabe YC, Neves F, McFadden G, Pan R, Peng X, de Sousa-Pereira P, Pinheiro A, Rahman M, Ruvo?n-Clouet N, Subbian S, Tu??n MJ, van der Loo W, Vaine M, Via LE, Wang S, Mage R. The wide utility of rabbits as models of human diseases. Exp Mol Med. 2018 05 22; 50(5):1-10. PMID: 29789565.
      View in: PubMed
    3. Nounamo B, Liem J, Cannon M, Liu J. Myxoma Virus Optimizes Cisplatin for the Treatment of Ovarian Cancer In?Vitro and in a Syngeneic Murine Dissemination Model. Mol Ther Oncolytics. 2017 Sep 15; 6:90-99. PMID: 28875159.
      View in: PubMed
    4. Nounamo B, Li Y, O'Byrne P, Kearney AM, Khan A, Liu J. An interaction domain in human SAMD9 is essential for myxoma virus host-range determinant M062 antagonism of host anti-viral function. Virology. 2017 03; 503:94-102. PMID: 28157624.
      View in: PubMed
    5. Liem J, Liu J. Stress Beyond Translation: Poxviruses and More. Viruses. 2016 06 14; 8(6). PMID: 27314378.
      View in: PubMed
    6. Tosic V, Thomas DL, Kranz DM, Liu J, McFadden G, Shisler JL, MacNeill AL, Roy EJ. Myxoma virus expressing a fusion protein of interleukin-15 (IL15) and IL15 receptor alpha has enhanced antitumor activity. PLoS One. 2014; 9(10):e109801. PMID: 25329832.
      View in: PubMed
    7. Rahman MM, Liu J, Chan WM, Rothenburg S, McFadden G. Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9 to promote expanded host tropism and viral replication. PLoS Pathog. 2013; 9(7):e1003465. PMID: 23853588.
      View in: PubMed
    8. Lemos de Matos A, Liu J, McFadden G, Esteves PJ. Evolution and divergence of the mammalian SAMD9/SAMD9L gene family. BMC Evol Biol. 2013 Jun 12; 13:121. PMID: 23758988.
      View in: PubMed
    9. Doty RA, Liu J, McFadden G, Roy EJ, MacNeill AL. Histological evaluation of intratumoral myxoma virus treatment in an immunocompetent mouse model of melanoma. Oncolytic Virother. 2013 Jan; 2:1-17. PMID: 25866742.
      View in: PubMed
    10. Liu J, Rothenburg S, McFadden G. The poxvirus C7L host range factor superfamily. Curr Opin Virol. 2012 Dec; 2(6):764-72. PMID: 23103013.
      View in: PubMed
    11. Urbasic AS, Hynes S, Somrak A, Contakos S, Rahman MM, Liu J, MacNeill AL. Oncolysis of canine tumor cells by myxoma virus lacking the serp2 gene. Am J Vet Res. 2012 Aug; 73(8):1252-61. PMID: 22849686.
      View in: PubMed
    12. Wennier ST, Liu J, McFadden G. Bugs and drugs: oncolytic virotherapy in combination with chemotherapy. Curr Pharm Biotechnol. 2012 Jul; 13(9):1817-33. PMID: 21740354.
      View in: PubMed
    13. Cao H, Dai P, Wang W, Li H, Yuan J, Wang F, Fang CM, Pitha PM, Liu J, Condit RC, McFadden G, Merghoub T, Houghton AN, Young JW, Shuman S, Deng L. Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain. PLoS One. 2012; 7(5):e36823. PMID: 22606294.
      View in: PubMed
    14. Liu J, Wennier S, Moussatche N, Reinhard M, Condit R, McFadden G. Myxoma virus M064 is a novel member of the poxvirus C7L superfamily of host range factors that controls the kinetics of myxomatosis in European rabbits. J Virol. 2012 May; 86(9):5371-5. PMID: 22379095.
      View in: PubMed
    15. Wennier ST, Liu J, Li S, Rahman MM, Mona M, McFadden G. Myxoma virus sensitizes cancer cells to gemcitabine and is an effective oncolytic virotherapeutic in models of disseminated pancreatic cancer. Mol Ther. 2012 Apr; 20(4):759-68. PMID: 22233582.
      View in: PubMed
    16. Thomas DL, Doty R, Tosic V, Liu J, Kranz DM, McFadden G, Macneill AL, Roy EJ. Myxoma virus combined with rapamycin treatment enhances adoptive T cell therapy for murine melanoma brain tumors. Cancer Immunol Immunother. 2011 Oct; 60(10):1461-72. PMID: 21656158.
      View in: PubMed
    17. Liu J, Wennier S, Zhang L, McFadden G. M062 is a host range factor essential for myxoma virus pathogenesis and functions as an antagonist of host SAMD9 in human cells. J Virol. 2011 Apr; 85(7):3270-82. PMID: 21248034.
      View in: PubMed
    18. France MR, Thomas DL, Liu J, McFadden G, MacNeill AL, Roy EJ. Intraventricular injection of myxoma virus results in transient expression of viral protein in mouse brain ependymal and subventricular cells. J Gen Virol. 2011 Jan; 92(Pt 1):195-9. PMID: 20861319.
      View in: PubMed
    19. Liu J, Wennier S, McFadden G. The immunoregulatory properties of oncolytic myxoma virus and their implications in therapeutics. Microbes Infect. 2010 Dec; 12(14-15):1144-52. PMID: 20832500.
      View in: PubMed
    20. Van Vliet K, Mohamed MR, Zhang L, Villa NY, Werden SJ, Liu J, McFadden G. Poxvirus proteomics and virus-host protein interactions. Microbiol Mol Biol Rev. 2009 Dec; 73(4):730-49. PMID: 19946139.
      View in: PubMed
    21. Zhang L, Stanford M, Liu J, Barrett C, Jiang L, Barclay AN, McFadden G. Inhibition of macrophage activation by the myxoma virus M141 protein (vCD200). J Virol. 2009 Sep; 83(18):9602-7. PMID: 19570854.
      View in: PubMed
    22. Liu J, Wennier S, Reinhard M, Roy E, MacNeill A, McFadden G. Myxoma virus expressing interleukin-15 fails to cause lethal myxomatosis in European rabbits. J Virol. 2009 Jun; 83(11):5933-8. PMID: 19279088.
      View in: PubMed
    23. Liu J, Saghizadeh M, Tuli SS, Kramerov AA, Lewin AS, Bloom DC, Hauswirth WW, Castro MG, Schultz GS, Ljubimov AV. Different tropism of adenoviruses and adeno-associated viruses to corneal cells: implications for corneal gene therapy. Mol Vis. 2008; 14:2087-96. PMID: 19023450.
      View in: PubMed
    24. Liu J, Lewin AS, Tuli SS, Ghivizzani SC, Schultz GS, Bloom DC. Reduction in severity of a herpes simplex virus type 1 murine infection by treatment with a ribozyme targeting the UL20 gene RNA. J Virol. 2008 Aug; 82(15):7467-74. PMID: 18508896.
      View in: PubMed
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