 Neutrophils
"Neutrophils" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
| Descriptor ID |
D009504
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| MeSH Number(s) |
A11.118.637.415.583 A11.627.340.583 A11.733.689 A15.145.229.637.415.583 A15.382.490.315.583 A15.382.680.689
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| Concept/Terms |
Neutrophils- Neutrophils
- Neutrophil
- Polymorphonuclear Leukocytes
- Leukocytes, Polymorphonuclear
- Leukocyte, Polymorphonuclear
- Polymorphonuclear Leukocyte
LE Cells- LE Cells
- Cell, LE
- Cells, LE
- LE Cell
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Below are MeSH descriptors whose meaning is more general than "Neutrophils".
Below are MeSH descriptors whose meaning is more specific than "Neutrophils".
This graph shows the total number of publications written about "Neutrophils" by people in UAMS Profiles by year, and whether "Neutrophils" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 1 | 0 | 1 | | 2019 | 2 | 1 | 3 | | 2018 | 1 | 2 | 3 | | 2017 | 3 | 1 | 4 | | 2016 | 3 | 4 | 7 | | 2015 | 5 | 5 | 10 | | 2014 | 2 | 4 | 6 | | 2013 | 5 | 1 | 6 | | 2012 | 3 | 1 | 4 | | 2011 | 4 | 3 | 7 | | 2010 | 0 | 1 | 1 | | 2009 | 1 | 3 | 4 | | 2008 | 2 | 0 | 2 | | 2007 | 0 | 2 | 2 | | 2006 | 1 | 2 | 3 | | 2005 | 2 | 2 | 4 | | 2004 | 2 | 1 | 3 | | 2003 | 0 | 3 | 3 | | 2002 | 3 | 4 | 7 | | 2001 | 1 | 0 | 1 | | 2000 | 1 | 2 | 3 | | 1998 | 2 | 3 | 5 | | 1997 | 1 | 0 | 1 | | 1995 | 3 | 0 | 3 | | 1994 | 0 | 4 | 4 | | 1993 | 1 | 2 | 3 | | 1992 | 0 | 1 | 1 | | 1991 | 2 | 2 | 4 | | 1990 | 1 | 1 | 2 | | 1989 | 0 | 1 | 1 | | 1988 | 1 | 1 | 2 |
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Below are the most recent publications written about "Neutrophils" by people in Profiles over the past ten years.
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Kallen ME, Koka R, Singh Z, Sanchez-Petitto G, Zaman QU, Yared JA, Duong VH. Teenage mutant neutrophilic precursors: Leukemia cutis with IDH2 mutation on enasidenib therapy. Leuk Res. 2020 09; 96:106406.
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Majors I, Jagadale VS. Serum interleukin 6 could be a valuable initial diagnostic tool in prosthetic knee joint infections. Eur J Orthop Surg Traumatol. 2019 Dec; 29(8):1781-1788.
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Svahn SL, Gutiérrez S, Ulleryd MA, Nookaew I, Osla V, Beckman F, Nilsson S, Karlsson A, Jansson JO, Johansson ME. Dietary Polyunsaturated Fatty Acids Promote Neutrophil Accumulation in the Spleen by Altering Chemotaxis and Delaying Cell Death. Infect Immun. 2019 08; 87(8).
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Cockburn CL, Green RS, Damle SR, Martin RK, Ghahrai NN, Colonne PM, Fullerton MS, Conrad DH, Chalfant CE, Voth DE, Rucks EA, Gilk SD, Carlyon JA. Functional inhibition of acid sphingomyelinase disrupts infection by intracellular bacterial pathogens. Life Sci Alliance. 2019 04; 2(2).
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Levy H, Jia S, Pan A, Zhang X, Kaldunski M, Nugent ML, Reske M, Feliciano RA, Quintero D, Renda MM, Woods KJ, Murkowski K, Johnson K, Verbsky J, Dasu T, Ideozu JE, McColley S, Quasney MW, Dahmer MK, Avner E, Farrell PM, Cannon CL, Jacob H, Simpson PM, Hessner MJ. Identification of molecular signatures of cystic fibrosis disease status with plasma-based functional genomics. Physiol Genomics. 2019 01 01; 51(1):27-41.
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Pierre-Louis WS, Bath J, Mikkilineni S, Scott MC, Harlander-Locke M, Rasor Z, Smeds M. Neutrophil to Lymphocyte Ratio as a Predictor of Outcomes after Amputation. Ann Vasc Surg. 2019 Jan; 54:84-91.
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Claushuis TAM, de Stoppelaar SF, de Vos AF, Grootemaat AE, van der Wel NN, Roelofs JJTH, Ware J, Van't Veer C, van der Poll T. Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis. Arterioscler Thromb Vasc Biol. 2018 08; 38(8):1772-1784.
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Cheung DS, Sigua JA, Simpson PM, Yan K, Hussain SA, Santoro JL, Buell EJ, Hunter DA, Rohlfing M, Patadia D, Grayson MH. Cysteinyl leukotriene receptor 1 expression identifies a subset of neutrophils during the antiviral response that contributes to postviral atopic airway disease. J Allergy Clin Immunol. 2018 10; 142(4):1206-1217.e5.
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Naglak EK, Morrison SG, Morrison RP. Neutrophils Are Central to Antibody-Mediated Protection against Genital Chlamydia. Infect Immun. 2017 10; 85(10).
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Kern M, Shiver MB, Addis KM, Gardner JM. Palisaded Neutrophilic and Granulomatous Dermatitis/Interstitial Granulomatous Dermatitis Overlap: A Striking Clinical and Histologic Presentation With "Burning Rope Sign" and Subsequent Mirror-Image Contralateral Recurrence. Am J Dermatopathol. 2017 Sep; 39(9):e141-e146.
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Pechous RD. With Friends Like These: The Complex Role of Neutrophils in the Progression of Severe Pneumonia. Front Cell Infect Microbiol. 2017; 7:160.
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Maes M, McGill MR, da Silva TC, Abels C, Lebofsky M, Weemhoff JL, Tiburcio T, Veloso Alves Pereira I, Willebrords J, Crespo Yanguas S, Farhood A, Beschin A, Van Ginderachter JA, Penuela S, Jaeschke H, Cogliati B, Vinken M. Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity. Arch Toxicol. 2017 May; 91(5):2245-2261.
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Faller DV, Castaneda SA, Zhou D, Vedamony M, Newburger PE, White GL, Kosanke S, Plett PA, Orschell CM, Boosalis MS, Perrine SP. An oral HemokineTM, a-methylhydrocinnamate, enhances myeloid and neutrophil recovery following irradiation in vivo. Blood Cells Mol Dis. 2017 03; 63:1-8.
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Emanuelli T, Burgeiro A, Carvalho E. Effects of insulin on the skin: possible healing benefits for diabetic foot ulcers. Arch Dermatol Res. 2016 Dec; 308(10):677-694.
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Goh BK, Teo JY, Allen JC, Tan DM, Chan CY, Lee SY, Tai DW, Thng CH, Cheow PC, Chow PK, Ooi LL, Chung AY. Preoperative platelet-to-lymphocyte ratio improves the performance of the international consensus guidelines in predicting malignant pancreatic cystic neoplasms. Pancreatology. 2016 Sep-Oct; 16(5):888-92.
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Coutinho AE, Kipari TM, Zhang Z, Esteves CL, Lucas CD, Gilmour JS, Webster SP, Walker BR, Hughes J, Savill JS, Seckl JR, Rossi AG, Chapman KE. 11ß-Hydroxysteroid Dehydrogenase Type 1 Is Expressed in Neutrophils and Restrains an Inflammatory Response in Male Mice. Endocrinology. 2016 07; 157(7):2928-36.
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Singh VK, Hauer-Jensen M. ?-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. Int J Mol Sci. 2016 May 03; 17(5).
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Goh BK, Kam JH, Lee SY, Chan CY, Allen JC, Jeyaraj P, Cheow PC, Chow PK, Ooi LL, Chung AY. Significance of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and prognostic nutrition index as preoperative predictors of early mortality after liver resection for huge (=10?cm) hepatocellular carcinoma. J Surg Oncol. 2016 May; 113(6):621-7.
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Goh BK, Chok AY, Allen JC, Quek R, Teo MC, Chow PK, Chung AY, Ong HS, Wong WK. Blood neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios are independent prognostic factors for surgically resected gastrointestinal stromal tumors. Surgery. 2016 Apr; 159(4):1146-56.
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Maltez VI, Tubbs AL, Cook KD, Aachoui Y, Falcone EL, Holland SM, Whitmire JK, Miao EA. Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium. Immunity. 2015 Nov 17; 43(5):987-97.
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Stasulli NM, Eichelberger KR, Price PA, Pechous RD, Montgomery SA, Parker JS, Goldman WE. Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague. mBio. 2015 Oct 13; 6(5):e01530-15.
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Sonbol MB, Firwana B, Diab M, Zarzour A, Witzig TE. The Effect of a Neutropenic Diet on Infection and Mortality Rates in Cancer Patients: A Meta-Analysis. Nutr Cancer. 2015; 67(8):1230-8.
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Stolarz AJ, Farris RA, Wiley CA, O'Brien CE, Price ET. Fenofibrate Attenuates Neutrophilic Inflammation in Airway Epithelia: Potential Drug Repurposing for Cystic Fibrosis. Clin Transl Sci. 2015 Dec; 8(6):696-701.
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Franco AT, Corken A, Ware J. Platelets at the interface of thrombosis, inflammation, and cancer. Blood. 2015 Jul 30; 126(5):582-8.
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Elwood H, Berry RS, Gardner JM, Shalin SC. Superficial fibrin thrombi … and other findings: a review of the histopathology of human scabietic infections. J Cutan Pathol. 2015 May; 42(5):346-52.
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Falcão SA, Weinkopff T, Hurrell BP, Celes FS, Curvelo RP, Prates DB, Barral A, Borges VM, Tacchini-Cottier F, de Oliveira CI. Exposure to Leishmania braziliensis triggers neutrophil activation and apoptosis. PLoS Negl Trop Dis. 2015 Mar; 9(3):e0003601.
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Gao Y, Yang P, Shen H, Yu H, Song X, Zhang L, Zhang P, Cheng H, Xie Z, Hao S, Dong F, Ma S, Ji Q, Bartlow P, Ding Y, Wang L, Liu H, Li Y, Cheng H, Miao W, Yuan W, Yuan Y, Cheng T, Xie XQ. Small-molecule inhibitors targeting INK4 protein p18(INK4C) enhance ex vivo expansion of haematopoietic stem cells. Nat Commun. 2015 Feb 18; 6:6328.
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Liao HJ, Chyuan IT, Wu CS, Lin SW, Chen KH, Tsai HF, Hsu PN. Increased neutrophil infiltration, IL-1 production and a SAPHO syndrome-like phenotype in PSTPIP2-deficient mice. Rheumatology (Oxford). 2015 Jul; 54(7):1317-26.
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Svahn SL, Grahnemo L, Pálsdóttir V, Nookaew I, Wendt K, Gabrielsson B, Schéle E, Benrick A, Andersson N, Nilsson S, Johansson ME, Jansson JO. Dietary polyunsaturated fatty acids increase survival and decrease bacterial load during septic Staphylococcus aureus infection and improve neutrophil function in mice. Infect Immun. 2015 Feb; 83(2):514-21.
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Hakeem AR, Marangoni G, Chapman SJ, Young RS, Nair A, Hidalgo EL, Toogood GJ, Wyatt JI, Lodge PA, Prasad KR. Does the extent of lymphadenectomy, number of lymph nodes, positive lymph node ratio and neutrophil-lymphocyte ratio impact surgical outcome of perihilar cholangiocarcinoma? Eur J Gastroenterol Hepatol. 2014 Sep; 26(9):1047-54.
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Parajuli S, Achanta L, Hopkins RH, Post G. Neutrophilic leukemoid reaction in a patient with high grade sarcoma. J Ark Med Soc. 2014 Sep; 111(4):66-7.
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Long G, Waller EK, Gregurek S, Tricot G, Marschner S, Bill J. Evaluation of the spectra Optia® mononuclear cell collection procedure in multiple myeloma patients. J Clin Apher. 2015 Feb; 30(1):1-7.
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Wu L, Ong S, Talor MV, Barin JG, Baldeviano GC, Kass DA, Bedja D, Zhang H, Sheikh A, Margolick JB, Iwakura Y, Rose NR, Ciháková D. Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy. J Exp Med. 2014 Jun 30; 211(7):1449-64.
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Corken A, Russell S, Dent J, Post SR, Ware J. Platelet glycoprotein Ib-IX as a regulator of systemic inflammation. Arterioscler Thromb Vasc Biol. 2014 May; 34(5):996-1001.
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Pechous RD, Sivaraman V, Price PA, Stasulli NM, Goldman WE. Early host cell targets of Yersinia pestis during primary pneumonic plague. PLoS Pathog. 2013; 9(10):e1003679.
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O'Brien CE, Price ET. The blood neutrophil to lymphocyte ratio correlates with clinical status in children with cystic fibrosis: a retrospective study. PLoS One. 2013; 8(10):e77420.
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Demissie DE, Kaplan SL, Romero JR, Leake JA, Barson WJ, Halasa NB, Byington CL, Shetty AK, Tan TQ, Hoffman JA, Lin PL, Edwards KM, Mason EO, Cooperstock MS. Altered neutrophil counts at diagnosis of invasive meningococcal infection in children. Pediatr Infect Dis J. 2013 Oct; 32(10):1070-2.
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Khandpur R, Carmona-Rivera C, Vivekanandan-Giri A, Gizinski A, Yalavarthi S, Knight JS, Friday S, Li S, Patel RM, Subramanian V, Thompson P, Chen P, Fox DA, Pennathur S, Kaplan MJ. NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Sci Transl Med. 2013 Mar 27; 5(178):178ra40.
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Anzalone CL, Cohen PR. Acute febrile neutrophilic dermatosis (Sweet's syndrome). Curr Opin Hematol. 2013 Jan; 20(1):26-35.
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Jaeschke H, McGill MR, Williams CD. Pathophysiological relevance of neutrophils in acetaminophen hepatotoxicity. Hepatology. 2013 Jan; 57(1):419.
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Meriläinen S, Mäkelä J, Jensen HA, Dahlbacka S, Lehtonen S, Karhu T, Herzig KH, Kröger M, Koivukangas V, Koskenkari J, Ohtonen P, Karttunen T, Lehenkari P, Juvonen T. Portal vein cytokines in the early phase of acute experimental oedematous and necrotizing porcine pancreatitis. Scand J Gastroenterol. 2012 Nov; 47(11):1375-85.
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Price ET, Welder GJ, Zineh I. Modulatory effect of fenofibrate on endothelial production of neutrophil chemokines IL-8 and ENA-78. Cardiovasc Drugs Ther. 2012 Apr; 26(2):95-9.
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von Brühl ML, Stark K, Steinhart A, Chandraratne S, Konrad I, Lorenz M, Khandoga A, Tirniceriu A, Coletti R, Köllnberger M, Byrne RA, Laitinen I, Walch A, Brill A, Pfeiler S, Manukyan D, Braun S, Lange P, Riegger J, Ware J, Eckart A, Haidari S, Rudelius M, Schulz C, Echtler K, Brinkmann V, Schwaiger M, Preissner KT, Wagner DD, Mackman N, Engelmann B, Massberg S. Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. J Exp Med. 2012 Apr 09; 209(4):819-35.
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Ostanin DV, Kurmaeva E, Furr K, Bao R, Hoffman J, Berney S, Grisham MB. Acquisition of antigen-presenting functions by neutrophils isolated from mice with chronic colitis. J Immunol. 2012 Feb 01; 188(3):1491-502.
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Harrison MK, Hiatt KH, Smoller BR, Cheung WL. A case of cutaneous Scedosporium infection in an immunocompromised patient. J Cutan Pathol. 2012 Apr; 39(4):458-60.
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Elbahlawan LM, Morrison RR, Jeha S, Cheng C, Liu W, Fiser RT. Impact of neutrophil recovery on oxygenation in pediatric oncology patients with acute hypoxemic respiratory failure. J Pediatr Hematol Oncol. 2011 Oct; 33(7):e296-9.
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Romero CD, Varma TK, Hobbs JB, Reyes A, Driver B, Sherwood ER. The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection. Infect Immun. 2011 Sep; 79(9):3576-87.
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Rank RG, Whittimore J, Bowlin AK, Wyrick PB. In vivo ultrastructural analysis of the intimate relationship between polymorphonuclear leukocytes and the chlamydial developmental cycle. Infect Immun. 2011 Aug; 79(8):3291-301.
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Lacy HM, Bowlin AK, Hennings L, Scurlock AM, Nagarajan UM, Rank RG. Essential role for neutrophils in pathogenesis and adaptive immunity in Chlamydia caviae ocular infections. Infect Immun. 2011 May; 79(5):1889-97.
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