Genes, ras
"Genes, ras" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.
Descriptor ID |
D011905
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MeSH Number(s) |
G05.360.340.024.340.375.500.791.550
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Concept/Terms |
Ha-ras Genes- Ha-ras Genes
- Gene, Ha-ras
- Genes, Ha-ras
- Ha ras Genes
- Ha-ras Gene
Ki-ras Genes- Ki-ras Genes
- Gene, Ki-ras
- Genes, Ki-ras
- Ki ras Genes
- Ki-ras Gene
N-ras Genes- N-ras Genes
- Genes, N-ras
- N ras Genes
- N-ras Gene
- N-ras Oncogenes
- N ras Oncogenes
- N-ras Oncogene
v-Ha-ras Genes- v-Ha-ras Genes
- Gene, v-Ha-ras
- Genes, v-Ha-ras
- v Ha ras Genes
- v-Ha-ras Gene
v-Ki-ras Genes- v-Ki-ras Genes
- Gene, v-Ki-ras
- Genes, v-Ki-ras
- v Ki ras Genes
- v-Ki-ras Gene
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Below are MeSH descriptors whose meaning is more general than "Genes, ras".
Below are MeSH descriptors whose meaning is more specific than "Genes, ras".
This graph shows the total number of publications written about "Genes, ras" by people in UAMS Profiles by year, and whether "Genes, ras" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2017 | 1 | 0 | 1 | 2016 | 0 | 2 | 2 | 2014 | 1 | 1 | 2 | 2013 | 1 | 1 | 2 | 2012 | 2 | 0 | 2 | 2011 | 0 | 1 | 1 | 2008 | 1 | 1 | 2 | 2006 | 1 | 0 | 1 | 2005 | 3 | 0 | 3 | 2001 | 1 | 1 | 2 | 2000 | 0 | 1 | 1 | 1997 | 3 | 1 | 4 | 1996 | 0 | 1 | 1 | 1995 | 2 | 1 | 3 | 1994 | 1 | 0 | 1 | 1993 | 1 | 2 | 3 | 1990 | 1 | 0 | 1 | 1989 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, ras" by people in Profiles over the past ten years.
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Romero R, Sayin VI, Davidson SM, Bauer MR, Singh SX, LeBoeuf SE, Karakousi TR, Ellis DC, Bhutkar A, Sánchez-Rivera FJ, Subbaraj L, Martinez B, Bronson RT, Prigge JR, Schmidt EE, Thomas CJ, Goparaju C, Davies A, Dolgalev I, Heguy A, Allaj V, Poirier JT, Moreira AL, Rudin CM, Pass HI, Vander Heiden MG, Jacks T, Papagiannakopoulos T. Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis. Nat Med. 2017 Nov; 23(11):1362-1368.
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Wang Y, Chang J, Liu X, Zhang X, Zhang S, Zhang X, Zhou D, Zheng G. Discovery of piperlongumine as a potential novel lead for the development of senolytic agents. Aging (Albany NY). 2016 11 19; 8(11):2915-2926.
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Weinhold N, Ashby C, Rasche L, Chavan SS, Stein C, Stephens OW, Tytarenko R, Bauer MA, Meissner T, Deshpande S, Patel PH, Buzder T, Molnar G, Peterson EA, van Rhee F, Zangari M, Thanendrarajan S, Schinke C, Tian E, Epstein J, Barlogie B, Davies FE, Heuck CJ, Walker BA, Morgan GJ. Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma. Blood. 2016 09 29; 128(13):1735-44.
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Zhang W, Nandakumar N, Shi Y, Manzano M, Smith A, Graham G, Gupta S, Vietsch EE, Laughlin SZ, Wadhwa M, Chetram M, Joshi M, Wang F, Kallakury B, Toretsky J, Wellstein A, Yi C. Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma. Sci Signal. 2014 May 06; 7(324):ra42.
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Melchor L, Brioli A, Wardell CP, Murison A, Potter NE, Kaiser MF, Fryer RA, Johnson DC, Begum DB, Hulkki Wilson S, Vijayaraghavan G, Titley I, Cavo M, Davies FE, Walker BA, Morgan GJ. Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma. Leukemia. 2014 Aug; 28(8):1705-15.
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Levinsohn JL, Teng J, Craiglow BG, Loring EC, Burrow TA, Mane SS, Overton JD, Lifton RP, McNiff JM, Lucky AW, Choate KA. Somatic HRAS p.G12S mutation causes woolly hair and epidermal nevi. J Invest Dermatol. 2014 Apr; 134(4):1149-1152.
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