 Virus Activation
"Virus Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The mechanism by which latent viruses, such as genetically transmitted tumor viruses (PROVIRUSES) or PROPHAGES of lysogenic bacteria, are induced to replicate and then released as infectious viruses. It may be effected by various endogenous and exogenous stimuli, including B-cell LIPOPOLYSACCHARIDES, glucocorticoid hormones, halogenated pyrimidines, IONIZING RADIATION, ultraviolet light, and superinfecting viruses.
| Descriptor ID |
D014775
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| MeSH Number(s) |
G06.590.875.780.940 G06.920.875.780.940
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| Concept/Terms |
Virus Activation- Virus Activation
- Activation, Virus
- Activations, Virus
- Virus Activations
- Viral Activation
- Activation, Viral
- Activations, Viral
- Viral Activations
- Virus Induction
- Induction, Virus
- Inductions, Virus
- Virus Inductions
Prophage Induction- Prophage Induction
- Induction, Prophage
- Inductions, Prophage
- Prophage Inductions
Prophage Excision- Prophage Excision
- Excision, Prophage
- Excisions, Prophage
- Prophage Excisions
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Below are MeSH descriptors whose meaning is more general than "Virus Activation".
Below are MeSH descriptors whose meaning is more specific than "Virus Activation".
This graph shows the total number of publications written about "Virus Activation" by people in UAMS Profiles by year, and whether "Virus Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 0 | 1 | 1 | | 2022 | 1 | 1 | 2 | | 2021 | 1 | 0 | 1 | | 2020 | 4 | 0 | 4 | | 2019 | 1 | 2 | 3 | | 2017 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2010 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2007 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Virus Activation" by people in Profiles over the past ten years.
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Chen J, Fan J, Malaviarachchi PA, Post SR, Lin Z, Zhang X, Qin Z. Alterations in Cellular Gene Expression Due to Co-Infection With Kaposi's Sarcoma-Associated Herpesvirus and SARS-CoV-2: Implications for Disease Severity. J Med Virol. 2025 Jan; 97(1):e70149.
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Gupta A, Owens SM, Oldenburg DG, White DW, Forrest JC. Lytic Replication and Reactivation from B Cells Is Not Required for Establishing or Maintaining Gammaherpesvirus Latency In Vivo. J Virol. 2022 06 22; 96(12):e0069022.
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Chen J, Dai L, Kendrick S, Post SR, Qin Z. The Anti-COVID-19 Drug Remdesivir Promotes Oncogenic Herpesvirus Reactivation through Regulation of Intracellular Signaling Pathways. Antimicrob Agents Chemother. 2022 03 15; 66(3):e0239521.
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Chen J, Dai L, Barrett L, James J, Plaisance-Bonstaff K, Post SR, Qin Z. SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus. Commun Biol. 2021 06 03; 4(1):682.
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Owens SM, Oldenburg DG, White DW, Forrest JC. Deletion of Murine Gammaherpesvirus Gene M2 in Activation-Induced Cytidine Deaminase-Expressing B Cells Impairs Host Colonization and Viral Reactivation. J Virol. 2020 12 09; 95(1).
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Dai L, Jung BG, Chen J, Samten B, Forrest JC, Post SR, Qin Z. The potential impacts of early secreted antigenic target of 6?kDa of Mycobacterium tuberculosis on KSHV-infected cells. J Med Virol. 2021 06; 93(6):4028-4032.
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Dai L, Barrett L, Plaisance-Bonstaff K, Post SR, Qin Z. Porphyromonas gingivalis coinfects with KSHV in oral cavities of HIV+ patients and induces viral lytic reactivation. J Med Virol. 2020 Dec; 92(12):3862-3867.
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Dai L, Qiao J, Yin J, Goldstein A, Lin HY, Post SR, Qin Z. Kaposi Sarcoma-Associated Herpesvirus and Staphylococcus aureus Coinfection in Oral Cavities of HIV-Positive Patients: A Unique Niche for Oncogenic Virus Lytic Reactivation. J Infect Dis. 2020 03 28; 221(8):1331-1341.
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Chen J, Dai L, Goldstein A, Zhang H, Tang W, Forrest JC, Post SR, Chen X, Qin Z. Identification of new antiviral agents against Kaposi's sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation. PLoS Pathog. 2019 12; 15(12):e1008156.
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Chen J, Del Valle L, Lin HY, Plaisance-Bonstaff K, Forrest JC, Post SR, Qin Z. Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation. Virology. 2019 10; 536:16-19.
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Gao Y, Wang L, Lei Z, Li J, Forrest JC, Liang X. IRF4 promotes Epstein-Barr virus activation in Burkitt's lymphoma cells. J Gen Virol. 2019 05; 100(5):851-862.
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Varma A, Biritxinaga L, Saliba RM, Stich M, Jauch SF, Afrough A, Honhar M, Popat UR, Shafi MA, Shah N, Bashir Q, Dinh Y, Hosing C, Champlin RE, Qazilbash MH. Impact of Hepatitis B Core Antibody Seropositivity on the Outcome of Autologous Hematopoietic Stem Cell Transplantation for Multiple Myeloma. Biol Blood Marrow Transplant. 2017 Apr; 23(4):581-587.
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